KAP1 [p Ser824] Antibody | Novus Biologicals NB100-2350 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

KAP1 [p Ser824] Antibody

catalog :

NB100-2350

quantity :

0.1 ml

price :

499 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

4A794.15

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 104

Reference
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Chen Y, Sheu J, Sun C, Huang T, Lin Y, Yip H. MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis. Mol Med. 2020;26:46 pubmed publisher
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Kim J, Sun C, Tran A, Chin P, Ruiz P, Wang K, et al. The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening. Nat Struct Mol Biol. 2019;26:213-219 pubmed publisher
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Bernal A, Moltó Abad M, Dominguez D, Tusell L. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells. Oncotarget. 2018;9:27151-27170 pubmed publisher
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Panneer Selvam S, Roth B, Nganga R, Kim J, Cooley M, Helke K, et al. Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018;293:9784-9800 pubmed publisher
Jahn A, Rane G, Paszkowski Rogacz M, Sayols S, Bluhm A, Han C, et al. ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO Rep. 2017;18:929-946 pubmed publisher
Jeitany M, Bakhos Douaihy D, Silvestre D, Pineda J, Ugolin N, Moussa A, et al. Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance. Oncotarget. 2017;8:26269-26280 pubmed publisher
Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee C, et al. Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. J Leukoc Biol. 2017;101:927-947 pubmed publisher
Fouquerel E, Lormand J, Bose A, Lee H, Kim G, Li J, et al. Oxidative guanine base damage regulates human telomerase activity. Nat Struct Mol Biol. 2016;23:1092-1100 pubmed publisher
Bisht K, Smith E, Tesmer V, Nandakumar J. Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc Natl Acad Sci U S A. 2016;113:13021-13026 pubmed
Konishi A, Izumi T, Shimizu S. TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends. J Biol Chem. 2016;291:20798-810 pubmed publisher
Picco V, Coste I, Giraud Panis M, Renno T, Gilson E, Pages G. ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2. Oncotarget. 2016;7:46615-46627 pubmed publisher
Shukla S, Schmidt J, Goldfarb K, Cech T, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016;23:286-92 pubmed publisher
Kim Y, Kim K, Lee S, Hong S, Moon J, Yoon E, et al. Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma. Theranostics. 2016;6:357-68 pubmed publisher
Hasegawa D, Okabe S, Okamoto K, Nakano I, Shin ya K, Seimiya H. G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells. Biochem Biophys Res Commun. 2016;471:75-81 pubmed publisher
Altieri P, Barisione C, Lazzarini E, Garuti A, Bezante G, Canepa M, et al. Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes. J Am Heart Assoc. 2016;5: pubmed publisher
Xi L, Schmidt J, Zaug A, Ascarrunz D, Cech T. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015;16:231 pubmed publisher
Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
Kijas A, Lim Y, Bolderson E, Cerosaletti K, Gatei M, Jakob B, et al. ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Res. 2015;43:8352-67 pubmed publisher
Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher
Burla R, Carcuro M, Raffa G, Galati A, Raimondo D, Rizzo A, et al. AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance. PLoS Genet. 2015;11:e1005167 pubmed publisher
Panneer Selvam S, De Palma R, Oaks J, Oleinik N, Peterson Y, Stahelin R, et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015;8:ra58 pubmed publisher
Fujita T, Yuno M, Okuzaki D, Ohki R, Fujii H. Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing. PLoS ONE. 2015;10:e0123387 pubmed publisher
Schertzer M, Jouravleva K, Perderiset M, Dingli F, Loew D, Le Guen T, et al. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA. Nucleic Acids Res. 2015;43:1834-47 pubmed publisher
Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D Angelo C, et al. A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds. Nucleic Acids Res. 2015;43:1759-69 pubmed publisher
Freund A, Zhong F, Venteicher A, Meng Z, Veenstra T, Frydman J, et al. Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell. 2014;159:1389-403 pubmed publisher
Kocak H, Ballew B, Bisht K, Eggebeen R, Hicks B, Suman S, et al. Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1. Genes Dev. 2014;28:2090-102 pubmed publisher
Acharya S, Kaul Z, Gocha A, Martinez A, Harris J, Parvin J, et al. Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells. PLoS ONE. 2014;9:e103819 pubmed publisher
Bai Y, Lathia J, Zhang P, Flavahan W, Rich J, Mattson M. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. Glia. 2014;62:1687-98 pubmed publisher
Edwards D, Orren D, Machwe A. Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2. Nucleic Acids Res. 2014;42:7748-61 pubmed publisher
Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, et al. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model. PLoS ONE. 2014;9:e97599 pubmed publisher
Ohishi T, Muramatsu Y, Yoshida H, Seimiya H. TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation. Mol Cell Biol. 2014;34:2464-78 pubmed publisher
Stimpson K, Sullivan L, Kuo M, Sullivan B. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS ONE. 2014;9:e92432 pubmed publisher
Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau D, et al. Human RECQL1 participates in telomere maintenance. Nucleic Acids Res. 2014;42:5671-88 pubmed publisher
Münch S, Weidtkamp Peters S, Klement K, Grigaravicius P, Monajembashi S, Salomoni P, et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol. 2014;34:1733-46 pubmed publisher
Queisser A, Heeg S, Thaler M, von Werder A, Opitz O. Inhibition of telomerase induces alternative lengthening of telomeres during human esophageal carcinogenesis. Cancer Genet. 2013;206:374-86 pubmed publisher
Nakashima M, Nandakumar J, Sullivan K, Espinosa J, Cech T. Inhibition of telomerase recruitment and cancer cell death. J Biol Chem. 2013;288:33171-80 pubmed publisher
Saha B, Zitnik G, Johnson S, Nguyen Q, Risques R, Martin G, et al. DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations. Front Genet. 2013;4:129 pubmed publisher
Kamranvar S, Chen X, Masucci M. Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus. Oncogene. 2013;32:5522-30 pubmed publisher
Zhou J, Richardson M, Reddy V, Menon M, Barrack E, Reddy G, et al. Structural and functional association of androgen receptor with telomeres in prostate cancer cells. Aging (Albany NY). 2013;5:3-17 pubmed
Gocha A, Nuovo G, Iwenofu O, Groden J. Human sarcomas are mosaic for telomerase-dependent and telomerase-independent telomere maintenance mechanisms: implications for telomere-based therapies. Am J Pathol. 2013;182:41-8 pubmed publisher
Nandakumar J, Bell C, Weidenfeld I, Zaug A, Leinwand L, Cech T. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012;492:285-9 pubmed publisher
Orlotti N, Cimino Reale G, Borghini E, Pennati M, Sissi C, Perrone F, et al. Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage. Autophagy. 2012;8:1185-96 pubmed publisher
Suram A, Kaplunov J, Patel P, Ruan H, Cerutti A, Boccardi V, et al. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 2012;31:2839-51 pubmed publisher
Galati A, Magdinier F, Colasanti V, Bauwens S, Pinte S, Ricordy R, et al. TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner. PLoS ONE. 2012;7:e34386 pubmed publisher
Bhanot M, Smith S. TIN2 stability is regulated by the E3 ligase Siah2. Mol Cell Biol. 2012;32:376-84 pubmed publisher
Ghosh A, Rossi M, Singh D, Dunn C, Ramamoorthy M, Croteau D, et al. RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance. J Biol Chem. 2012;287:196-209 pubmed publisher
Abreu E, Terns R, Terns M. Visualization of human telomerase localization by fluorescence microscopy techniques. Methods Mol Biol. 2011;735:125-37 pubmed publisher
Kamranvar S, Masucci M. The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress. Leukemia. 2011;25:1017-25 pubmed publisher
Rodier F, Muñoz D, Teachenor R, Chu V, Le O, Bhaumik D, et al. DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. J Cell Sci. 2011;124:68-81 pubmed publisher
Stimpson K, Song I, Jauch A, Holtgreve Grez H, Hayden K, Bridger J, et al. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet. 2010;6: pubmed publisher
Benson E, Lee S, Aaronson S. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J Cell Sci. 2010;123:2605-12 pubmed publisher
Brugat T, Nguyen Khac F, Grelier A, Merle Béral H, Delic J. Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells. Blood. 2010;116:239-49 pubmed publisher
Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns R, et al. TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo. Mol Cell Biol. 2010;30:2971-82 pubmed publisher
Yoshitake K, Aoyagi H, Fujiwara H. Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1. Mob DNA. 2010;1:13 pubmed publisher
Tempera I, Deng Z, Atanasiu C, Chen C, D Erme M, Lieberman P. Regulation of Epstein-Barr virus OriP replication by poly(ADP-ribose) polymerase 1. J Virol. 2010;84:4988-97 pubmed publisher
Kim S, Richardson M, Chinnakannu K, Bai V, Menon M, Barrack E, et al. Androgen receptor interacts with telomeric proteins in prostate cancer cells. J Biol Chem. 2010;285:10472-6 pubmed publisher
Cesare A, Kaul Z, Cohen S, Napier C, Pickett H, Neumann A, et al. Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions. Nat Struct Mol Biol. 2009;16:1244-51 pubmed publisher
Brouwer A, Schimmel J, Wiegant J, Vertegaal A, Tanke H, Dirks R. Telomeric DNA mediates de novo PML body formation. Mol Biol Cell. 2009;20:4804-15 pubmed publisher
Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londono Vallejo A. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci U S A. 2009;106:15726-31 pubmed publisher
Caslini C, Connelly J, Serna A, Broccoli D, Hess J. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol. 2009;29:4519-26 pubmed publisher
Huda N, Tanaka H, Mendonca M, Gilley D. DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. Mol Cell Biol. 2009;29:3597-604 pubmed publisher
Bhattacharyya S, Keirsey J, Russell B, Kavecansky J, Lillard Wetherell K, Tahmaseb K, et al. Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates. J Biol Chem. 2009;284:14966-77 pubmed publisher
Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa Saito M, Kiyono T, et al. Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres. Genes Cells. 2008;13:1045-59 pubmed publisher
Huang F, Chang C, Lou P, Kuo I, Chien C, Chen C, et al. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells. Mol Cancer Res. 2008;6:955-64 pubmed publisher
Kim S, Davalos A, Heo S, Rodier F, Zou Y, Beausejour C, et al. Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes. J Cell Biol. 2008;181:447-60 pubmed publisher
Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H. Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation. Exp Cell Res. 2008;314:1115-24 pubmed publisher
Zhang Y, Zhang Z, Miao Z, Ding J. The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine. Mol Pharmacol. 2008;73:824-32 pubmed
Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns R, Terns M, et al. Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell. 2007;27:882-9 pubmed
Jiang W, Zhong Z, Henson J, Reddel R. Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. Oncogene. 2007;26:4635-47 pubmed
Barcaroli D, Dinsdale D, Neale M, Bongiorno Borbone L, Ranalli M, Munarriz E, et al. FLASH is an essential component of Cajal bodies. Proc Natl Acad Sci U S A. 2006;103:14802-7 pubmed
Barcaroli D, Bongiorno Borbone L, Terrinoni A, Hofmann T, Rossi M, Knight R, et al. FLASH is required for histone transcription and S-phase progression. Proc Natl Acad Sci U S A. 2006;103:14808-12 pubmed
Raz V, Carlotti F, Vermolen B, van der Poel E, Sloos W, Knaän Shanzer S, et al. Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. J Cell Sci. 2006;119:4247-56 pubmed
Bellon M, Datta A, Brown M, Pouliquen J, Couppie P, Kazanji M, et al. Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia. Int J Cancer. 2006;119:2090-7 pubmed
Biroccio A, Rizzo A, Elli R, Koering C, Belleville A, Benassi B, et al. TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells. Eur J Cancer. 2006;42:1881-8 pubmed
Luciani J, Depetris D, Usson Y, Metzler Guillemain C, Mignon Ravix C, Mitchell M, et al. PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase. J Cell Sci. 2006;119:2518-31 pubmed
Freibaum B, Counter C. hSnm1B is a novel telomere-associated protein. J Biol Chem. 2006;281:15033-6 pubmed
Tahara H, Shin Ya K, Seimiya H, Yamada H, Tsuruo T, Ide T. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells. Oncogene. 2006;25:1955-66 pubmed
Tanaka H, Mendonca M, Bradshaw P, Hoelz D, Malkas L, Meyn M, et al. DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. Proc Natl Acad Sci U S A. 2005;102:15539-44 pubmed
Johnson J, Varkonyi R, Schwalm J, Cragle R, Klein Szanto A, Patchefsky A, et al. Multiple mechanisms of telomere maintenance exist in liposarcomas. Clin Cancer Res. 2005;11:5347-55 pubmed
Hartmann N, Scherthan H. Characterization of the telomere complex, TERF1 and TERF2 genes in muntjac species with fusion karyotypes. Exp Cell Res. 2005;306:64-74 pubmed
Kaminker P, Plachot C, Kim S, Chung P, Crippen D, Petersen O, et al. Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2. J Cell Sci. 2005;118:1321-30 pubmed
Nijjar T, Bassett E, Garbe J, Takenaka Y, Stampfer M, Gilley D, et al. Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells. Oncogene. 2005;24:3369-76 pubmed
Bradshaw P, Stavropoulos D, Meyn M. Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. Nat Genet. 2005;37:193-7 pubmed
Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T. Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics. Cancer Cell. 2005;7:25-37 pubmed
Ahn B, Harrigan J, Indig F, Wilson D, Bohr V. Regulation of WRN helicase activity in human base excision repair. J Biol Chem. 2004;279:53465-74 pubmed
Houghtaling B, Cuttonaro L, Chang W, Smith S. A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr Biol. 2004;14:1621-31 pubmed
Kim S, Beausejour C, Davalos A, Kaminker P, Heo S, Campisi J. TIN2 mediates functions of TRF2 at human telomeres. J Biol Chem. 2004;279:43799-804 pubmed
Fotiadou P, Henegariu O, Sweasy J. DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line. Cancer Res. 2004;64:3830-7 pubmed
Seimiya H, Muramatsu Y, Smith S, Tsuruo T. Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation. Mol Cell Biol. 2004;24:1944-55 pubmed
Deng Z, Atanasiu C, Burg J, Broccoli D, Lieberman P. Telomere repeat binding factors TRF1, TRF2, and hRAP1 modulate replication of Epstein-Barr virus OriP. J Virol. 2003;77:11992-2001 pubmed
Stavropoulos D, Bradshaw P, Li X, Pasic I, Truong K, Ikura M, et al. The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis. Hum Mol Genet. 2002;11:3135-44 pubmed
Opresko P, Von Kobbe C, Laine J, Harrigan J, Hickson I, Bohr V. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J Biol Chem. 2002;277:41110-9 pubmed
Deng Z, Lezina L, Chen C, Shtivelband S, So W, Lieberman P. Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication. Mol Cell. 2002;9:493-503 pubmed
Cook B, Dynek J, Chang W, Shostak G, Smith S. Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol. 2002;22:332-42 pubmed
Johnson F, Marciniak R, McVey M, Stewart S, Hahn W, Guarente L. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J. 2001;20:905-13 pubmed
Scherthan H, Jerratsch M, Li B, Smith S, Hulten M, Lock T, et al. Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Mol Biol Cell. 2000;11:4189-203 pubmed
Okabe J, Eguchi A, Masago A, Hayakawa T, Nakanishi M. TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells. Hum Mol Genet. 2000;9:2639-50 pubmed

product information

brand :

Novus

MasterCode :

NB100-2350

SKU :

NB100-2350

product name :

KAP1 [p Ser824] Antibody

Description :

The KAP1 [p Ser824] Antibody from NB100-2350 is a nb100-2350 antibody to . This antibody reacts with phospho specific. The KAP1 [p Ser824] Antibody has been validated for the following applications: Q13263.

target :

KAP1

category :

Primary Antibodies

unit size :

0.1 ml

buffer :

TBS, 0.1% BSA

clonality :

Polyclonal

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

This KAP1 [p Ser824] Antibody was developed against mmunogen a synthetic phosphorylated peptide, which represents a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human, Mouse, Rat

gene symbol :

TRIM28

images :

https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Western-Blot-NB100-2350-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2350-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Immunohistochemistry-Paraffin-NB100-2350-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Western-Blot-NB100-2350-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Western-Blot-NB100-2350-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Immunohistochemistry-Paraffin-NB100-2350-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/KAP1-[p-Ser824]-Antibody-Immunoprecipitation-NB100-2350-img0016.jpg

accessionNumbers :

Q13263

applications :

Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Chromatin Immunoprecipitation (ChIP)

USD :

499 USD

alt names :

E3 SUMO-protein ligase TRIM28, EC 6.3.2.-, FLJ29029, KAP-1, KAP1KRAB-associated protein 1, KRIP-1, Nuclear corepressor KAP-1, RNF96KRAB-interacting protein 1, TF1B, TIF1-beta, TIF1BRING finger protein 96, transcription intermediary factor 1-beta, transcriptional intermediary factor 1-beta, tripartite motif containing 28, tripartite motif-containing 28, Tripartite motif-containing protein 28

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage