product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
HMGB1/HMG-1 Antibody
catalog :
NB100-2322
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 113
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 9a
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Baker B, Heazell A, Sibley C, Wright R, Bischof H, Beards F, et al. Hypoxia and oxidative stress induce sterile placental inflammation in vitro. Sci Rep. 2021;11:7281 pubmed publisher
Ghaffari S, Jang E, Naderinabi F, Sanwal R, Khosraviani N, Wang C, et al. Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2-SR-BI Axis. Arterioscler Thromb Vasc Biol. 2021;41:200-216 pubmed publisher
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Ghosh P, Guo Y, Ashrafi A, Chen J, Dey S, Zhong S, et al. Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation. Cancer Res. 2020;80:3542-3555 pubmed publisher
Becker L, O Connell J, Vo A, Cain M, Tampe D, Bizarro L, et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep. 2020;31:107701 pubmed publisher
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Chen S, Xing C, Huang D, Zhou C, Ding B, Guo Z, et al. Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions. Sci Adv. 2020;6:eaay6825 pubmed publisher
Kim M, Joo J, Lee S, Cho Y, Park C, Cho N. Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes. Cancers (Basel). 2020;12: pubmed publisher
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Evran S, Çalış F, Akkaya E, Baran O, Cevik S, Katar S, et al. The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model. Brain Res Bull. 2020;154:68-80 pubmed publisher
Recondo G, Mezquita L, Facchinetti F, Planchard D, Gazzah A, Bigot L, et al. Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer. Clin Cancer Res. 2020;26:242-255 pubmed publisher
Steenbrugge J, Vander Elst N, Demeyere K, De Wever O, Sanders N, van den Broeck W, et al. Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer. Front Immunol. 2019;10:2928 pubmed publisher
Xiao Y, Zhao H, Tian L, Nolley R, Diep A, Ernst A, et al. S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma. Cancer Res. 2019;79:5758-5768 pubmed publisher
Kennedy J, Wang X, Plouffe K, Dhanasekaran S, Hafez K, Palapattu G, et al. Clinical and morphologic review of 60 hereditary renal tumors from 30 hereditary renal cell carcinoma syndrome patients: lessons from a contemporary single institution series. Med Oncol. 2019;36:74 pubmed publisher
Matolay O, Beke L, Gyurkovics A, Francz M, Varjasi G, Rejto L, et al. Quantitative Analysis of Carbonic Anhydrase IX Uncovers Hypoxia-Related Functional Differences in Classical Hodgkin Lymphoma Subtypes. Int J Mol Sci. 2019;20: pubmed publisher
Domingo Vidal M, Whitaker Menezes D, Martos Rus C, Tassone P, Snyder C, Tuluc M, et al. Cigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell Carcinoma. Mol Cancer Res. 2019;17:1893-1909 pubmed publisher
Kitson S, Maskell Z, Sivalingam V, Shaw J, Crosbie E. Optimization of Window Study Endpoints in Endometrial Cancer. Front Oncol. 2019;9:428 pubmed publisher
Ron A, Dean Ben X, Gottschalk S, Razansky D. Volumetric optoacoustic imaging unveils high-resolution patterns of acute and cyclic hypoxia in a murine model of breast cancer. Cancer Res. 2019;: pubmed publisher
Reijnen C, van Weelden W, Arts M, Peters J, Rijken P, Van De Vijver K, et al. Poor outcome in hypoxic endometrial carcinoma is related to vascular density. Br J Cancer. 2019;120:1037-1044 pubmed publisher
Azam S, Porrello A, Harrison E, Leslie P, Liu X, Waugh T, et al. Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis. Oncogene. 2019;: pubmed publisher
Frost J, Ciulli A, Rocha S. RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response. Wellcome Open Res. 2019;4:17 pubmed publisher
Najjar Y, Menk A, Sander C, Rao U, Karunamurthy A, Bhatia R, et al. Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma. JCI Insight. 2019;4: pubmed publisher
Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed publisher
Mehes G, Matolay O, Beke L, Czenke M, Jona A, Miltenyi Z, et al. Hypoxia-related carbonic anhydrase IX expression is associated with unfavourable response to first-line therapy in classical Hodgkin's lymphoma. Histopathology. 2019;74:699-708 pubmed publisher
Neal J, Li X, Zhu J, Giangarrà V, Grzeskowiak C, Ju J, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175:1972-1988.e16 pubmed publisher
Kubo H, Hanaoka K, Kuriki Y, Komatsu T, Ueno T, Kojima R, et al. Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe. Sci Rep. 2018;8:17781 pubmed publisher
Young J, Coy H, Kim H, Douek M, Sisk A, Pantuck A, et al. Association of the Gross Appearance of Intratumoral Vascularity at MDCT With the Carbonic Anhydrase IX Score in Clear Cell Renal Cell Carcinoma. AJR Am J Roentgenol. 2018;211:1254-1258 pubmed publisher
Davis R, Kiss B, Trivedi D, Metzner T, Liao J, Gambhir S. Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype. ACS Nano. 2018;12:9669-9679 pubmed publisher
Greenhough A, Bagley C, Heesom K, Gurevich D, Gay D, Bond M, et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med. 2018;10: pubmed publisher
Burman A, Kropski J, Calvi C, Serezani A, Pascoalino B, Han W, et al. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight. 2018;3: pubmed publisher
Steenbrugge J, Breyne K, Demeyere K, De Wever O, Sanders N, van den Broeck W, et al. Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer. J Exp Clin Cancer Res. 2018;37:191 pubmed publisher
Balasundaram G, Ding L, Li X, Attia A, Dean Ben X, Ho C, et al. Noninvasive Anatomical and Functional Imaging of Orthotopic Glioblastoma Development and Therapy using Multispectral Optoacoustic Tomography. Transl Oncol. 2018;11:1251-1258 pubmed publisher
Li T, Liu B, Guan H, Mao W, Wang L, Zhang C, et al. PGE2 increases inflammatory damage in Escherichia coli-infected bovine endometrial tissue in vitro via the EP4-PKA signaling pathway. Biol Reprod. 2019;100:175-186 pubmed publisher
Lambrechts D, Wauters E, Boeckx B, Aibar S, Nittner D, Burton O, et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat Med. 2018;24:1277-1289 pubmed publisher
Ames S, Pastorekova S, Becker H. The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells. Oncotarget. 2018;9:27940-27957 pubmed publisher
Toonen L, Overzier M, Evers M, Leon L, van der Zeeuw S, Mei H, et al. Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model. Mol Neurodegener. 2018;13:31 pubmed publisher
Gao R, Ma J, Wen Z, Yang P, Zhao J, Xue M, et al. Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils. Oncoimmunology. 2018;7:e1438108 pubmed publisher
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, et al. Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance. Cell Metab. 2018;28:104-117.e5 pubmed publisher
Rosenberg T, Aaberg Jessen C, Petterson S, Kristensen B. Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia. CNS Oncol. 2018;7:CNS15 pubmed publisher
Kim S, Son M, Lee S, Park I, Kwak M, Han M, et al. High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation. Front Immunol. 2018;9:705 pubmed publisher
Dao M, Pécriaux A, Bessede T, Durrbach A, Mussini C, Guettier C, et al. BK virus-associated collecting duct carcinoma of the renal allograft in a kidney-pancreas allograft recipient. Oncotarget. 2018;9:15157-15163 pubmed publisher
Ferecatu I, Canal F, Fabbri L, Mazure N, Bouton C, Golinelli Cohen M. Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1? activation. PLoS ONE. 2018;13:e0194782 pubmed publisher
Corbet C, Bastien E, Draoui N, Doix B, Mignion L, Jordan B, et al. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects. Nat Commun. 2018;9:1208 pubmed publisher
Young J, Coy H, Kim H, Douek M, Sisk A, Belldegrun A, et al. Utility of multiphasic multidetector computed tomography in discriminating between clear cell renal cell carcinomas with high and low carbonic anhydrase-IX expression. Abdom Radiol (NY). 2018;43:2734-2742 pubmed publisher
Dreyer Andersen N, Almeida A, Jensen P, Kamand M, Okarmus J, Rosenberg T, et al. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells. PLoS ONE. 2018;13:e0191207 pubmed publisher
Boyd N, Walker K, Fried J, Hackney J, McDonald P, Benavides G, et al. Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. JCI Insight. 2017;2: pubmed publisher
Pinato D, Black J, Trousil S, Dina R, Trivedi P, Mauri F, et al. Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior. Oncoimmunology. 2017;6:e1358332 pubmed publisher
He L, Zhao C, Li Y, Du G, Liu K, Cui D, et al. Antiangiogenic effects of recombinant human endostatin in lung cancers. Mol Med Rep. 2018;17:79-86 pubmed publisher
Ou D, Garberis I, Adam J, Blanchard P, Nguyen F, Levy A, et al. Prognostic value of tissue necrosis, hypoxia-related markers and correlation with HPV status in head and neck cancer patients treated with bio- or chemo-radiotherapy. Radiother Oncol. 2018;126:116-124 pubmed publisher
Nakamura M, Zhang Y, Yang Y, Sonmez C, Zheng W, Huang G, et al. Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production. Proc Natl Acad Sci U S A. 2017;114:E9635-E9644 pubmed publisher
Wang D, Berglund A, Kenchappa R, Macaulay R, MULE J, Etame A. BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats. Sci Rep. 2017;7:9350 pubmed publisher
Bucau M, Laurent Bellue A, Poté N, Hentic O, Cros J, Mikail N, et al. 18F-FDG Uptake in Well-Differentiated Neuroendocrine Tumors Correlates with Both Ki-67 and VHL Pathway Inactivation. Neuroendocrinology. 2018;106:274-282 pubmed publisher
Klameth L, Rath B, Hochmaier M, Moser D, Redl M, Mungenast F, et al. Small cell lung cancer: model of circulating tumor cell tumorospheres in chemoresistance. Sci Rep. 2017;7:5337 pubmed publisher
Zhang Y, Sun M, Huang G, Yin L, Lai Q, Yang Y, et al. Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy. Proc Natl Acad Sci U S A. 2017;114:E5226-E5235 pubmed publisher
Takenaka M, Suzuki N, Mori M, Hirayama T, Nagasawa H, Morishige K. Iron regulatory protein 2 in ovarian endometrial cysts. Biochem Biophys Res Commun. 2017;487:789-794 pubmed publisher
Bousquet G, El Bouchtaoui M, Sophie T, Leboeuf C, De Bazelaire C, Ratajczak P, et al. Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer. Oncotarget. 2017;8:35205-35221 pubmed publisher
Tudisco L, Orlandi A, Tarallo V, De Falco S. Hypoxia activates placental growth factor expression in lymphatic endothelial cells. Oncotarget. 2017;8:32873-32883 pubmed publisher
Lee D, Cheul Oh S, Giles A, Jung J, Gilbert M, Park D. Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1? in human glioma stem cells. Oncotarget. 2017;8:40233-40245 pubmed publisher
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed publisher
Fraga A, Ribeiro R, Coelho A, Vizcaíno J, Coutinho H, Lopes J, et al. Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer. BMC Urol. 2017;17:12 pubmed publisher
Coleman L, Zou J, Crews F. Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7. J Neuroinflammation. 2017;14:22 pubmed publisher
Bulusu V, Tumanov S, Michalopoulou E, van den Broek N, Mackay G, Nixon C, et al. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation. Cell Rep. 2017;18:647-658 pubmed publisher
Tsuji T, Kurokawa Y, Chiche J, Pouysségur J, Sato H, Fukuzawa H, et al. Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters. J Biol Chem. 2017;292:2159-2173 pubmed publisher
Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
Frost J, Galdeano C, Soares P, Gadd M, Grzes K, Ellis L, et al. Potent and selective chemical probe of hypoxic signalling downstream of HIF-? hydroxylation via VHL inhibition. Nat Commun. 2016;7:13312 pubmed publisher
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Eikrem O, Strauss P, Beisland C, Scherer A, Landolt L, Flatberg A, et al. Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scand J Urol. 2016;50:452-462 pubmed
Huang Y, Lichtenberger L, Taylor M, Bottsford Miller J, Haemmerle M, Wagner M, et al. Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. Mol Cancer Ther. 2016;15:2894-2904 pubmed
Zhou M, Wen Z, Cheng F, Ma J, Li W, Ren H, et al. Tumor-released autophagosomes induce IL-10-producing B cells with suppressive activity on T lymphocytes via TLR2-MyD88-NF-κB signal pathway. Oncoimmunology. 2016;5:e1180485 pubmed publisher
Kim E, Kim G, Kim J, Park I, Shin J, Chai Y, et al. A Pyloric Gland-Phenotype Ovarian Mucinous Tumor Resembling Lobular Endocervical Glandular Hyperplasia in a Patient with Peutz-Jeghers Syndrome. J Pathol Transl Med. 2017;51:159-164 pubmed publisher
van Kuijk S, Gieling R, Niemans R, Lieuwes N, Biemans R, Telfer B, et al. The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLoS ONE. 2016;11:e0161040 pubmed publisher
Hirakawa T, Yashiro M, Doi Y, Kinoshita H, Morisaki T, Fukuoka T, et al. Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia. PLoS ONE. 2016;11:e0159912 pubmed publisher
Kim J, Lee S, Oh J, Park S, Park S, Hong S, et al. Development of Advanced Atherosclerotic Plaque by Injection of Inflammatory Proteins in a Rabbit Iliac Artery Model. Yonsei Med J. 2016;57:1095-105 pubmed publisher
Yoon C, Chang K, Lee J, Tap W, Hart C, Simon M, et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1? inhibition, and hypoxia-activated chemotherapy. Oncotarget. 2016;7:42844-42858 pubmed publisher
Leek R, Grimes D, Harris A, McIntyre A. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia. Adv Exp Med Biol. 2016;899:167-96 pubmed publisher
He H, Yang Y, Xiang Z, Yu L, Chouitar J, Yu J, et al. A Sensitive IHC Method for Monitoring Autophagy-Specific Markers in Human Tumor Xenografts. J Biomark. 2016;2016:1274603 pubmed publisher
Hecht J, Zsengellér Z, Spiel M, Karumanchi S, Rosen S. Revisiting decidual vasculopathy. Placenta. 2016;42:37-43 pubmed publisher
Xu W, Ghosh S, Comhair S, Asosingh K, Janocha A, Mavrakis D, et al. Increased mitochondrial arginine metabolism supports bioenergetics in asthma. J Clin Invest. 2016;126:2465-81 pubmed publisher
Badar T, Handisides D, Benito J, Richie M, Borthakur G, Jabbour E, et al. Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia. Am J Hematol. 2016;91:800-5 pubmed publisher
Faes S, Planche A, Uldry E, Santoro T, Pythoud C, Stehle J, et al. Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors. Oncotarget. 2016;7:36666-36680 pubmed publisher
Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, et al. Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines. PLoS ONE. 2016;11:e0154759 pubmed publisher
Eikrem O, Beisland C, Hjelle K, Flatberg A, Scherer A, Landolt L, et al. Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development. PLoS ONE. 2016;11:e0149743 pubmed publisher
Radoul M, Chaumeil M, Eriksson P, Wang A, Phillips J, Ronen S. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol Cancer Ther. 2016;15:1113-22 pubmed publisher
Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed publisher
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
Mitsuhashi A, Goto H, Saijo A, Trung V, Aono Y, Ogino H, et al. Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab. Nat Commun. 2015;6:8792 pubmed publisher
Feng Y, Yang S, Ma Y, Bai X, Chen X. Role of Toll-like receptors in diabetic renal lesions in a miniature pig model. Sci Adv. 2015;1:e1400183 pubmed publisher
André H, Tunik S, Aronsson M, Kvanta A. Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model. Invest Ophthalmol Vis Sci. 2015;56:6591-604 pubmed publisher
Klier M, Jamali S, Ames S, Schneider H, Becker H, Deitmer J. Catalytic activity of human carbonic anhydrase isoform IX is displayed both extra- and intracellularly. FEBS J. 2016;283:191-200 pubmed publisher
Islam S, Mokhtari R, Akbari P, Hatina J, Yeger H, Farhat W. Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN). Target Oncol. 2016;11:209-27 pubmed publisher
Kinoshita H, Yashiro M, Fukuoka T, Hasegawa T, Morisaki T, Kasashima H, et al. Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments. Carcinogenesis. 2015;36:1511-20 pubmed publisher
Jamali S, Klier M, Ames S, Barros L, McKenna R, Deitmer J, et al. Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function. Sci Rep. 2015;5:13605 pubmed publisher
Baine M, Turcu G, Zito C, Adeniran A, Camp R, Chen L, et al. Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens. Oncotarget. 2015;6:24990-5002 pubmed publisher
Song C, Lee Y, Griffin R, Park I, Koonce N, Hui S, et al. Indirect Tumor Cell Death After High-Dose Hypofractionated Irradiation: Implications for Stereotactic Body Radiation Therapy and Stereotactic Radiation Surgery. Int J Radiat Oncol Biol Phys. 2015;93:166-72 pubmed publisher
Ward C, Meehan J, Mullen P, Supuran C, Dixon J, Thomas J, et al. Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. Oncotarget. 2015;6:24856-70 pubmed publisher
Kasashima H, Yashiro M, Kinoshita H, Fukuoka T, Morisaki T, Masuda G, et al. Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia. Gastric Cancer. 2016;19:431-442 pubmed publisher
Yoon C, Lee H, Park D, Lee Y, Tap W, Eisinger Mathason T, et al. Hypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas. Br J Cancer. 2015;113:46-56 pubmed publisher
Brossa A, Grange C, Mancuso L, Annaratone L, Satolli M, Mazzone M, et al. Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation. Oncotarget. 2015;6:11295-309 pubmed
Dulloo I, Phang B, Othman R, Tan S, Vijayaraghavan A, Goh L, et al. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nat Cell Biol. 2015;17:511-23 pubmed publisher
Cotroneo E, Ashek A, Wang L, Wharton J, Dubois O, Bozorgi S, et al. Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. Circ Res. 2015;116:1680-90 pubmed publisher
Kang H, Kim I, Sung C, Shim J, Yu E. Expression of carbonic anhydrase 9 is a novel prognostic marker in resectable hepatocellular carcinoma. Virchows Arch. 2015;466:403-13 pubmed publisher
Lee H, Yoon C, Park D, Kim Y, Schmidt B, Lee Y, et al. Inhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature. Int J Radiat Oncol Biol Phys. 2015;91:621-30 pubmed publisher
Janmohamed S, Brinkhuizen T, Den Hollander J, Madern G, de Laat P, van Steensel M, et al. Support for the hypoxia theory in the pathogenesis of infantile haemangioma. Clin Exp Dermatol. 2015;40:431-7 pubmed publisher
Lin X, Zhang H, Tang N, Zhang X, Zhang W, Wang E, et al. Expression and diagnostic implications of carbonic anhydrase IX in several tumours with predominantly clear cell morphology. Histopathology. 2015;66:685-94 pubmed publisher
Dos Santos C, Tijeras Raballand A, Serova M, Sebbagh S, Slimane K, Faivre S, et al. Effects of preset sequential administrations of sunitinib and everolimus on tumour differentiation in Caki-1 renal cell carcinoma. Br J Cancer. 2015;112:86-94 pubmed publisher
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Kwon O, Park J, Ko G, Seo J, Jeong B, Kang K, et al. HIF-1α and CA-IX as predictors of locoregional control for determining the optimal treatment modality for early-stage laryngeal carcinoma. Head Neck. 2015;37:505-10 pubmed publisher
product information
brand :
Novus
MasterCode :
NB100-2322
SKU :
NB100-2322
product name :
HMGB1/HMG-1 Antibody
Description :
The HMGB1/HMG-1 Antibody from NB100-2322 is a nb100-2322 antibody to . This antibody reacts with cellular markers, chromatin research, neuroscience.
target :
HMGB1/HMG-1
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
Tris-Glycine
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human HMGB1 protein sequence (between residues 100-200). [UniProt #P09429]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat, Bovine, Canine, Rabbit, Sheep
theoretical molecular weight :
29 kDa
gene symbol :
HMGB1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Knockdown-Validated-NB100-2322-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Knockdown-Validated-NB100-2322-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunohistochemistry-Paraffin-NB100-2322-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunohistochemistry-Paraffin-NB100-2322-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Simple-Western-NB100-2322-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Simple-Western-NB100-2322-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunohistochemistry-Paraffin-NB100-2322-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunohistochemistry-Paraffin-NB100-2322-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-Cytometry-NB100-2322-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-Cytometry-NB100-2322-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Western-Blot-NB100-2322-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2322-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-(Intracellular)-NB100-2322-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-(Intracellular)-NB100-2322-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-Cytometry-NB100-2322-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-Flow-Cytometry-NB100-2322-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-ELISA-NB100-2322-img0023.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HMGB1-HMG-1-Antibody-ELISA-NB100-2322-img0023.jpg
applications :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular), Knockdown Validated
USD :
469 USD
alt names :
Amphoterin, high mobility group box 1, High mobility group protein 1, high mobility group protein B1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydrate binding protein
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.