Rabbit Polyclonal LC3A Antibody [Biotin] | Novus Biologicals NB100-2331B product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Rabbit Polyclonal LC3A Antibody [Biotin]

catalog :

NB100-2331B

quantity :

0.1 ml

price :

379 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human, mouse, rat, dog, zebrafish

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rat western blot; human western blot; dog	Nakagawa S, Nishihara K, Inui K, Masuda S. Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury. Eur J Pharmacol. 2012;696:143-54 pubmed publisher

product information

Catalog Number :

NB100-2331B

Product Name :

Rabbit Polyclonal LC3A Antibody [Biotin]

List Price :

379 USD

product type :

Primary Antibodies

Package Size :

0.1 ml

AltNames :

ATG8E, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3A, lc3-i, ii, MAP1A/1B light chain 3 A, MAP1ALC3MAP1A/MAP1B LC3 A, MAP1BLC3MAP1A/MAP1B light chain 3 A, microtubule-associated protein 1 light chain 3 alphaMAP1 light chain 3-like protein 1, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3A

Buffer :

PBS

Clonality :

Polyclonal

Conjugate :

Biotin

Application Summary :

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Host :

Rabbit

Immunogen :

A synthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121). [UniProt# Q9GZQ8].

Localization :

LC3-I is cytoplasmic. LC3-II binds to the autophagic membranes.

Marker :

Autophagosome Marker

Preservative :

0.05% Sodium Azide

Purity :

Immunogen affinity purified

CrossReactivity :

Canine, Fish, Human, Mouse, Rat, Zebrafish

Specificity :

This antibody detects both LC3A and LC3B.

Storage :

Store at 4C in the dark.

Swissprot Human :

Q9GZQ8

Uses :

This LC3 antibody is useful for Western blot, Immunocytochemistry/Immunofluorescence (PMID 21545732), Immunoprecipitation and Immunohistochemistry paraffin embedded sections. By Western blot bands are seen at ~19 kDa, representing LC3-I, and ~17 kDa, representing LC3-II. In ICC/IF, cytoplasmic staining was observed in HeLa cells.Use in FLOW cytometry reported in scientific literature ( PMID 24419333)

Research Area :

Autophagy, Cancer, Cellular Markers, Cytoskeleton Markers, Hypoxia, Signal Transduction