| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry knockout validation; mouse; 1:1000; loading ...; fig 4e
- western blot knockout validation; mouse; loading ...; fig 2b
| Kim B, Kim J, Chun M, Park I, Kwak D, Choi M, et al. Multiplexed CRISPR-Cas9 system in a single adeno-associated virus to simultaneously knock out redundant clock genes. Sci Rep. 2021;11:2575 pubmed publisher |
- immunohistochemistry; mouse; 1:250; loading ...; fig 3a
| Cha S, Lee S, Wang J, Zhao Q, Bai D. Enhanced Circadian Clock in MSCs-Based Cytotherapy Ameliorates Age-Related Temporomandibular Joint Condyle Degeneration. Int J Mol Sci. 2021;22: pubmed publisher |
- chromatin immunoprecipitation; human; ; loading ...; fig 3f
- immunohistochemistry; human; 10 ug/ml; fig s5a
| Xu L, Liu Y, Cheng Q, Shen Y, Yuan Y, Jiang X, et al. Bmal1 Downregulation Worsens Critical Limb Ischemia by Promoting Inflammation and Impairing Angiogenesis. Front Cardiovasc Med. 2021;8:712903 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 2c
| Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, et al. Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A. EBioMedicine. 2019;45:139-154 pubmed publisher |
| González J, Lee H, Vincent A, Hill A, Goode L, King G, et al. Circadian regulation of dentate gyrus excitability mediated by G-protein signaling. Cell Rep. 2023;42:112039 pubmed publisher |
| Zhang C, Chen L, Sun L, Jin H, Ren K, Liu S, et al. BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance. Oncogene. 2023;42:967-979 pubmed publisher |
| Jang D, Yang B, You M, Rim C, Kim H, Sung S, et al. Fluoxetine Decreases Phagocytic Function via REV-ERBα in Microglia. Neurochem Res. 2022;: pubmed publisher |
| Singla R, Mishra A, Lin H, Lorsung E, Le N, Tin S, et al. Haploinsufficiency of a Circadian Clock Gene Bmal1 (Arntl or Mop3) Causes Brain-Wide mTOR Hyperactivation and Autism-like Behavioral Phenotypes in Mice. Int J Mol Sci. 2022;23: pubmed publisher |
| Vanmunster M, Rojo Garcia A, Pacolet A, Dalle S, Koppo K, Jonkers I, et al. Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism. Cell Mol Life Sci. 2022;79:321 pubmed publisher |
| Ye P, Li W, Huang X, Zhao S, Chen W, Xia Y, et al. BMAL1 regulates mitochondrial homeostasis in renal ischaemia-reperfusion injury by mediating the SIRT1/PGC-1α axis. J Cell Mol Med. 2022;26:1994-2009 pubmed publisher |
| McKee C, Lee J, Cai Y, Saito T, Saido T, Musiek E. Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden. Sci Rep. 2022;12:1796 pubmed publisher |
| de Zavalía N, Schoettner K, Goldsmith J, Solis P, Ferraro S, Parent G, et al. Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner. Commun Biol. 2021;4:1227 pubmed publisher |
| Gegnaw S, Sandu C, Mendoza J, Bergen A, Felder Schmittbuhl M. Dark-adapted light response in mice is regulated by a circadian clock located in rod photoreceptors. Exp Eye Res. 2021;213:108807 pubmed publisher |
| Trebucq L, Cardama G, Lorenzano Menna P, Golombek D, Chiesa J, Marpegan L. Timing of Novel Drug 1A-116 to Circadian Rhythms Improves Therapeutic Effects against Glioblastoma. Pharmaceutics. 2021;13: pubmed publisher |
| Huang W, Zheng X, Yang M, Li R, Song Y. PER2-mediated ameloblast differentiation via PPARγ/AKT1/β-catenin axis. Int J Oral Sci. 2021;13:16 pubmed publisher |
| Kim H, Wei J, Song Z, Mottillo E, Samavati L, Zhang R, et al. Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program. Mol Metab. 2021;49:101192 pubmed publisher |
| Sominsky L, Dangel T, Malik S, De Luca S, Singewald N, Spencer S. Microglial ablation in rats disrupts the circadian system. FASEB J. 2021;35:e21195 pubmed publisher |
| Wang X, Wolff S, Korpel N, Milanova I, Sandu C, Rensen P, et al. Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism. Front Immunol. 2020;11:586399 pubmed publisher |
| Greco C, Cervantes M, Fustin J, Ito K, Ceglia N, Samad M, et al. S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling. Sci Adv. 2020;6: pubmed publisher |
| Kim E, Xu Y, Cassidy R, Lu Y, Yang Y, Tian J, et al. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun. 2020;11:3794 pubmed publisher |
| La Fuente J, Sevilleja Ortiz A, García Rojo E, El Assar M, Fernández A, Pepe Cardoso A, et al. Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries. Eur J Pharmacol. 2020;884:173370 pubmed publisher |
| Chi T, Hsieh B, Liang P, Han T, Hsieh M. Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells. Cell Mol Neurobiol. 2020;: pubmed publisher |
| Beauvarlet J, Nath Das R, Alvarez Valadez K, Martins I, Muller A, Darbo E, et al. Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher |
| Khodja Y, Samuels M. Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis. Lipids Health Dis. 2020;19:144 pubmed publisher |
| Wu C, Chang C, Yang T, Tsai A, Wang J, Chang C, et al. Tubular transcriptional co-activator with PDZ-binding motif protects against ischemic acute kidney injury. Clin Sci (Lond). 2020;134:1593-1612 pubmed publisher |
| Hsieh M, Hsieh M, Lo Y, Lin C, Chuang Y, Chen M, et al. Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway. Biomed Pharmacother. 2020;128:110318 pubmed publisher |
| Alicea G, Rebecca V, Goldman A, Fane M, Douglass S, Behera R, et al. Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2. Cancer Discov. 2020;10:1282-1295 pubmed publisher |
| Marshall J, Courage E, Elliott R, Fitzpatrick M, Kim A, Lopez Clavijo A, et al. THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation. PLoS ONE. 2020;15:e0233180 pubmed publisher |
| Dan H, Ruan T, Sampogna R. Circadian Clock Regulation of Developmental Time in the Kidney. Cell Rep. 2020;31:107661 pubmed publisher |
| Oishi N, Hundal T, Phillips J, Dasari S, Hu G, Viswanatha D, et al. Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma. Haematologica. 2020;: pubmed publisher |
| Bartl S, Oueslati A, Southwell A, Siddu A, Parth M, David L, et al. Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease. Neurobiol Dis. 2020;141:104943 pubmed publisher |
| Chang Y, Ko B, Ju J, Chang H, Huang S, Lin C. SARS Unique Domain (SUD) of Severe Acute Respiratory Syndrome Coronavirus Induces NLRP3 Inflammasome-Dependent CXCL10-Mediated Pulmonary Inflammation. Int J Mol Sci. 2020;21: pubmed publisher |
| Jin Y, Shen Y, Su X, Cai J, Liu Y, Weintraub N, et al. The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells. Front Cell Dev Biol. 2020;8:209 pubmed publisher |
| Barbier V, Erbani J, Fiveash C, Davies J, Tay J, Tallack M, et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nat Commun. 2020;11:2042 pubmed publisher |
| Li R, Li X, Hagood J, Zhu M, Sun X. Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface. J Clin Invest. 2020;130:2859-2871 pubmed publisher |
| Romeo M, Gilardini Montani M, Benedetti R, Garufi A, D Orazi G, Cirone M. PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR. Biomolecules. 2020;10: pubmed publisher |
| Pei X, Kim H, Lee M, Wang N, Shin J, Lee S, et al. Local delivery of cardiac stem cells overexpressing HIF-1α promotes angiogenesis and muscular tissue repair in a hind limb ischemia model. J Control Release. 2020;322:610-621 pubmed publisher |
| Lin J, Chen S, Lu C, Lin J, Yen G. Ursolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells. Phytother Res. 2020;: pubmed publisher |
| Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span. FASEB J. 2020;34:5590-5609 pubmed publisher |
| Chen Y, Tsai C, Cheng Y, Nieh S, Yeh T, Chen C, et al. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System. Sci Rep. 2020;10:2838 pubmed publisher |
| Cheng C, Kao S, Lee Y. Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats. J Ethnopharmacol. 2020;252:112612 pubmed publisher |
| Biswas L, Zeng Z, Graham A, Shu X. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells. Exp Eye Res. 2020;191:107931 pubmed publisher |
| Lieberman O, Frier M, McGuirt A, Griffey C, Rafikian E, Yang M, et al. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. elife. 2020;9: pubmed publisher |
| Cho S, Chae J, Shin H, Shin Y, Kim Y, Kil E, et al. Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation. Transl Oncol. 2020;13:401-409 pubmed publisher |
| Rogers M, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel J, et al. Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects. Arterioscler Thromb Vasc Biol. 2020;40:656-669 pubmed publisher |
| Langley M, Yoon H, Kim H, Choi C, Simon W, Kleppe L, et al. High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165630 pubmed publisher |
| Yuan P, Yang T, Mu J, Zhao J, Yang Y, Yan Z, et al. Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cells. Cancer Lett. 2020;469:498-509 pubmed publisher |
| Arima N, Sasaki Y, Lee L, Zhang H, Figueiredo J, Mlynarchik A, et al. Multiorgan Systems Study Reveals Igfbp7 as a Suppressor of Gluconeogenesis after Gastric Bypass Surgery. J Proteome Res. 2020;19:129-143 pubmed publisher |
| Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed publisher |
| Hughes B, Crofton E, O Buckley T, Herman M, Morrow A. Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain. Neuropharmacology. 2020;162:107805 pubmed publisher |
| Wang C, Holtzman D. Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors. Neuropsychopharmacology. 2020;45:104-120 pubmed publisher |
| Alhakamy N, Md S. Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers. Pharmaceutics. 2019;11: pubmed publisher |
| Dos Santos Ortolan L, Sercundes M, Moura G, de Castro Quirino T, Debone D, de Sousa Costa D, et al. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. J Immunol Res. 2019;2019:3105817 pubmed publisher |
| Hasegawa S, Fukushima H, Hosoda H, Serita T, Ishikawa R, Rokukawa T, et al. Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation. Nat Commun. 2019;10:5766 pubmed publisher |
| Lima F, Barateiro A, Dombrowski J, de Souza R, Costa D, Murillo O, et al. Plasmodium falciparum infection dysregulates placental autophagy. PLoS ONE. 2019;14:e0226117 pubmed publisher |
| Su X, Jin Y, Shen Y, Kim I, Weintraub N, Tang Y. RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells. Int J Mol Sci. 2019;20: pubmed publisher |
| Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher |
| Herroon M, Diedrich J, Rajagurubandara E, Martin C, Maddipati K, Kim S, et al. Prostate Tumor Cell-Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms. Mol Cancer Res. 2019;17:2508-2521 pubmed publisher |
| Aladaileh S, Hussein O, Abukhalil M, Saghir S, Bin Jumah M, Alfwuaires M, et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats. Antioxidants (Basel). 2019;8: pubmed publisher |
| Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, et al. A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome. elife. 2019;8: pubmed publisher |
| Vande Walle L, Stowe I, Sácha P, Lee B, Demon D, Fossoul A, et al. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition. PLoS Biol. 2019;17:e3000354 pubmed publisher |
| Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun. 2019;10:4176 pubmed publisher |
| Su S, Hung Y, Huang C, Shieh Y, Chien C, Chiang C, et al. Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways. J Biomed Sci. 2019;26:68 pubmed publisher |
| Zhou T, Zhu T, Rivera J, Omri S, Tahiri H, Lahaie I, et al. The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity. Am J Pathol. 2019;189:2340-2356 pubmed publisher |
| Li M, Peng W, Wu C, Chang Y, Lin Y, Chang G, et al. PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization. Oncogene. 2019;38:7002-7016 pubmed publisher |
| Stroik S, Kurtz K, Hendrickson E. CtIP is essential for telomere replication. Nucleic Acids Res. 2019;47:8927-8940 pubmed publisher |
| Hao C, Liu G, Tian G. Autophagy inhibition of cancer stem cells promotes the efficacy of cisplatin against non-small cell lung carcinoma. Ther Adv Respir Dis. 2019;13:1753466619866097 pubmed publisher |
| Hayward D, Kouznetsova V, Pierson H, Hasan N, Guzman E, Tsigelny I, et al. ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly. J Biol Chem. 2019;294:14454-14466 pubmed publisher |
| Hannibal J, Norn T, Georg B, Fahrenkrug J. Spatiotemporal expression pattern of PERIOD 1 and PERIOD 2 in the mouse SCN is dependent on VIP receptor 2 signaling. Eur J Neurosci. 2019;50:3115-3132 pubmed publisher |
| Tsolou A, Lamprou I, Fortosi A, Liousia M, Giatromanolaki A, Koukourakis M. 'Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation. Life Sci. 2019;:116562 pubmed publisher |
| Wangsa D, Braun R, Stuelten C, Brown M, Bauer K, Emons G, et al. Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells. Neoplasia. 2019;21:721-729 pubmed publisher |
| Scheidecker S, Bär S, Stoetzel C, Geoffroy V, Lannes B, Rinaldi B, et al. Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy. Hum Mutat. 2019;40:1826-1840 pubmed publisher |
| Li Z, Zhang S, Li J, Zeng H, Wang Y, Huang Y. Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration. J Comp Neurol. 2019;527:2885-2895 pubmed publisher |
| Saporiti F, Piacentini L, Alfieri V, Bono E, Ferrari F, Chiesa M, et al. Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration. Cell Physiol Biochem. 2019;52:1339-1360 pubmed publisher |
| Luo Q, Xiao Y, Alex A, Cummins T, Bhatwadekar A. The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1. Invest Ophthalmol Vis Sci. 2019;60:1928-1936 pubmed publisher |
| Sakai S, Ohhata T, Kitagawa K, Uchida C, Aoshima T, Niida H, et al. Long Noncoding RNA ELIT-1 Acts as a Smad3 Cofactor to Facilitate TGFβ/Smad Signaling and Promote Epithelial-Mesenchymal Transition. Cancer Res. 2019;79:2821-2838 pubmed publisher |
| Chiba M, Ito Y, Nagasawa T. Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes. Biosci Biotechnol Biochem. 2019;83:1319-1328 pubmed publisher |
| Hughes B, Bohnsack J, O Buckley T, Herman M, Morrow A. Chronic Ethanol Exposure and Withdrawal Impair Synaptic GABAA Receptor-Mediated Neurotransmission in Deep-Layer Prefrontal Cortex. Alcohol Clin Exp Res. 2019;43:822-832 pubmed publisher |
| Wu H, Ploeger J, Kamarajugadda S, Mashek D, Mashek M, Manivel J, et al. Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes. Hepatol Commun. 2019;3:406-422 pubmed publisher |
| Lee M, Miller Z, Park J, Bhattarai D, Lee W, Kim K. H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth. Sci Rep. 2019;9:4089 pubmed publisher |
| Cedernaes J, Huang W, Ramsey K, Waldeck N, Cheng L, Marcheva B, et al. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metab. 2019;29:1078-1091.e5 pubmed publisher |
| Laitakari A, Ollonen T, Kietzmann T, Walkinshaw G, Mennerich D, Izzi V, et al. Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease. Redox Biol. 2019;22:101145 pubmed publisher |
| Ryzhikov M, Ehlers A, Steinberg D, Xie W, Oberlander E, Brown S, et al. Diurnal Rhythms Spatially and Temporally Organize Autophagy. Cell Rep. 2019;26:1880-1892.e6 pubmed publisher |
| Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, et al. Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells. Nucleic Acids Res. 2019;47:2739-2756 pubmed publisher |
| van der Waals L, Laoukili J, Jongen J, Raats D, Borel Rinkes I, Kranenburg O. Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures. Sci Rep. 2019;9:819 pubmed publisher |
| Zhang H, Wei Q, Xiang X, Zhou B, Chen J, Li J, et al. Semaphorin 4A acts in a feed-forward loop with NF-κB pathway to exacerbate catabolic effect of IL-1β on chondrocytes. Int Immunopharmacol. 2019;69:88-94 pubmed publisher |
| Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed publisher |
| Spence E, Dube S, Uezu A, Locke M, Soderblom E, Soderling S. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019;10:386 pubmed publisher |
| Even I, Reidenbach S, Schlechter T, Berns N, Herold R, Roth W, et al. DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells. FEBS J. 2019;286:803-820 pubmed publisher |
| Ye R, Onodera T, Blanchard P, Kusminski C, Esser V, Brekken R, et al. β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis. Am J Pathol. 2019;189:813-825 pubmed publisher |
| Wang B, Pan J, Yu H, Xiong L, Zhao K, Xiong S, et al. Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells. J Bone Miner Res. 2019;34:939-954 pubmed publisher |
| Lee C, Yang J, Chen C, Tsai M, Hung P, Chen S, et al. Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer. Cancers (Basel). 2019;11: pubmed publisher |
| Cheng C, Kao S, Lee Y. Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats. Am J Chin Med. 2019;47:39-61 pubmed publisher |
| Davis S, Collier L, Foran E, Leonardo C, Ajmo C, Pennypacker K. Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke. Metab Brain Dis. 2019;34:631-640 pubmed publisher |
| Chen J, Yang T, Cheng T, Hsiao T, Chang P, Leu J, et al. Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy. J Ethnopharmacol. 2019;233:47-55 pubmed publisher |
| Oh S, Sung Y, Kim I, Sim C, Lee J, Baek M, et al. Novel Compound Heterozygote Mutation in IL10RA in a Patient With Very Early-Onset Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019;25:498-509 pubmed publisher |
| Yang C, Gopula B, Liang J, Li J, Chen S, Lee Y, et al. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis. Emerg Microbes Infect. 2018;7:187 pubmed publisher |
| Davis S, Collier L, Goodwin S, Lukins D, Powell D, Pennypacker K. Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. Brain Res. 2019;1707:62-73 pubmed publisher |
| Harun Or Rashid M, Inman D. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. J Neuroinflammation. 2018;15:313 pubmed publisher |
| Zhu M, Tang H, Tang X, Ma X, Guo D, Chen F. BMAL1 suppresses ROS-induced endothelial-to-mesenchymal transition and atherosclerosis plaque progression via BMP signaling. Am J Transl Res. 2018;10:3150-3161 pubmed |
| Di K, Lomeli N, Bota D, Das B. Magmas inhibition as a potential treatment strategy in malignant glioma. J Neurooncol. 2019;141:267-276 pubmed publisher |
| Zhang C, Lai M, Pedler M, Johnson V, Adams R, Petrash J, et al. Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature. Arterioscler Thromb Vasc Biol. 2018;38:2691-2705 pubmed publisher |
| Davis S, Collier L, Winford E, Leonardo C, Ajmo C, Foran E, et al. Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion. J Neuroinflammation. 2018;15:288 pubmed publisher |
| Halu A, Wang J, Iwata H, Mojcher A, Abib A, Singh S, et al. Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation. elife. 2018;7: pubmed publisher |
| Lananna B, Nadarajah C, Izumo M, Cedeno M, Xiong D, Dimitry J, et al. Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Rep. 2018;25:1-9.e5 pubmed publisher |
| Yang C, Stueve T, Yan C, Rhie S, Mullen D, Luo J, et al. Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes. Epigenomics. 2018;10:1167-1187 pubmed publisher |
| Going C, Tailor D, Kumar V, Birk A, Pandrala M, Rice M, et al. Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer. J Proteome Res. 2018;17:3574-3585 pubmed publisher |
| Zhao K, Shen C, Li L, Wu H, Xing G, Dong Z, et al. Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. J Neurosci. 2018;38:8860-8873 pubmed publisher |
| Lee B, Stowe I, Gupta A, Kornfeld O, Roose Girma M, Anderson K, et al. Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation. J Exp Med. 2018;215:2279-2288 pubmed publisher |
| Vicente M, Almeida M, Bicego K, Carrettiero D, Gargaglioni L. Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats. J Alzheimers Dis. 2018;65:1159-1174 pubmed publisher |
| Li Z, Qian P, Shao W, Shi H, He X, Gogol M, et al. Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018;28:904-917 pubmed publisher |
| Lieberman O, McGuirt A, Mosharov E, Pigulevskiy I, Hobson B, Choi S, et al. Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period. Neuron. 2018;99:540-554.e4 pubmed publisher |
| Benhadjeba S, Edjekouane L, Sauvé K, Carmona E, Tremblay A. Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer. Mol Oncol. 2018;12:1689-1705 pubmed publisher |
| Chiu H, Chiu H, Yang C, Lee Y, Chiu F, Kuo H, et al. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathog. 2018;14:e1007166 pubmed publisher |
| Laukka T, Myllykoski M, Looper R, Koivunen P. Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases. J Mol Biol. 2018;430:3081-3092 pubmed publisher |
| Li T, Wu Y, Tsai H, Sun C, Wu Y, Wu H, et al. Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. J Pathol. 2018;245:502-513 pubmed publisher |
| Motzko Soares A, Vizin R, Martins T, Hungaro A, Sato J, Almeida M, et al. Thermoregulatory profile of neurodegeneration-induced dementia of the Alzheimer's type using intracerebroventricular streptozotocin in rats. Acta Physiol (Oxf). 2018;224:e13084 pubmed publisher |
| Maddalena A, Dell Aquila F, Giovannelli P, Tiberi P, Wanderlingh L, Montefusco S, et al. High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina. Hum Gene Ther. 2018;29:886-901 pubmed publisher |
| Zhou R, Xu T, Liu X, Chen Y, Kong D, Tian H, et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain. J Pain Res. 2018;11:615-628 pubmed publisher |
| Ferriero R, Nusco E, De Cegli R, Carissimo A, Manco G, Brunetti Pierri N. Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure. J Hepatol. 2018;69:325-335 pubmed publisher |
| Tsai M, Wang Y, Lai Y, Tsou H, Liou G, Ko J, et al. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. Toxicol Lett. 2018;290:97-109 pubmed publisher |
| Lee B, Mirrashidi K, Stowe I, Kummerfeld S, Watanabe C, Haley B, et al. ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages. Sci Rep. 2018;8:3788 pubmed publisher |
| Das V, Kc R, Li X, Varma D, Qiu S, Kroin J, et al. Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain. Gene. 2018;655:1-12 pubmed publisher |
| Steiner C, Gevaert T, Ganzer R, De Ridder D, Neuhaus J. Comparative immunohistochemical characterization of interstitial cells in the urinary bladder of human, guinea pig and pig. Histochem Cell Biol. 2018;149:491-501 pubmed publisher |
| Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, et al. Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. J Clin Invest. 2018;128:1178-1189 pubmed publisher |
| Itoh S, Mizuno K, Aikawa M, Aikawa E. Dimerization of sortilin regulates its trafficking to extracellular vesicles. J Biol Chem. 2018;293:4532-4544 pubmed publisher |
| Kress G, Liao F, Dimitry J, Cedeno M, Fitzgerald G, Holtzman D, et al. Regulation of amyloid-β dynamics and pathology by the circadian clock. J Exp Med. 2018;215:1059-1068 pubmed publisher |
| Yu X, Stallone J, Heaps C, Han G. The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. PLoS ONE. 2018;13:e0191418 pubmed publisher |
| Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, et al. Triple Vectors Expand AAV Transfer Capacity in the Retina. Mol Ther. 2018;26:524-541 pubmed publisher |
| Nag S, Resnick A. Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport. Physiol Rep. 2017;5: pubmed publisher |
| Pol A, Renkema G, Tangerman A, Winkel E, Engelke U, de Brouwer A, et al. Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Nat Genet. 2018;50:120-129 pubmed publisher |
| Cree B, Niu J, Hoi K, Zhao C, Caganap S, Henry R, et al. Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain. 2017;: pubmed publisher |
| Boström J, Srámková Z, Salasova A, Johard H, Mahdessian D, Fedr R, et al. Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells. PLoS ONE. 2017;12:e0188772 pubmed publisher |
| Ullah K, Rosendahl A, Izzi V, Bergmann U, Pihlajaniemi T, Maki J, et al. Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways. Sci Rep. 2017;7:17220 pubmed publisher |
| Khan N, Muralidharan A, Smith M. Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Recepto. Front Mol Neurosci. 2017;10:389 pubmed publisher |
| Jongen J, van der Waals L, Trumpi K, Laoukili J, Peters N, Schenning van Schelven S, et al. Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability. Oncotarget. 2017;8:86296-86311 pubmed publisher |
| Mazzoni J, Smith J, Shahriar S, Cutforth T, Ceja B, Agalliu D. The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels. Neuron. 2017;96:1055-1069.e6 pubmed publisher |
| Ge Q, Zhang H, Hou J, Wan L, Cheng W, Wang X, et al. VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms. Mol Med Rep. 2017;: pubmed publisher |
| Lai B, Zou J, Lin Z, Qu Z, Song A, Xu Y, et al. Haploinsufficiency of hnRNP U Changes Activity Pattern and Metabolic Rhythms. Am J Pathol. 2018;188:173-183 pubmed publisher |
| El Hassan A, Leung V, Kharfallah F, Guyot M, Allache R, Gros P, et al. Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mamm Genome. 2018;29:229-244 pubmed publisher |
| Zhao W, Pferdehirt L, Segatori L. Quantitatively Predictable Control of Cellular Protein Levels through Proteasomal Degradation. ACS Synth Biol. 2017;: pubmed publisher |
| Walters D, Arendt B, Tschumper R, Wu X, Jelinek D. Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain. Exp Hematol. 2018;57:42-49.e1 pubmed publisher |
| Yoon H, Radulovic M, Walters G, Paulsen A, Drucker K, Starski P, et al. Protease activated receptor 2 controls myelin development, resiliency and repair. Glia. 2017;65:2070-2086 pubmed publisher |
| Niu J, Huang D, Zhou R, Yue M, Xu T, Yang J, et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats. J Neuroinflammation. 2017;14:185 pubmed publisher |
| Nagami M, Ito Y, Nagasawa T. Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes. Biosci Biotechnol Biochem. 2017;81:2195-2203 pubmed publisher |
| Chiu H, Tsay Y, Hung S. Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture. Sci Rep. 2017;7:10113 pubmed publisher |
| Bohnsack J, Patel V, Morrow A. Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons. J Pharmacol Exp Ther. 2017;363:1-11 pubmed publisher |
| Noutsios G, Willis A, Ledford J, Chang E. Novel role of surfactant protein A in bacterial sinusitis. Int Forum Allergy Rhinol. 2017;7:897-903 pubmed publisher |
| Lin N, Messing A, Perng M. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP. PLoS ONE. 2017;12:e0180694 pubmed publisher |
| Yoon H, Walters G, Paulsen A, Scarisbrick I. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PLoS ONE. 2017;12:e0180697 pubmed publisher |
| Ambroz M, Matousková P, Skarka A, Zajdlova M, Žáková K, Skalova L. The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines. Molecules. 2017;22: pubmed publisher |
| Chang C, Lu C, Lin C, Martel J, Ko Y, Ojcius D, et al. Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. Int J Obes (Lond). 2018;42:231-243 pubmed publisher |
| Zagni C, Almeida L, Balan T, Martins M, Rosselli Murai L, Papagerakis P, et al. PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells. Stem Cell Reports. 2017;9:304-314 pubmed publisher |
| Wu P, Wang J, Chen C, Chao K, Chang M, Chen W, et al. Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity. Stem Cells Transl Med. 2017;6:1504-1514 pubmed publisher |
| Balbaa M, Abdulmalek S, Khalil S. Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs. PLoS ONE. 2017;12:e0172429 pubmed publisher |
| Pettersson H, Zarnegar B, Westin A, Persson V, Peuckert C, Jönsson J, et al. SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo. Sci Rep. 2017;7:1085 pubmed publisher |
| Frederick A, Goldsmith J, de Zavalía N, Amir S. Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain. PLoS ONE. 2017;12:e0176279 pubmed publisher |
| Wang X, Dasari S, Nowakowski G, Lazaridis K, Wieben E, Kadin M, et al. Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma. Oncotarget. 2017;8:26245-26255 pubmed publisher |
| Ho T, Lee C, Lu Z, Lane H, Tsai M, Ho I, et al. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evid Based Complement Alternat Med. 2017;2017:5642708 pubmed publisher |
| Lee Y, Kim J, Oh K, Chung S. Fatty acid-binding protein 4 regulates fatty infiltration after rotator cuff tear by hypoxia-inducible factor 1 in mice. J Cachexia Sarcopenia Muscle. 2017;8:839-850 pubmed publisher |
| Raats D, Frenkel N, van Schelven S, Rinkes I, Laoukili J, Kranenburg O. CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage. Cell Death Dis. 2017;8:e2669 pubmed publisher |
| Piccolo P, Annunziata P, Soria L, Attanasio S, Barbato A, Castello R, et al. Down-regulation of hepatocyte nuclear factor-4? and defective zonation in livers expressing mutant Z ?1-antitrypsin. Hepatology. 2017;66:124-135 pubmed publisher |
| Chen K, Hsieh M, Li Y, Lin Y, Lai H, Shieh M, et al. Study of poly-?-caprolactone membranes for pleurodesis. J Formos Med Assoc. 2017;116:880-887 pubmed publisher |
| Bilodeau S, Caron V, Gagnon J, Kuftedjian A, Tremblay A. A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR. J Mol Cell Biol. 2017;9:195-208 pubmed publisher |
| Giatromanolaki A, Liousia M, Arelaki S, Kalamida D, Pouliliou S, Mitrakas A, et al. Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism. Biochem Cell Biol. 2017;95:428-436 pubmed publisher |
| Wang X, Boddicker R, Dasari S, Sidhu J, Kadin M, Macon W, et al. Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping. Hum Pathol. 2017;64:19-27 pubmed publisher |
| Sansone C, Galasso C, Orefice I, Nuzzo G, Luongo E, Cutignano A, et al. The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells. Sci Rep. 2017;7:41215 pubmed publisher |
| Pereira M, Ortolan L, Sercundes M, Debone D, Murillo O, Lima F, et al. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS. Mediators Inflamm. 2016;2016:4158698 pubmed |
| Abdelbaset Ismail A, Pędziwiatr D, Schneider G, Niklinski J, Charkiewicz R, Moniuszko M, et al. Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1. Int J Oncol. 2017;50:317-328 pubmed publisher |
| Lin Y, Chao T, Yeh C, Roffler S, Kannagi R, Yang R. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis. Arterioscler Thromb Vasc Biol. 2017;37:144-155 pubmed publisher |
| Chen H, Yeh Y, Liu C, Wu Y, Lo F, Tang M, et al. DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis. Sci Rep. 2016;6:36336 pubmed publisher |
| Getun I, Wu Z, Fallahi M, Ouizem S, Liu Q, Li W, et al. Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots. Mol Cell Biol. 2017;37: pubmed publisher |
| Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh W, Halu A, et al. PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation. Nat Commun. 2016;7:12849 pubmed publisher |
| Zhou T, Rivera J, Bhosle V, Lahaie I, Shao Z, Tahiri H, et al. Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1?. Am J Pathol. 2016;186:3100-3116 pubmed publisher |
| Di K, Lomeli N, Wood S, Vanderwal C, Bota D. Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma. Oncotarget. 2016;7:77457-77467 pubmed publisher |
| Pradhan S, Mahajan D, Kaur P, Pandey N, Sharma C, Srivastava T. Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells. Oncotarget. 2016;7:71841-71855 pubmed publisher |
| Dumbell R, Leliavski A, Matveeva O, Blaum C, Tsang A, Oster H. Dissociation of Molecular and Endocrine Circadian Rhythms in Male Mice Lacking Bmal1 in the Adrenal Cortex. Endocrinology. 2016;157:4222-4233 pubmed |
| Hu Y, Su H, Liu C, Wang Z, Huang L, Wang Q, et al. DEPTOR is a direct NOTCH1 target that promotes cell proliferation and survival in T-cell leukemia. Oncogene. 2017;36:1038-1047 pubmed publisher |
| Erdogan S, Doganlar O, Doganlar Z, Serttas R, Türkekul K, Dibirdik I, et al. The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-?B signaling. Life Sci. 2016;162:77-86 pubmed publisher |
| Yoon H, Scarisbrick I. Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis. Biol Chem. 2016;397:1277-1286 pubmed publisher |
| Vanas V, Haigl B, Stockhammer V, Sutterlüty Fall H. MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells. PLoS ONE. 2016;11:e0161023 pubmed publisher |
| Leinonen H, Rossi M, Salo A, Tiainen P, Hyvärinen J, Pitkänen M, et al. Lack of P4H-TM in mice results in age-related retinal and renal alterations. Hum Mol Genet. 2016;25:3810-3823 pubmed publisher |
| Sato T, Ito Y, Nagasawa T. Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes. Biosci Biotechnol Biochem. 2016;80:2168-2175 pubmed publisher |
| Wong A, Hristova E, Ahlskog N, Tasse L, Ngsee J, Chudalayandi P, et al. Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases. Mol Pharmacol. 2016;90:238-53 pubmed publisher |
| Ekser B, Mangus R, Kubal C, Fridell J, Powelson J, Nagaraju S, et al. Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria. Am J Nephrol. 2016;44:85-91 pubmed publisher |
| Baradaran Heravi A, Balgi A, Zimmerman C, Choi K, Shidmoossavee F, Tan J, et al. Novel small molecules potentiate premature termination codon readthrough by aminoglycosides. Nucleic Acids Res. 2016;44:6583-98 pubmed publisher |
| Lee M, Huang H, Chang T, Huang H, Hsieh S, Chen Y, et al. Genome-wide analysis of HIF-2? chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions. Sci Rep. 2016;6:29311 pubmed publisher |
| Xu Y, Li F, Zalzala M, Xu J, Gonzalez F, Adorini L, et al. Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice. Hepatology. 2016;64:1072-85 pubmed publisher |
| Goettsch C, Hutcheson J, Hagita S, Rogers M, Creager M, Pham T, et al. A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis. 2016;251:109-118 pubmed publisher |
| Matsumoto C, Almeida L, Guimarães D, Martins M, Papagerakis P, Papagerakis S, et al. PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells. Oncotarget. 2016;7:42393-42407 pubmed publisher |
| Tsai W, Yeh P, Tsai C, Ting C, Chiu Y, Tao M, et al. Efficient programming of human mesenchymal stem cell-derived hepatocytes by epigenetic regulations. J Gastroenterol Hepatol. 2017;32:261-269 pubmed publisher |
| Bhoopathi P, Lee N, Pradhan A, Shen X, Das S, Sarkar D, et al. mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM. Cancer Res. 2016;76:3572-82 pubmed publisher |
| Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed publisher |
| Radulovic M, Yoon H, Wu J, Mustafa K, Scarisbrick I. Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. Neurobiol Dis. 2016;93:226-42 pubmed publisher |
| Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed publisher |
| Lai C, Chen H, Tsai T, Chu T, Yang S, Chong K, et al. Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling. Sci Rep. 2016;6:24023 pubmed publisher |
| Xu J, Xu Y, Li Y, Jadhav K, You M, Yin L, et al. Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4? and Protects Against Alcohol- and MCD diet-induced Liver Injury. Sci Rep. 2016;6:24277 pubmed publisher |
| Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed publisher |
| Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher |
| Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher |
| Andreev E, Brosseau N, Carmona E, Mes Masson A, Ramotar D. The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin. Sci Rep. 2016;6:20508 pubmed publisher |
| Gosejacob D, Jäger P, Vom Dorp K, Frejno M, Carstensen A, Köhnke M, et al. Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity. J Biol Chem. 2016;291:6989-7003 pubmed publisher |
| Yoon H, Kleven A, Paulsen A, Kleppe L, Wu J, Ying Z, et al. Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system. Biochim Biophys Acta. 2016;1862:545-555 pubmed publisher |
| Maj M, Hoermann G, Rasul S, Base W, Wagner L, Attems J. The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells. J Diabetes Res. 2016;2016:1964634 pubmed publisher |
| Westwell Roper C, Denroche H, Ehses J, Verchere C. Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates. J Biol Chem. 2016;291:8908-17 pubmed publisher |
| Bohnsack J, Carlson S, Morrow A. Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons. Neuropharmacology. 2016;105:124-132 pubmed publisher |
| Davis S, Collier L, Leonardo C, Seifert H, Ajmo C, Pennypacker K. Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3. Mol Neurobiol. 2017;54:608-622 pubmed publisher |
| Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher |
| Cerqueira F, Chausse B, Baranovski B, Liesa M, Lewis E, Shirihai O, et al. Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity. FEBS J. 2016;283:822-33 pubmed publisher |
| Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed publisher |
| Kral R, Doriguzzi A, Mayer C, Krenbek D, Setinek U, Sutterlüty Fall H. Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells. J Cell Biochem. 2016;117:1822-32 pubmed publisher |
| Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed publisher |
| Wang T, Lin Y, Lo C, Tang C, Teng C, Chao W, et al. Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells. Tumour Biol. 2016;37:7989-8005 pubmed publisher |
| Laukka T, Mariani C, Ihantola T, Cao J, Hokkanen J, Kaelin W, et al. Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes. J Biol Chem. 2016;291:4256-65 pubmed publisher |
| Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J Cell Physiol. 2016;231:1913-31 pubmed publisher |
| Sorrentino N, Maffia V, Strollo S, Cacace V, Romagnoli N, Manfredi A, et al. A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs. Mol Ther. 2016;24:276-286 pubmed publisher |
| Suriben R, Kaihara K, Paolino M, Reichelt M, Kummerfeld S, Modrusan Z, et al. β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1. Cell. 2015;163:1457-67 pubmed publisher |
| Yang Y, Jin Y, Du W. Programmed cell death 2 functions as a tumor suppressor in osteosarcoma. Int J Clin Exp Pathol. 2015;8:10894-900 pubmed |
| Fossati S, Giannoni P, Solesio M, Cocklin S, Cabrera E, Ghiso J, et al. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiol Dis. 2016;86:29-40 pubmed publisher |
| Cheng Y, Young G, Lin J, Jang H, Chen C, Nong J, et al. Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells. PLoS ONE. 2015;10:e0142283 pubmed publisher |
| Perelis M, Marcheva B, Ramsey K, Schipma M, Hutchison A, Taguchi A, et al. Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science. 2015;350:aac4250 pubmed publisher |
| Lin C, Cheng Y, Li H, Chiu P, Chang Y, Ho Y, et al. Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity. Exp Neurol. 2016;275 Pt 1:84-98 pubmed publisher |
| Lin C, Chen Y, Lin C, Chen Y, Lo G, Lee P, et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015;5:15807 pubmed publisher |
| Weng W, Leung W, Pang Y, Hsu H. Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression. Oncol Rep. 2016;35:107-16 pubmed publisher |
| Karsikas S, Myllymäki M, Heikkilä M, Sormunen R, Kivirikko K, Myllyharju J, et al. HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury. J Mol Med (Berl). 2016;94:301-10 pubmed publisher |
| Shi C, Huang X, Zhang B, Zhu D, Luo H, Lu Q, et al. The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein. PLoS ONE. 2015;10:e0138936 pubmed publisher |
| Qiu Q, Yang C, Xiong W, Tahiri H, Payeur M, Superstein R, et al. SYK is a target of lymphocyte-derived microparticles in the induction of apoptosis of human retinoblastoma cells. Apoptosis. 2015;20:1613-22 pubmed publisher |
| Cox J, Abdelrahman Y, Peters J, Naher N, Belland R. Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth. Cell Microbiol. 2016;18:305-18 pubmed publisher |
| Koukourakis M, Kalamida D, Giatromanolaki A, Zois C, Sivridis E, Pouliliou S, et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS ONE. 2015;10:e0137675 pubmed publisher |
| Sato T, Ito Y, Nagasawa T. Dietary L-Lysine Suppresses Autophagic Proteolysis and Stimulates Akt/mTOR Signaling in the Skeletal Muscle of Rats Fed a Low-Protein Diet. J Agric Food Chem. 2015;63:8192-8 pubmed publisher |
| Wu L, Zhang Z, Pan X, Wang Z. Expression and contribution of the HIF-1α/VEGF signaling pathway to luteal development and function in pregnant rats. Mol Med Rep. 2015;12:7153-9 pubmed publisher |
| Radulovic M, Yoon H, Wu J, Mustafa K, Fehlings M, Scarisbrick I. Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury. Neurobiol Dis. 2015;83:75-89 pubmed publisher |
| Sato T, Ito Y, Nagasawa T. Attenuation of autophagic-proteolysis in C2C12 cells by saccharopine. Mol Cell Biochem. 2015;410:93-100 pubmed publisher |
| Lin C, Huang W, Li H, Huang C, Hsieh S, Lai C, et al. Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. Chem Biol Interact. 2015;240:12-21 pubmed publisher |
| Juhász T, Szentléleky E, Somogyi C, Takács R, Dobrosi N, Engler M, et al. Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures. Int J Mol Sci. 2015;16:17344-67 pubmed publisher |
| Lim G, Albrecht T, Piske M, Sarai K, Lee J, Ramshaw H, et al. 14-3-3ζ coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671 pubmed publisher |
| Bamidele A, Kremer K, Hirsova P, Clift I, Gores G, Billadeau D, et al. IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes. J Cell Biol. 2015;210:257-72 pubmed publisher |
| Lin C, Jan M, Kuo J. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. 2015;12:2858-68 pubmed publisher |
| Yang C, Fischer Kešo R, Schlechter T, Ströbel P, Marx A, Hofmann I. Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression. Tumour Biol. 2015;36:9567-77 pubmed publisher |
| Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, et al. Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance. PLoS ONE. 2015;10:e0131176 pubmed publisher |
| Yang J, Lin C, Chuang C, Su S, Lin S, Yang S. Carbonic anhydrase IX overexpression regulates the migration and progression in oral squamous cell carcinoma. Tumour Biol. 2015;36:9517-24 pubmed publisher |
| Smith B, Simpson D, Miller R, Erdman J, O Brien W. Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta. J Ultrasound Med. 2015;34:1209-16 pubmed publisher |
| Miki Y, Akimoto J, Moritake K, Hironaka C, Fujiwara Y. Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells. Lasers Med Sci. 2015;30:1739-45 pubmed publisher |
| Chang C, Lin C, Lu C, Martel J, Ko Y, Ojcius D, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun. 2015;6:7489 pubmed publisher |
| Xu Y, Zalzala M, Xu J, Li Y, Yin L, Zhang Y. A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism. Nat Commun. 2015;6:7466 pubmed publisher |
| Billeter A, Galbraith N, Walker S, Lawson C, Gardner S, Sarojini H, et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response. Surgery. 2015;158:646-54 pubmed publisher |
| Viale Bouroncle S, Klingelhöffer C, Ettl T, Morsczeck C. The AKT signaling pathway sustains the osteogenic differentiation in human dental follicle cells. Mol Cell Biochem. 2015;406:199-204 pubmed publisher |
| Zhang Z, Pang X, Tang Z, Yin D, Wang Z. Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells. Mol Med Rep. 2015;12:3809-3814 pubmed publisher |
| Li H, Lu F, Hung H, Liu G, Lai T, Lin C. Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells. Int J Mol Sci. 2015;16:10426-42 pubmed publisher |
| Doriguzzi A, Haigl B, Gsur A, Sutterlüty Fall H. The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1. Int J Biochem Cell Biol. 2015;64:220-8 pubmed publisher |
| Wang M, Lin S, Hou Y, Chen Y. α-Naphthoflavone Increases Lipid Accumulation in Mature Adipocytes and Enhances Adipocyte-Stimulated Endothelial Tube Formation. Nutrients. 2015;7:3166-83 pubmed publisher |
| Yen J, Lin L, Chen M, Sarang Z, Leong P, Chang I, et al. The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1. Arthritis Res Ther. 2015;17:65 pubmed publisher |
| Kao Y, Chang B, Liang J, Tsai H, Lee Y, Lin R, et al. Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid β-oxidation. PLoS Pathog. 2015;11:e1004750 pubmed publisher |
| Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed publisher |
| Matteucci C, Minutolo A, Marino Merlo F, Grelli S, Frezza C, Mastino A, et al. Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB. Life Sci. 2015;127:90-7 pubmed publisher |
| Wen J, Hanna C, Martell S, Leung P, Lewis S, Robinson W, et al. Functional consequences of copy number variants in miscarriage. Mol Cytogenet. 2015;8:6 pubmed publisher |
| Capo Chichi J, Boissel S, Brustein E, Pickles S, Fallet Bianco C, Nassif C, et al. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J Med Genet. 2015;52:303-11 pubmed publisher |
| Yoon H, Radulovic M, Drucker K, Wu J, Scarisbrick I. The thrombin receptor is a critical extracellular switch controlling myelination. Glia. 2015;63:846-59 pubmed publisher |
| Chong K, Hsu C, Hung T, Hu H, Huang T, Wang T, et al. Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells. Cancer Biol Ther. 2015;16:149-59 pubmed publisher |
| Peng C, Lin Y, Chen K, Chyau C, Peng R. Antrodan, a β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia. Food Funct. 2015;6:635-45 pubmed publisher |
| Taher C, Frisk G, Fuentes S, Religa P, Costa H, Assinger A, et al. High prevalence of human cytomegalovirus in brain metastases of patients with primary breast and colorectal cancers. Transl Oncol. 2014;7:732-40 pubmed publisher |
| Lin S, Chiu F, Wang Y, Yen M, Kao S, Hung S. RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells. Stem Cell Reports. 2014;3:975-86 pubmed publisher |
| Hsin C, Chen M, Tang C, Lin H, Chou M, Lin C, et al. High level of plasma matrix metalloproteinase-11 is associated with clinicopathological characteristics in patients with oral squamous cell carcinoma. PLoS ONE. 2014;9:e113129 pubmed publisher |
| Pan W, Chen Y, Hsu H, Chen W. Antimicrobial peptide GW-H1-induced apoptosis of human gastric cancer AGS cell line is enhanced by suppression of autophagy. Mol Cell Biochem. 2015;400:77-86 pubmed publisher |
| Liu Y, Shim E, Crespo Mejias Y, Nguyen P, Gibbons A, Liu D, et al. Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α. Cardiovasc Toxicol. 2015;15:224-31 pubmed publisher |
| Chan M, Lim G, Skovsø S, Yang Y, Albrecht T, Alejandro E, et al. Effects of insulin on human pancreatic cancer progression modeled in vitro. BMC Cancer. 2014;14:814 pubmed publisher |
| Lajud S, Nagda D, Yamashita T, Zheng J, Tanaka N, Abuzeid W, et al. Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer. Clin Cancer Res. 2014;20:6465-78 pubmed publisher |
| Kokontis J, Lin H, Jiang S, Lin C, Fukuchi J, Hiipakka R, et al. Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2. PLoS ONE. 2014;9:e109170 pubmed publisher |
| Fischer Kešo R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, et al. Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins. Mol Cell Biol. 2014;34:4244-56 pubmed publisher |
| Naik E, Webster J, DeVoss J, Liu J, Suriben R, Dixit V. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp Med. 2014;211:1947-55 pubmed publisher |
| Qin Q, Xie H, Wise S, Browning C, Thompson K, Holmes A, et al. Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells. Toxicol Sci. 2014;142:117-25 pubmed publisher |
| Yang N, Song T, Chang Y, Chen M, Hu M. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells. Biogerontology. 2015;16:31-42 pubmed publisher |
| Hung Y, Hung S, Wu Y, Wong L, Lai M, Shih Y, et al. Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain Behav Immun. 2015;43:118-29 pubmed publisher |
| Dill McFarland K, Neil K, Zeng A, Sprenger R, Kurtz C, Suen G, et al. Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defence in the gut of 13-lined ground squirrels. Mol Ecol. 2014;23:4658-69 pubmed publisher |
| Di K, Keir S, Alexandru Abrams D, Gong X, Nguyen H, Friedman H, et al. Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models. J Neurooncol. 2014;120:473-81 pubmed publisher |
| Benayoun B, Pollina E, Ucar D, Mahmoudi S, Karra K, Wong E, et al. H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell. 2014;158:673-88 pubmed publisher |
| Lin C, Jan M, Kuo J. Autophagy-related gene expression analysis of wild-type and atg5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine. Mol Pharm. 2014;11:3002-8 pubmed publisher |
| Bohr M, Brooks A, Kurtz C. Hibernation induces immune changes in the lung of 13-lined ground squirrels (Ictidomys tridecemlineatus). Dev Comp Immunol. 2014;47:178-84 pubmed publisher |
| Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature. 2014;512:69-73 pubmed publisher |
| Chen C, Lin J, Cheng Y, Kuo C, Huang C, Kao S, et al. Amelioration of LPS-induced inflammation response in microglia by AMPK activation. Biomed Res Int. 2014;2014:692061 pubmed publisher |
| Wu C, Lin K, Teng C, Huang A, Chen Y, Yen M, et al. Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells. Biol Pharm Bull. 2014;37:1191-8 pubmed |
| Lin K, Huang A, Lin C, Chang C, Hsu W, Hour T, et al. Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer. Eur J Pharmacol. 2014;740:742-51 pubmed publisher |
| Chung P, Chi L, Chen C, Liang C, Lin C, Chang Y, et al. MicroRNA-205 targets tight junction-related proteins during urothelial cellular differentiation. Mol Cell Proteomics. 2014;13:2321-36 pubmed publisher |
| Rahtu Korpela L, Karsikas S, Horkko S, Blanco Sequeiros R, Lammentausta E, Mäkelä K, et al. HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction. Diabetes. 2014;63:3324-33 pubmed publisher |
| Press T, Viale Bouroncle S, Felthaus O, Gosau M, Morsczeck C. EGR1 supports the osteogenic differentiation of dental stem cells. Int Endod J. 2015;48:185-92 pubmed publisher |
| Zeng W, Guo Y, Qi W, Chen J, Yang L, Luo Z, et al. 4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum. Life Sci. 2014;103:15-24 pubmed publisher |
| Brugger D, Buffler M, Windisch W. Development of an experimental model to assess the bioavailability of zinc in practical piglet diets. Arch Anim Nutr. 2014;68:73-92 pubmed publisher |
| Wong T, Doyle A, Lee J, Jelinek D. Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol. 2014;192:3548-58 pubmed publisher |
| Cai B, Xie S, Liu F, Simone L, Caplan S, Qin X, et al. Rapid degradation of the complement regulator, CD59, by a novel inhibitor. J Biol Chem. 2014;289:12109-25 pubmed publisher |
| Liu Y, Shim E, Nguyen P, Gibbons A, Mitchell J, Poirier M. Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity. Toxicol Sci. 2014;139:133-41 pubmed publisher |
| Hung T, Ho C, Liu Y, Lee J, Liao Y, Wu Y, et al. Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma. PLoS ONE. 2014;9:e89446 pubmed publisher |
| Zheng X, Heaps C, Fisher S. Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion. Microvasc Res. 2015;98:166-71 pubmed publisher |
| Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti T, Lamkanfi M. Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun. 2014;5:3209 pubmed publisher |
| Liang J, Wei J, Lee Y, Hsu S, Lin J, Lin Y. Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum. J Virol. 2014;88:4218-28 pubmed publisher |
| Yu C, Yu C. Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. PLoS ONE. 2014;9:e87129 pubmed publisher |
| D souza A, Asadi A, Johnson J, Covey S, Kieffer T. Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology. 2014;155:1268-79 pubmed publisher |
| Kaczmarek M, Holland R, Lavanier S, Troxler J, Fesenkova V, Hanson C, et al. Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells. Leuk Res. 2014;38:377-82 pubmed publisher |
| Li K, Yu Y, Zhou C, Kim D, Lin B, Sharp K, et al. Calcium channel ?2?1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis. J Biol Chem. 2014;289:7025-37 pubmed publisher |
| Lin H, Lin C, Hsiao P, Wang H, Jiang S, Hsu J, et al. Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells. PLoS ONE. 2013;8:e82625 pubmed publisher |
| Zhu M, Guo M, Fei L, Pan X, Liu Q. 4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in rats with streptozotocin-induced diabetes. Endocrine. 2014;47:129-37 pubmed publisher |
| Mounce B, Mboko W, Kanack A, Tarakanova V. Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. J Virol. 2014;88:2268-78 pubmed publisher |
| Viale Bouroncle S, Gosau M, Morsczeck C. NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells. Biochem Biophys Res Commun. 2014;443:500-4 pubmed publisher |
| Schusser B, Yi H, COLLARINI E, Izquierdo S, Harriman W, Etches R, et al. Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire. PLoS ONE. 2013;8:e80108 pubmed publisher |
| Govaert K, Emmink B, Nijkamp M, Cheung Z, Steller E, Fatrai S, et al. Hypoxia after liver surgery imposes an aggressive cancer stem cell phenotype on residual tumor cells. Ann Surg. 2014;259:750-9 pubmed publisher |
| Allache R, Lachance S, Guyot M, De Marco P, Merello E, Justice M, et al. Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway. Hum Mol Genet. 2014;23:1687-99 pubmed publisher |
| Zhou C, Luo Z. Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein. Eur J Pain. 2014;18:649-58 pubmed publisher |
| Thies H, Nolte I, Wenk H, Mertens F, Bullerdiek J, Markowski D. Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue. Obesity (Silver Spring). 2014;22:141-50 pubmed publisher |
| Xu J, Li Y, Chen W, Xu Y, Yin L, Ge X, et al. Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis. Hepatology. 2014;59:1761-1771 pubmed publisher |
| Gini B, Zanca C, Guo D, Matsutani T, Masui K, Ikegami S, et al. The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res. 2013;19:5722-32 pubmed publisher |
| Li K, Kim D, Zaucke F, Luo Z. Trigeminal nerve injury-induced thrombospondin-4 up-regulation contributes to orofacial neuropathic pain states in a rat model. Eur J Pain. 2014;18:489-95 pubmed publisher |
| Snoeren N, Emmink B, Koerkamp M, van Hooff S, Goos J, van Houdt W, et al. Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer. Br J Cancer. 2013;109:1636-47 pubmed publisher |
| Feldman A, Vasmatzis G, Asmann Y, Davila J, Middha S, Eckloff B, et al. Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma. Genes Chromosomes Cancer. 2013;52:1097-102 pubmed publisher |
| Chan C, Lee K, Huang Y, Chou C, Lin H, Lee F. Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury. J Gastroenterol Hepatol. 2014;29:603-13 pubmed publisher |
| Khan Z, Yaiw K, Wilhelmi V, Lam H, Rahbar A, Stragliotto G, et al. Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis. Carcinogenesis. 2014;35:145-54 pubmed publisher |
| Liu L, Martin R, Kohler G, Chan C. Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes. Exp Neurol. 2013;248:482-90 pubmed publisher |
| Chang K, Wang C, Kao H, Liang Y, Liu S, Huang L, et al. Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma. Cancer. 2013;119:4003-11 pubmed publisher |
| Hsu P, Chen H, Yeh Y, Yen C, Wu Y, Hsu C, et al. TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma. J Gastroenterol. 2014;49:1231-40 pubmed publisher |
| Lee C, Lai Y, Chang H, Liao J, Shyu W, Li C, et al. Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma. Biochem Pharmacol. 2013;86:940-9 pubmed publisher |
| Yeh C, Chiang K, Juang H, S Pang J, Yu C, Lin K, et al. Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma. PLoS ONE. 2013;8:e69928 pubmed publisher |
| Hsieh Y, Chou M, Chen H, Tseng J. IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. Gynecol Oncol. 2013;131:182-90 pubmed publisher |
| Morel E, Chamoun Z, Lasiecka Z, Chan R, Williamson R, Vetanovetz C, et al. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun. 2013;4:2250 pubmed publisher |
| Tigrine C, Bulzomi P, Leone S, Bouriche H, Kameli A, Marino M. Cleome arabica leaf extract has anticancer properties in human cancer cells. Pharm Biol. 2013;51:1508-14 pubmed publisher |
| Wen J, Lopes F, Soares G, Farrell S, Nelson C, Qiao Y, et al. Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2. Orphanet J Rare Dis. 2013;8:100 pubmed publisher |
| Emmink B, Verheem A, van Houdt W, Steller E, Govaert K, Pham T, et al. The secretome of colon cancer stem cells contains drug-metabolizing enzymes. J Proteomics. 2013;91:84-96 pubmed publisher |
| Rathmanner N, Haigl B, Vanas V, Doriguzzi A, Gsur A, Sutterlüty Fall H. Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells. FEBS Lett. 2013;587:2597-605 pubmed publisher |
| Kremer K, Peterson K, Schneider P, Meng X, Dai H, Hess A, et al. CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem. 2013;288:22899-914 pubmed publisher |
| Ko C, Cheng C, Lai C, Tzu T, Chiu C, Lin M, et al. Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry. J Proteome Res. 2013;12:3573-85 pubmed publisher |
| Shie M, Ding S. Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements. Biomaterials. 2013;34:6589-606 pubmed publisher |
| Liu T, Zhang S, Xiang D, Wang Y. Induction of hepatocyte-like cells from mouse embryonic stem cells by lentivirus-mediated constitutive expression of Foxa2/Hnf4a. J Cell Biochem. 2013;114:2531-41 pubmed publisher |
| Babic I, Anderson E, Tanaka K, Guo D, Masui K, Li B, et al. EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer. Cell Metab. 2013;17:1000-8 pubmed publisher |
| Formosa R, Xuereb Anastasi A, Vassallo J. Aip regulates cAMP signalling and GH secretion in GH3 cells. Endocr Relat Cancer. 2013;20:495-505 pubmed publisher |
| Das I, Png C, Oancea I, Hasnain S, Lourie R, Proctor M, et al. Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. J Exp Med. 2013;210:1201-16 pubmed publisher |
| Zeng J, Kim D, Li K, Sharp K, Steward O, Zaucke F, et al. Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception. Eur J Pain. 2013;17:1458-64 pubmed publisher |
| Yoon H, Radulovic M, Wu J, Blaber S, Blaber M, Fehlings M, et al. Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity. J Neurochem. 2013;127:283-98 pubmed publisher |
| Rafalski V, Ho P, Brett J, Ucar D, Dugas J, Pollina E, et al. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol. 2013;15:614-24 pubmed publisher |
| Cai H, Peng F. Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells. Oncol Rep. 2013;30:269-75 pubmed publisher |
| Kral R, Mayer C, Vanas V, Gsur A, Sutterlüty Fall H. In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected. Cell Biochem Funct. 2014;32:96-100 pubmed publisher |
| Huang T, Chong K, Ojcius D, Wu Y, Ko Y, Wu C, et al. Hirsutella sinensis mycelium suppresses interleukin-1? and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Sci Rep. 2013;3:1374 pubmed publisher |
| Park Y, Carr T. Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines. Nutr Res. 2013;33:154-61 pubmed publisher |
| Allen J, Bell G, Kuzirian A, Hanlon R. Cuttlefish skin papilla morphology suggests a muscular hydrostatic function for rapid changeability. J Morphol. 2013;274:645-56 pubmed publisher |
| Drucker K, Paulsen A, Giannini C, Decker P, Blaber S, Blaber M, et al. Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma. Neuro Oncol. 2013;15:305-18 pubmed publisher |
| Salih D, Rashid A, Colas D, de la Torre Ubieta L, Zhu R, Morgan A, et al. FoxO6 regulates memory consolidation and synaptic function. Genes Dev. 2012;26:2780-801 pubmed publisher |
| Berryer M, Hamdan F, Klitten L, Møller R, Carmant L, Schwartzentruber J, et al. Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat. 2013;34:385-94 pubmed publisher |
| Xie W, Parker J, Heaps C. Exercise training-enhanced, endothelium-dependent dilation mediated by altered regulation of BK(Ca) channels in collateral-dependent porcine coronary arterioles. Microcirculation. 2013;20:170-82 pubmed publisher |
| Lin C, Jan M, Kuo J, Hsu L, Lin Y. Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death. Eur J Pharm Sci. 2012;47:865-74 pubmed publisher |
| Hånell A, Clausen F, Djupsjö A, Vallstedt A, Patra K, Israelsson C, et al. Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice. J Neurotrauma. 2012;29:2660-71 pubmed publisher |
| Lee W, Kan D, Chen Y, Han S, Lu K, Chien C. Suppression of extensive neurofilament phosphorylation rescues ?-Internexin/peripherin-overexpressing PC12 cells from neuronal cell death. PLoS ONE. 2012;7:e43883 pubmed publisher |
| Aro E, Khatri R, Gerard O Riley R, Mangiavini L, Myllyharju J, Schipani E. Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes. J Biol Chem. 2012;287:37134-44 pubmed publisher |
| Maj M, Milenkovic I, Bauer J, Berggard T, Veit M, Ilhan Mutlu A, et al. Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture. Front Mol Neurosci. 2012;5:84 pubmed publisher |
| Minutolo A, Grelli S, Marino Merlo F, Cordero F, Brandi A, Macchi B, et al. D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent. Cell Death Dis. 2012;3:e358 pubmed publisher |
| CALNAN D, Webb A, White J, Stowe T, Goswami T, Shi X, et al. Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging (Albany NY). 2012;4:462-79 pubmed |
| Wu H, Lu Y, Shen C, Patel N, Gan L, Xiong W, et al. Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation. Neuron. 2012;75:94-107 pubmed publisher |
| Wu M, Hou M, Lin Y, Kuo C. 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes. J Agric Food Chem. 2012;60:7262-9 pubmed publisher |
| Li T, Liu G, Li J, Wang X, Liu Q, Liu Z, et al. Mechanisms of prostate permeability triggered by microbubble-mediated acoustic cavitation. Cell Biochem Biophys. 2012;64:147-53 pubmed publisher |
| Wehenkel M, Ban J, Ho Y, Carmony K, Hong J, Kim K. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer. 2012;107:53-62 pubmed publisher |
| Dawson P, Rakoczy J, Simmons D. Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biol Reprod. 2012;87:43 pubmed publisher |
| Wu H, Lu Y, Barik A, Joseph A, Taketo M, Xiong W, et al. ?-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012;139:2392-404 pubmed publisher |
| Herroon M, Rajagurubandara E, Rudy D, Chalasani A, Hardaway A, Podgorski I. Macrophage cathepsin K promotes prostate tumor progression in bone. Oncogene. 2013;32:1580-93 pubmed publisher |
| Pohjanvirta R, Miettinen H, Sankari S, Hegde N, Lindén J. Unexpected gender difference in sensitivity to the acute toxicity of dioxin in mice. Toxicol Appl Pharmacol. 2012;262:167-76 pubmed publisher |
| Yu M, Ge C, Zeng W, Mi Y, Zhang C. Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-?B signalling cascade. Cell Biol Int. 2012;36:705-12 pubmed publisher |
| Chang W, Hu F, Yu C, Wang H, Feng H, Lan C, et al. Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer. Head Neck. 2013;35:413-9 pubmed publisher |
| Hsieh Y, Chou L, Chang P, Yang C, Kao M, Hong C. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1? (HIF-1?). J Comp Neurol. 2012;520:2903-16 pubmed publisher |
| Carmony K, Kim K. PROTAC-induced proteolytic targeting. Methods Mol Biol. 2012;832:627-38 pubmed publisher |
| Govaert K, Nijkamp M, Emmink B, Steller E, Minchinton A, Kranenburg O, et al. Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation. Br J Surg. 2012;99:567-75 pubmed publisher |
| Zhang B, Liang C, Bates R, Yin Y, Xiong W, Mei L. Wnt proteins regulate acetylcholine receptor clustering in muscle cells. Mol Brain. 2012;5:7 pubmed publisher |
| Zhou Q, Xu G, Zhang X, Cao C, Zhou Z. Proteomics of post-traumatic proliferative vitreoretinopathy in rabbit retina reveals alterations to a variety of functional proteins. Curr Eye Res. 2012;37:318-26 pubmed publisher |
| Swain U, Rao K. Age-dependent decline of DNA base excision repair activity in rat cortical neurons. Mech Ageing Dev. 2012;133:186-94 pubmed publisher |
| Lee W, Chen Y, Kan D, Chien C. A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells. J Biomed Sci. 2012;19:8 pubmed publisher |
| Edgel K, McMillen T, Wei H, Pamir N, Houston B, Caldwell M, et al. Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice. Biochim Biophys Acta. 2012;1821:425-34 pubmed publisher |
| Szabat M, Kalynyak T, Lim G, Chu K, Yang Y, Asadi A, et al. Musashi expression in ?-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes. Cell Death Dis. 2011;2:e232 pubmed publisher |
| Tsai Y, Huang Y, Chao Y, Hu K, Chin L, Chou S, et al. Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis. ACS Nano. 2011;5:9354-69 pubmed publisher |
| Yang L, Yang Z, Guo R, Ye J, Liu H. Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice. J Renin Angiotensin Aldosterone Syst. 2012;13:67-75 pubmed publisher |
| Khan Z, Akhtar M, Ekström T. HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase. Int J Mol Med. 2011;28:977-83 pubmed publisher |
| Chiang K, Yeh C, Chen H, Lee J, Juang H, Chen M, et al. 19-Nor-2?-(3-hydroxypropyl)-1?,25-dihydroxyvitamin D3 (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells. Steroids. 2011;76:1513-9 pubmed publisher |
| Gao L, Coope H, Grant S, Ma A, Ley S, Harhaj E. ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling. J Biol Chem. 2011;286:36592-602 pubmed publisher |
| Patschan O, Shariat S, Chade D, Karakiewicz P, Ashfaq R, Lotan Y, et al. Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder. World J Urol. 2012;30:785-94 pubmed publisher |
| Corcoran M, Lichtenstein A, Meydani M, Dillard A, Schaefer E, Lamon Fava S. The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu. J Mol Endocrinol. 2011;47:109-17 pubmed |
| Ge X, Yin L, Ma H, Li T, Chiang J, Zhang Y. Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis. J Lipid Res. 2011;52:1561-8 pubmed publisher |
| Vitari A, Leong K, Newton K, Yee C, O Rourke K, Liu J, et al. COP1 is a tumour suppressor that causes degradation of ETS transcription factors. Nature. 2011;474:403-6 pubmed publisher |
| Winter N, Nimzyk R, Bösche C, Meyer A, Bullerdiek J. Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2. PLoS ONE. 2011;6:e18837 pubmed publisher |
| Nijkamp M, Hoogwater F, Govaert K, Steller E, Verheem A, Kranenburg O, et al. A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver. J Surg Oncol. 2011;104:198-204 pubmed publisher |
| Huang A, Kao Y, Toh S, Lin P, Chou C, Hu H, et al. UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. Biochem Pharmacol. 2011;82:35-42 pubmed publisher |
| Raats D, de Bruijn M, Steller E, Emmink B, Borel Rinkes I, Kranenburg O. Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737. Cell Oncol (Dordr). 2011;34:307-13 pubmed publisher |
| Scarisbrick I, Epstein B, Cloud B, Yoon H, Wu J, Renner D, et al. Functional role of kallikrein 6 in regulating immune cell survival. PLoS ONE. 2011;6:e18376 pubmed publisher |
| Kim S, Nian C, McIntosh C. Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation. J Lipid Res. 2011;52:759-70 pubmed publisher |
| Hildebrand J, Luo Z, Manske M, Price Troska T, Ziesmer S, Lin W, et al. A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. J Exp Med. 2010;207:2569-79 pubmed publisher |
| Chen C, Chyau C, Liao C, Hu T, Kuo C. Enhanced anti-inflammatory activities of Monascus pilosus fermented products by addition of ginger to the medium. J Agric Food Chem. 2010;58:12006-13 pubmed publisher |
| Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma J. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010;107:17551-6 pubmed publisher |
| Chavez C, Keravala A, Woodard L, Hillman R, Stowe T, Chu J, et al. Kinetics and longevity of ΦC31 integrase in mouse liver and cultured cells. Hum Gene Ther. 2010;21:1287-97 pubmed publisher |
| van Houdt W, de Bruijn M, Emmink B, Raats D, Hoogwater F, Borel Rinkes I, et al. Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition. Cell Oncol. 2010;32:245-57 pubmed publisher |
| de Bruijn M, Raats D, Hoogwater F, van Houdt W, Cameron K, Medema J, et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br J Cancer. 2010;102:1254-64 pubmed publisher |
| Lan C, Sheng J, Fang D, Meng Q, Fan L, Huang Z. Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells. J Dig Dis. 2010;11:43-9 pubmed publisher |
| Matluk N, Rochira J, Karaczyn A, Adams T, Verdi J. A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. BMC Biol. 2010;8:7 pubmed publisher |
| Maj M, Gartner W, Ilhan A, Neziri D, Attems J, Wagner L. Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin. J Endocrinol. 2010;205:25-36 pubmed publisher |
| Macchi B, Minutolo A, Grelli S, Cardona F, Cordero F, Mastino A, et al. The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. Glycobiology. 2010;20:500-6 pubmed publisher |
| Woodard L, Hillman R, Keravala A, Lee S, Calos M. Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity. Gene Ther. 2010;17:217-26 pubmed publisher |
| Zhang B, Luo S, Wang Q, Suzuki T, Xiong W, Mei L. LRP4 serves as a coreceptor of agrin. Neuron. 2008;60:285-97 pubmed publisher |
| Luo S, Zhang B, Dong X, Tao Y, Ting A, Zhou Z, et al. HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance. Neuron. 2008;60:97-110 pubmed publisher |
| Fogarty J, Delp M, Muller Delp J, Laine G, Parker J, Heaps C. Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs. J Vasc Res. 2009;46:152-61 pubmed publisher |
| Barthel S, Gavino J, Wiese G, Jaynes J, Siddiqui J, Dimitroff C. Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin. Glycobiology. 2008;18:806-17 pubmed publisher |
| Elsawa S, Novak A, Grote D, Konopleva M, Andreeff M, Witzig T, et al. CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia. Leuk Res. 2008;32:1895-902 pubmed publisher |
| Heazlewood C, Cook M, Eri R, Price G, Tauro S, Taupin D, et al. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med. 2008;5:e54 pubmed publisher |
| Dror V, Kalynyak T, Bychkivska Y, Frey M, Tee M, Jeffrey K, et al. Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells. J Biol Chem. 2008;283:9909-16 pubmed publisher |
| Alejandro E, Johnson J. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem. 2008;283:2407-17 pubmed |
| Greer E, Oskoui P, Banko M, Maniar J, Gygi M, Gygi S, et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007;282:30107-19 pubmed |
| Zhang S, Suvannasankha A, Crean C, White V, Johnson A, Chen C, et al. OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms. Clin Cancer Res. 2007;13:4750-8 pubmed |
| Ougolkov A, Bone N, Fernandez Zapico M, Kay N, Billadeau D. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood. 2007;110:735-42 pubmed |
| Park K, Hallows J, Chakrabarty P, Davies P, Vincent I. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J Neurosci. 2007;27:2969-78 pubmed |
| Dennis V, Jefferson A, Singh S, Ganapamo F, Philipp M. Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3. Infect Immun. 2006;74:5780-9 pubmed |
| Abramovich D, Parborell F, Tesone M. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biol Reprod. 2006;75:434-41 pubmed |
| Rice P, Peters S, Beard K, Ahnen D. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways. Mol Cancer Ther. 2006;5:746-54 pubmed |
| Csiszar A, Ahmad M, Smith K, Labinskyy N, Gao Q, Kaley G, et al. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006;168:629-38 pubmed |
| Moiseyev G, Chen Y, Takahashi Y, Wu B, Ma J. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A. 2005;102:12413-8 pubmed |
| Barnidge D, Jelinek D, Muddiman D, Kay N. Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents. J Proteome Res. 2005;4:1310-7 pubmed |
| Nagasawa H, Peng Y, Wilson P, Lio Y, Chen D, Bedford J, et al. Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations. Radiat Res. 2005;164:141-7 pubmed |
| Liu X, Manser T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. J Immunol. 2005;174:4505-15 pubmed |
| Peng Y, Woods R, Beamish H, Ye R, Lees Miller S, Lavin M, et al. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM. Cancer Res. 2005;65:1670-7 pubmed |
| Sung S, Yang H, Uryu K, Lee E, Zhao L, Shineman D, et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol. 2004;165:2197-206 pubmed |
| Adler S, Huang H. Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. Am J Physiol Renal Physiol. 2004;287:F907-13 pubmed |
| Chong V, Costain W, Marriott J, Sindwani S, Knauer D, Wang J, et al. Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment. Pharmacogenomics J. 2004;4:379-87 pubmed |
| Mukherjee P, Abate L, Seyfried T. Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res. 2004;10:5622-9 pubmed |
| Laughlin R, McGugan G, Powell R, Welter B, Temesvari L. Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion. Infect Immun. 2004;72:5349-57 pubmed |
| Watters J, Kraja A, Meucci M, Province M, McLeod H. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A. 2004;101:11809-14 pubmed |
| Dietz A, Souan L, Knutson G, Bulur P, Litzow M, Vuk Pavlovic S. Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. Blood. 2004;104:1094-9 pubmed |
| Hawkins B, Fischer L. Inhibition of insulin synthesis by cyproheptadine: effects on translation. Toxicol Sci. 2004;79:258-65 pubmed |
| Thornton M, Kudo D, Rayman P, Horton C, Molto L, Cathcart M, et al. Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas. J Immunol. 2004;172:3480-90 pubmed |
| Sun D, Huang A, Yan E, Wu Z, Yan C, Kaminski P, et al. Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. Am J Physiol Heart Circ Physiol. 2004;286:H2249-56 pubmed |
| Adler S, Huang H, Wolin M, Kaminski P. Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney. J Am Soc Nephrol. 2004;15:52-60 pubmed |
| Liao J, Xu X, Wargovich M. Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis. Biotechniques. 2000;28:216-8 pubmed |
