DARC Antibody | Novus Biologicals NB100-2421 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DARC Antibody

catalog :

NB100-2421

quantity :

0.1 mg (also 0.025 mg)

price :

409 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 9

Reference
Raslan A, Pham T, Lee J, Hong J, Schmottlach J, Nicolas K, et al. Single Cell Transcriptomics of Fibrotic Lungs Unveils Aging-associated Alterations in Endothelial and Epithelial Cell Regeneration. bioRxiv. 2023;: pubmed publisher
He Y, Kim J, Tacconi C, Moody J, Dieterich L, Anzengruber F, et al. Mediators of Capillary-to-Venule Conversion in the Chronic Inflammatory Skin Disease Psoriasis. J Invest Dermatol. 2022;142:3313-3326.e13 pubmed publisher
He Y, Tacconi C, Dieterich L, Kim J, Restivo G, Gousopoulos E, et al. Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling. Cells. 2022;11: pubmed publisher
Hernández Aguilera A, Fibla M, Cabré N, Luciano Mateo F, Camps J, Fernández Arroyo S, et al. Chemokine (C-C motif) ligand 2 and coronary artery disease: Tissue expression of functional and atypical receptors. Cytokine. 2020;126:154923 pubmed publisher
Jenkins B, Martini R, Hire R, Brown A, Bennett B, Brown I, et al. Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry. Cancer Epidemiol Biomarkers Prev. 2019;28:690-700 pubmed publisher
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher
Davis M, Walens A, Hire R, Mumin K, Brown A, Ford D, et al. Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1)/Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele. PLoS ONE. 2015;10:e0140098 pubmed publisher
Yu K, Wang X, Yang C, Zeng X, Shao Z. Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse. Oncotarget. 2015;6:26519-27 pubmed publisher
Chuang C, Guh J, Lu C, Wang Y, Chen H, Chuang L. Steap4 attenuates high glucose and S100B-induced effects in mesangial cells. J Cell Mol Med. 2015;19:1234-44 pubmed publisher

product information

master code :

NB100-2421

SKU :

NB100-2421

product name :

DARC Antibody

unit size :

0.1 mg (also 0.025 mg)

description :

The DARC Antibody from Novus is a goat polyclonal antibody to DARC. This antibody reacts with human. The DARC Antibody has been validated for the following applications: IF/IHC,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Western Blot,Peptide ELISA.

target :

DARC

category :

Primary Antibodies

buffer :

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

clonality :

Polyclonal

concentration :

0.5 mg/ml

conjugate :

Unconjugated

host :

Goat

immunogen :

Peptide with sequence HRAELSPSTENSSQLDFED-C corresponding to N-Terminus according to NP_001116423.1, NP_002027.2.

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human

specificity :

This antibody is expected to recognize both reported isoforms (NP_001116423

theoretical molecular weight :

36 kDa

gene symbol :

ACKR1

accessionNumbers :

Q16570

applications :

IF/IHC,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Western Blot,Peptide ELISA

USD :

409 USD

alt names :

CCBP1, CD234, CD234 antigen, Dfy, Duffy antigen/chemokine receptor, Duffy blood group antigen, Duffy blood group, chemokine receptor, Fy glycoprotein, FYDuffy blood group, Glycoprotein D, GPDWBCQ1, GpFy, Plasmodium vivax receptor

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage