product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
OCT4 Antibody - BSA Free
catalog :
NB100-2379
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 50
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 4b
Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed publisher
Zhang R, Zhang X, Zhang W, Cui W, Xiao Y, Liu L, et al. Sohlh2 Regulates the Stemness and Differentiation of Colon Cancer Stem Cells by Downregulating LncRNA-H19 Transcription. Mol Cancer Res. 2023;21:115-126 pubmed publisher
Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Sci Adv. 2022;8:eabo5000 pubmed publisher
Panda D, Bai X, Zhang Y, Stylianesis N, Koromilas A, Lipman M, et al. SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis. J Clin Invest. 2022;132: pubmed publisher
Hekman K, Koss K, Ivancic D, He C, Wertheim J. Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase. Stem Cells Transl Med. 2022;11:1151-1164 pubmed publisher
Bååth M, Jönsson J, Westbom Fremer S, Martín de la Fuente L, Tran L, Malander S, et al. MET Expression and Cancer Stem Cell Networks Impact Outcome in High-Grade Serous Ovarian Cancer. Genes (Basel). 2021;12: pubmed publisher
Yang J, Liu H, Sun H, Wang Z, Zhang R, Liu Y, et al. Construction of induced pluripotent stem cell line (ZZUi0017-A) from the fibroblast cells of a female patient with CACNA1A mutation by unintegrated reprogramming approach. Stem Cell Res. 2020;48:101946 pubmed publisher
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed publisher
Szczurkowska J, Lee S, Guo A, Cwetsch A, Khan T, Rao S, et al. A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development. Cell Rep. 2020;31:107519 pubmed publisher
Ripamonti S, Shomroni O, Rhee J, Chowdhury K, Jahn O, Hellmann K, et al. SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. J Neurochem. 2020;: pubmed publisher
Yang T, Qin J, Zhang Q, Sun H, Wang Z, Yang J, et al. Generation of induced pluripotent stem cell line (ZZUi0018-A ) from a patient with spinocerebellar ataxia type 6. Stem Cell Res. 2020;44:101777 pubmed publisher
Maus L, Lee C, Altas B, Sertel S, Weyand K, Rizzoli S, et al. Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses. Cell Rep. 2020;30:3632-3643.e8 pubmed publisher
Gao Y, Wang Y, Wang Z, Sun H, Zhang R, Yang J, et al. Generation of induced pluripotent stem cell line (ZZUi0016-A) from dermal fibroblasts of a normal human. Stem Cell Res. 2020;43:101717 pubmed publisher
Kim B, Jeong Y, Wong M, Martin L. DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations. Acta Neuropathol Commun. 2020;8:7 pubmed publisher
Toh M, Brooks J, Strassmaier T, Haedo R, Puryear C, Roth B, et al. Application of High-Throughput Automated Patch-Clamp Electrophysiology to Study Voltage-Gated Ion Channel Function in Primary Cortical Cultures. SLAS Discov. 2020;25:447-457 pubmed publisher
Bonazzi S, Goold C, Gray A, Thomsen N, Nunez J, Karki R, et al. Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders. J Med Chem. 2020;63:1068-1083 pubmed publisher
Sen T, Saha P, Gupta R, Foley L, Jiang T, Abakumova O, et al. Aberrant ER Stress Induced Neuronal-IFNβ Elicits White Matter Injury Due to Microglial Activation and T-Cell Infiltration after TBI. J Neurosci. 2020;40:424-446 pubmed publisher
Hyvärinen T, Hyysalo A, Kapucu F, Aarnos L, Vinogradov A, Eglen S, et al. Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures. Sci Rep. 2019;9:17125 pubmed publisher
Subramanian J, Michel K, Benoit M, Nedivi E. CPG15/Neuritin Mimics Experience in Selecting Excitatory Synapses for Stabilization by Facilitating PSD95 Recruitment. Cell Rep. 2019;28:1584-1595.e5 pubmed publisher
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed publisher
Gasset Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019;102:339-357.e7 pubmed publisher
Kobayakawa K, DePetro K, Zhong H, Pham B, Hara M, Harada A, et al. Locomotor Training Increases Synaptic Structure With High NGL-2 Expression After Spinal Cord Hemisection. Neurorehabil Neural Repair. 2019;33:225-231 pubmed publisher
Sohni A, Tan K, Song H, Burow D, de Rooij D, Laurent L, et al. The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Rep. 2019;26:1501-1517.e4 pubmed publisher
Bathini P, Mottas A, Jaquet M, Brai E, Alberi L. Progressive signaling changes in the olfactory nerve of patients with Alzheimer's disease. Neurobiol Aging. 2019;76:80-95 pubmed publisher
Aiken J, Moore J, Bates E. TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity. Hum Mol Genet. 2019;28:1227-1243 pubmed publisher
Ambrozkiewicz M, Schwark M, Kishimoto Suga M, Borisova E, Hori K, Salazar Lázaro A, et al. Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140. Neuron. 2018;: pubmed publisher
López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher
Han Y, Bedarida T, Ding Y, Somba B, Lu Q, Wang Q, et al. β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4. Mol Cell. 2018;71:1064-1078.e5 pubmed publisher
Khan S, LaCroix M, Boyle G, Sherman M, Brown J, Amar F, et al. Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathol. 2018;136:589-605 pubmed publisher
Zhu L, Ni H, Chen R, Chang L, Shi H, Qiu D, et al. Hippocampal nuclear factor kappa B accounts for stress-induced anxiety behaviors via enhancing neuronal nitric oxide synthase (nNOS)-carboxy-terminal PDZ ligand of nNOS-Dexras1 coupling. J Neurochem. 2018;: pubmed publisher
Stankova T, Piepkorn L, Bayer T, Jahn O, Tirard M. SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. Aging Cell. 2018;17:e12760 pubmed publisher
Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed publisher
Paavilainen T, Pelkonen A, Mäkinen M, Peltola M, Huhtala H, Fayuk D, et al. Effect of prolonged differentiation on functional maturation of human pluripotent stem cell-derived neuronal cultures. Stem Cell Res. 2018;27:151-161 pubmed publisher
Cheng C, Chang J, Huang S, Lin H, Ho A, Lim K, et al. YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells. PLoS ONE. 2017;12:e0182149 pubmed publisher
Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher
Amar F, Sherman M, Rush T, LARSON M, Boyle G, Chang L, et al. The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Sci Signal. 2017;10: pubmed publisher
Zhao J, Davis M, Martens Y, Shinohara M, Graff Radford N, Younkin S, et al. APOE ?4/?4 diminishes neurotrophic function of human iPSC-derived astrocytes. Hum Mol Genet. 2017;26:2690-2700 pubmed publisher
McCulloh C, Olson J, Zhou Y, Wang Y, Besner G. Stem cells and necrotizing enterocolitis: A direct comparison of the efficacy of multiple types of stem cells. J Pediatr Surg. 2017;52:999-1005 pubmed publisher
Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed publisher
Lagerlöf O, Hart G, Huganir R. O-GlcNAc transferase regulates excitatory synapse maturity. Proc Natl Acad Sci U S A. 2017;114:1684-1689 pubmed publisher
Ciaraldi T, Ryan A, Mudaliar S, Henry R. Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes. PLoS ONE. 2016;11:e0158209 pubmed publisher
Verma N, Ly H, Liu M, Chen J, Zhu H, Chow M, et al. Intraneuronal Amylin Deposition, Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats. J Alzheimers Dis. 2016;53:259-72 pubmed publisher
Haas L, Salazar S, Kostylev M, Um J, Kaufman A, Strittmatter S. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain. 2016;139:526-46 pubmed publisher
Łupicka M, Socha B, Szczepańska A, Korzekwa A. Expression of pluripotency markers in the bovine uterus with adenomyosis. Reprod Biol Endocrinol. 2015;13:110 pubmed publisher
Lin H, Lee D, Wang H, Chi Y, Chiu I. Activation of FGF1B Promoter and FGF1 Are Involved in Cardiogenesis Through the Signaling of PKC, but Not MAPK. Stem Cells Dev. 2015;24:2853-63 pubmed publisher
Lu H, Samanta D, Xiang L, Zhang H, Hu H, Chen I, et al. Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. Proc Natl Acad Sci U S A. 2015;112:E4600-9 pubmed publisher
Zhou H, Liu G. Regulation of density of functional presynaptic terminals by local energy supply. Mol Brain. 2015;8:42 pubmed publisher
Darekar S, Mushtaq M, Gurrapu S, Kovalevska L, Drummond C, Petruchek M, et al. Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts. Oncotarget. 2015;6:21016-28 pubmed
Usui Y, Westenskow P, Kurihara T, Aguilar E, Sakimoto S, Paris L, et al. Neurovascular crosstalk between interneurons and capillaries is required for vision. J Clin Invest. 2015;125:2335-46 pubmed publisher
Schwerk A, Altschüler J, Roch M, Gossen M, Winter C, Berg J, et al. Human adipose-derived mesenchymal stromal cells increase endogenous neurogenesis in the rat subventricular zone acutely after 6-hydroxydopamine lesioning. Cytotherapy. 2015;17:199-214 pubmed publisher
product information
brand :
Novus
MasterCode :
NB100-2379
SKU :
NB100-2379
product name :
OCT4 Antibody - BSA Free
Description :
The OCT4 Antibody - BSA Free from NB100-2379 is a nb100-2379 antibody to . This antibody reacts with cellular markers, chromatin research, glia markers, neuroscience, oligodendrocyte cell markers, pancreatic stem cell markers, stem cell markers, stem cells, transcription factors and regulators. The OCT4 Antibody - BSA Free has been validated for the following applications: Q01860.
target :
4-Oct
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human OCT4 protein (between residues 100-200) [UniProt# Q01860]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat, Bovine, Primate
theoretical molecular weight :
40 kDa
gene symbol :
POU5F1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2379-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2379-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Immunohistochemistry-Paraffin-NB100-2379-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Immunohistochemistry-Paraffin-NB100-2379-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody---BSA-Free-Flow-Cytometry-NB100-2379-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody---BSA-Free-Flow-Cytometry-NB100-2379-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Western-Blot-NB100-2379-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/OCT4-Antibody-Flow-Cytometry-NB100-2379-img0021.jpg
accessionNumbers :
Q01860
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
class 5, transcription factor 1, MGC22487, Oct-3, OCT3Oct4, Oct-4, Octamer-binding protein 3, otc-4, OTF3POU domain class 5, transcription factor 1, OTF4, POU class 5 homeobox 1, POU-type homeodomain-containing DNA-binding protein
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.