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product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal LC3A Antibody [Alexa Fluor® 647]
catalog :
NB100-2331AF647
quantity :
0.1 ml
price :
379 USD
clonality :
polyclonal
host :
rabbit
conjugate :
AF647
reactivity :
human, mouse, rat, dog, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog Number :
NB100-2331AF647
Product Name :
Rabbit Polyclonal LC3A Antibody [Alexa Fluor® 647]
List Price :
379 USD
product type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
ATG8E, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3A, lc3-i, ii, MAP1A/1B light chain 3 A, MAP1ALC3MAP1A/MAP1B LC3 A, MAP1BLC3MAP1A/MAP1B light chain 3 A, microtubule-associated protein 1 light chain 3 alphaMAP1 light chain 3-like protein 1, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3A
Buffer :
50mM Sodium Borate
Clonality :
Polyclonal
Conjugate :
Alexa Fluor 647
Application Summary :
Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121). [UniProt# Q9GZQ8].
Localization :
LC3-I is cytoplasmic. LC3-II binds to the autophagic membranes.
Marker :
Autophagosome Marker
Notes :
Alexa Flour (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
Preservative :
0.05% Sodium Azide
Purity :
Immunogen affinity purified
CrossReactivity :
Canine, Fish, Human, Mouse, Rat, Zebrafish
Specificity :
This antibody detects both LC3A and LC3B.
Storage :
Store at 4C in the dark.
Swissprot Human :
Q9GZQ8
Uses :
This LC3 antibody is useful for Western blot, Immunocytochemistry/Immunofluorescence (PMID 21545732), Immunoprecipitation and Immunohistochemistry paraffin embedded sections. By Western blot bands are seen at ~19 kDa, representing LC3-I, and ~17 kDa, representing LC3-II. In ICC/IF, cytoplasmic staining was observed in HeLa cells.Use in FLOW cytometry reported in scientific literature ( PMID 24419333)
Research Area :
Autophagy, Cancer, Cellular Markers, Cytoskeleton Markers, Hypoxia, Neuroscience, Phospho Specific, Signal Transduction
company information

Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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