This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SIRT6 Antibody
catalog :
NB100-2522
quantity :
0.1 ml (also 0.025 ml)
price :
329 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 5
Reference
Zhang L, Bai L, Ren Q, Sun G, Si Y. Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70. Mol Immunol. 2018;101:312-318 pubmed publisher
Xia Y, Hua R, Juan C, Zhong Z, Tao C, Fang R, et al. SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression. Front Pharmacol. 2018;9:194 pubmed publisher
Wang L, Guo W, Ma J, Dai W, Liu L, Guo S, et al. Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling. Autophagy. 2018;14:518-533 pubmed publisher
Tao N, Ren J, Tang H, Ran L, Zhou H, Liu B, et al. Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma. Biochem Biophys Res Commun. 2017;485:713-719 pubmed publisher
Ran L, Chen Y, Zhang Z, Tao N, Ren J, Zhou L, et al. SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway. Clin Cancer Res. 2016;22:3372-82 pubmed publisher
product information
SKU :
NB100-2522
product name :
SIRT6 Antibody
unit size :
0.1 ml (also 0.025 ml)
Description :
The SIRT6 Antibody from Novus is a rabbit polyclonal antibody to SIRT6. This antibody reacts with human, mouse, rat. The SIRT6 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
target :
SIRT6
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to a C-terminal region of the mouse SIRT6 protein (within residues 250-334). [Swiss-Prot P59941]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat
theoretical molecular weight :
37 kDa
gene symbol :
SIRT6
catalog number base :
NB100-2522
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
2020 Proposedprice USD :
329 USD
alt names :
EC 3.5.1.-, NAD-dependent deacetylase sirtuin-6, SIR2L6sir2-related protein type 6, SIR2-like protein 6, sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6, sirtuin 6, sirtuin type 6
storage :
Store at 4C. Do not freeze.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.