Rabbit Polyclonal LC3B Antibody [HRP] | Novus Biologicals NB100-2220H product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Rabbit Polyclonal LC3B Antibody [HRP]

catalog :

NB100-2220H

quantity :

0.1 ml

price :

399 USD

clonality :

polyclonal

host :

rabbit

conjugate :

HRP

reactivity :

human, mouse, rat, dog, cow, zebrafish

application :

western blot, immunoprecipitation

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Benhamron S, Pattanayak S, Berger M, Tirosh B. mTOR activation promotes plasma cell differentiation and bypasses XBP-1 for immunoglobulin secretion. Mol Cell Biol. 2015;35:153-66 pubmed publisher
western blot; human	Song Y, Zhang S, Guo X, Sun K, Han Z, Li R, et al. Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment. Cancer Lett. 2013;339:70-81 pubmed publisher
western blot; human	Guo X, Li D, Hu F, Song J, Zhang S, Deng W, et al. Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells. Cancer Lett. 2012;320:171-9 pubmed publisher
western blot; human	Song J, Qu Z, Guo X, Zhao Q, Zhao X, Gao L, et al. Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells. Autophagy. 2009;5:1131-44 pubmed

product information

Catalog Number :

NB100-2220H

Product Name :

Rabbit Polyclonal LC3B Antibody [HRP]

List Price :

399 USD

product type :

Primary Antibodies

Package Size :

0.1 ml

AltNames :

ATG8F, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, LC3B, lc3b autophagy marker, lc3-i, ii, MAP1 light chain 3-like protein 2, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, map1lc3b, microtubule associated protein 3 b, microtubule associated protein 3 beta, microtubule-associated protein 1 light chain 3 betaMAP1A/MAP1B light chain 3 B, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3B

Buffer :

PBS

Clonality :

Polyclonal

Conjugate :

HRP

Application Summary :

Immunoprecipitation, Western Blot

Host :

Rabbit

Immunogen :

A synthetic peptide made to an N-terminal portion of the human LC3 protein sequence (between residues 1-100). [UniProt# Q9GZQ8]

Localization :

LC3-I is cytoplasmic. LC3-II binds to the autophagic membranes.

Marker :

Autophagosome Marker

Preservative :

No Preservative

Purity :

Immunogen affinity purified

CrossReactivity :

Bacteria, Bovine, Canine, Golden Syrian Hamster, Human, Mouse, Porcine, Primate, Rat, Zebrafish

Storage :

Store at 4C in the dark.

Swissprot Human :

Q9GZQ8

Uses :

This LC3 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry-paraffin embedded sections, Immunoprecipitation and Western Blot. Use in Immunohistochemistry-Frozen sections reported in scientific literature (PMID: 20008275) In Western blot bands are seen ~17 and 19 kDa corresponding to LC3-II and LC3-I. In some cases a non-specific band is seen at ~21 kDa in mouse protein. In ICC/IF, cytoplasmic staining was observed in HeLa cells.