Reference |
---|
Tajima O, Fujita Y, Ohmi Y, Furukawa K, Furukawa K. Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway. PLoS ONE. 2023;18:e0281414 pubmed publisher
|
Yang W, Yang M, Tian Y, Jiang Q, Loor J, Cao J, et al. Effect of Myricetin on Lipid Metabolism in Primary Calf Hepatocytes Challenged with Long-Chain Fatty Acids. Metabolites. 2022;12: pubmed publisher
|
McKernan C, Khatri A, Hannigan M, Child J, Chen Q, Mayro B, et al. ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain. Cell Rep. 2022;40:111268 pubmed publisher
|
Xiang J, Deng Y, Liu H, Pu Y. LncRNA MALAT1 Promotes PPARα/CD36-Mediated Hepatic Lipogenesis in Nonalcoholic Fatty Liver Disease by Modulating miR-206/ARNT Axis. Front Bioeng Biotechnol. 2022;10:858558 pubmed publisher
|
Yang W, Wang S, Loor J, Jiang Q, Gao C, Yang M, et al. Role of sortilin 1 (SORT1) on lipid metabolism in bovine liver. J Dairy Sci. 2022;105:5420-5434 pubmed publisher
|
Wang C, MacIntyre B, Mutch D. Inhibition of Δ-6 desaturase reduces fatty acid re-esterification in 3T3-L1 adipocytes independent of changes in n3-PUFA cellular content. Biochim Biophys Acta Mol Cell Biol Lipids. 2022;1867:159160 pubmed publisher
|
Yang W, Wang S, Loor J, Lopes M, Zhao Y, Ma X, et al. Role of diacylglycerol O-acyltransferase (DGAT) isoforms in bovine hepatic fatty acid metabolism. J Dairy Sci. 2022;105:3588-3600 pubmed publisher
|
Xu X, Sun S, Liang L, Lou C, He Q, Ran M, et al. Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice. Front Nutr. 2021;8:756565 pubmed publisher
|
Sozen E, Demirel Yalciner T, Sari D, Avcilar C, Samanci T, Ozer N. Deficiency of SREBP1c modulates autophagy mediated lipid droplet catabolism during oleic acid induced steatosis. Metabol Open. 2021;12:100138 pubmed publisher
|
Mikolajczak A, Sallam N, Singh R, Scheidl T, Walsh E, Larion S, et al. Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction. Am J Physiol Endocrinol Metab. 2021;321:E581-E591 pubmed publisher
|
Shao F, Bian X, Wang J, Xu D, Guo W, Jiang H, et al. Prognostic Impact of PCK1 Protein Kinase Activity-Dependent Nuclear SREBP1 Activation in Non-Small-Cell Lung Carcinoma. Front Oncol. 2021;11:561247 pubmed publisher
|
An S, Lee E, Jeong S, Hong Y, Ahn S, Yang Y. Perinatal exposure to di-(2-ethylhexyl) phthalate induces hepatic lipid accumulation mediated by diacylglycerol acyltransferase 1. Hum Exp Toxicol. 2021;:9603271211003314 pubmed publisher
|
Ali I, Li C, Li L, Kuang M, Shafiq M, Wang Y, et al. Effect of acetate, β-hydroxybutyrate and their interaction on lipogenic gene expression, triglyceride contents and lipid droplet formation in dairy cow mammary epithelial cells. In Vitro Cell Dev Biol Anim. 2021;57:66-75 pubmed publisher
|
Shao F, Bian X, Jiang H, Zhao G, Zhu L, Xu D, et al. Association of phosphoenolpyruvate carboxykinase 1 protein kinase activity-dependent sterol regulatory element-binding protein 1 activation with prognosis of oesophageal carcinoma. Eur J Cancer. 2021;142:123-131 pubmed publisher
|
Ménard C, Wilson A, Dejda A, Miloudi K, Binet F, Crespo Garcia S, et al. miR-106b suppresses pathological retinal angiogenesis. Aging (Albany NY). 2020;12:24836-24852 pubmed publisher
|
Capaci V, Bascetta L, Fantuz M, Beznoussenko G, Sommaggio R, Cancila V, et al. Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome. Nat Commun. 2020;11:3945 pubmed publisher
|
Wang K, Chen Y, Zhang D, Wang R, Zhao Z, Feng M, et al. Effects of 25-hydroxycholecalciferol supplementation in maternal diets on reproductive performance and the expression of genes that regulate lactation in sows. Anim Sci J. 2020;91:e13391 pubmed publisher
|
Cai T, Ke Q, Fang Y, Wen P, Chen H, Yuan Q, et al. Sodium-glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice. Cell Death Dis. 2020;11:390 pubmed publisher
|
Xu D, Wang Z, Xia Y, Shao F, Xia W, Wei Y, et al. The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis. Nature. 2020;580:530-535 pubmed publisher
|
Mesquita I, Ferreira C, Moreira D, Kluck G, Barbosa A, Torrado E, et al. The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. Cell Rep. 2020;30:4052-4064.e7 pubmed publisher
|
Zhang B, Li M, Yang W, Loor J, Wang S, Zhao Y, et al. Orai calcium release-activated calcium modulator 1 (ORAI1) plays a role in endoplasmic reticulum stress in bovine mammary epithelial cells challenged with physiological levels of ketone bodies. J Dairy Sci. 2020;103:4691-4701 pubmed publisher
|
Ganesan D, Ramaian Santhaseela A, Rajasekaran S, Selvam S, Jayavelu T. Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain. J Neurochem. 2020;: pubmed publisher
|
Su K, Dai S, Tang Z, Xu M, Dai C. Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase. Mol Cell. 2019;76:546-561.e8 pubmed publisher
|
Lin R, Wu D, Wu F, Meng Y, Zhang J, Wang X, et al. Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats. Front Endocrinol (Lausanne). 2019;10:620 pubmed publisher
|
Tan J, Huang C, Luo Q, Liu W, Cheng D, Li Y, et al. Soy Isoflavones Ameliorate Fatty Acid Metabolism of Visceral Adipose Tissue by Increasing the AMPK Activity in Male Rats with Diet-Induced Obesity (DIO). Molecules. 2019;24: pubmed publisher
|
Imanishi T, Akeda K, Murata K, Sudo A. Effect of diminished flow in rabbit lumbar arteries on intervertebral disc matrix changes using MRI T2-mapping and histology. BMC Musculoskelet Disord. 2019;20:347 pubmed publisher
|
Dong J, Loor J, Zuo R, Chen X, Liang Y, Wang Y, et al. Low abundance of mitofusin 2 in dairy cows with moderate fatty liver is associated with alterations in hepatic lipid metabolism. J Dairy Sci. 2019;: pubmed publisher
|
Zhu Y, Guan Y, Loor J, Sha X, Coleman D, Zhang C, et al. Fatty acid-induced endoplasmic reticulum stress promoted lipid accumulation in calf hepatocytes, and endoplasmic reticulum stress existed in the liver of severe fatty liver cows. J Dairy Sci. 2019;: pubmed publisher
|
Lee S, Lee K, Kim M, Song Y, Goo J, Park C. Serial Texture Analyses on ADC Maps for Evaluation of Antiangiogenic Therapy in Rat Breast Cancer. Anticancer Res. 2019;39:1875-1882 pubmed publisher
|
Kalainayakan S, Ghosh P, Dey S, FitzGerald K, Sohoni S, Konduri P, et al. Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression. Sci Rep. 2019;9:1405 pubmed publisher
|
Timpano S, Guild B, Specker E, Melanson G, Medeiros P, Sproul S, et al. Physioxic human cell culture improves viability, metabolism, and mitochondrial morphology while reducing DNA damage. FASEB J. 2019;33:5716-5728 pubmed publisher
|
Zhu Y, Liu G, Du X, Shi Z, Jin M, Sha X, et al. Expression patterns of hepatic genes involved in lipid metabolism in cows with subclinical or clinical ketosis. J Dairy Sci. 2019;102:1725-1735 pubmed publisher
|
Jia H, Li X, Liu G, Loor J, Bucktrout R, Sun X, et al. Perilipin 5 promotes hepatic steatosis in dairy cows through increasing lipid synthesis and decreasing very low density lipoprotein assembly. J Dairy Sci. 2019;102:833-845 pubmed publisher
|
Megele R, Riemenschneider M, Dodoo Schittko F, Feyrer M, Kleindienst A. Intra-tumoral treatment with oxygen-ozone in glioblastoma: A systematic literature search and results of a case series. Oncol Lett. 2018;16:5813-5822 pubmed publisher
|
Du X, Shen T, Wang H, Qin X, Xing D, Ye Q, et al. Adaptations of hepatic lipid metabolism and mitochondria in dairy cows with mild fatty liver. J Dairy Sci. 2018;101:9544-9558 pubmed publisher
|
Zhang D, Wu M, Cai Z, Liao N, Ke K, Liu H, et al. Chemotherapeutic Drug Based Metal-Organic Particles for Microvesicle-Mediated Deep Penetration and Programmable pH/NIR/Hypoxia Activated Cancer Photochemotherapy. Adv Sci (Weinh). 2018;5:1700648 pubmed publisher
|
Li L, He M, Xiao H, Liu X, Wang K, Zhang Y. Acetic Acid Influences BRL-3A Cell Lipid Metabolism via the AMPK Signalling Pathway. Cell Physiol Biochem. 2018;45:2021-2030 pubmed publisher
|
Donepudi A, Ferrell J, Boehme S, Choi H, Chiang J. Deficiency of cholesterol 7α-hydroxylase in bile acid synthesis exacerbates alcohol-induced liver injury in mice. Hepatol Commun. 2018;2:99-112 pubmed publisher
|
Chen C, Cheng T, Ho C, Wang J, Weng S, Hou Y, et al. Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study. Oncotarget. 2017;8:108989-108999 pubmed publisher
|
Du X, Yang Y, Xu C, Peng Z, Zhang M, Lei L, et al. Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis. Oncotarget. 2017;8:91362-91378 pubmed publisher
|
Yang T, Yao H, Chiang M. Red algae (Gelidium amansii) hot-water extract ameliorates lipid metabolism in hamsters fed a high-fat diet. J Food Drug Anal. 2017;25:931-938 pubmed publisher
|
Puchert M, Pelkner F, Stein G, Angelov D, Boltze J, Wagner D, et al. Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS. Mol Cell Neurosci. 2017;85:105-118 pubmed publisher
|
Wang L, Zheng Q, Yuan Y, Li Y, Gong X. Effects of 17β-estradiol and 2-methoxyestradiol on the oxidative stress-hypoxia inducible factor-1 pathway in hypoxic pulmonary hypertensive rats. Exp Ther Med. 2017;13:2537-2543 pubmed publisher
|
Kachaylo E, Tschuor C, Calo N, Borgeaud N, Ungethüm U, Limani P, et al. PTEN Down-Regulation Promotes β-Oxidation to Fuel Hypertrophic Liver Growth After Hepatectomy in Mice. Hepatology. 2017;66:908-921 pubmed publisher
|
Tong D, Liu Q, Liu G, Yuan W, Wang L, Guo Y, et al. The HIF/PHF8/AR axis promotes prostate cancer progression. Oncogenesis. 2016;5:e283 pubmed publisher
|
Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
|
Timpano S, Uniacke J. Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation. J Biol Chem. 2016;291:10772-82 pubmed publisher
|
Fujimoto Y, Urashima T, Shimura D, Ito R, Kawachi S, Kajimura I, et al. Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats. PLoS ONE. 2016;11:e0148666 pubmed publisher
|
Kim J, Lee H, Goo J, Kim M, Chung D. Correlation of volumetric perfusion CT parameters with hypoxia inducible factor-1 alpha expression in a rabbit VX2 tumor model. Acta Radiol. 2016;57:708-15 pubmed publisher
|
Ohmoto T, Yoshitani N, Nishitsuji K, Takayama T, Yanagisawa Y, Takeya M, et al. CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: molecular analysis of aggressive invasion and metastasis. Pathol Int. 2015;65:264-70 pubmed publisher
|
Hénique C, Mansouri A, Vavrova E, Lenoir V, Ferry A, Esnous C, et al. Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype. FASEB J. 2015;29:2473-83 pubmed publisher
|
Deng Q, Liu G, Liu L, Zhang Y, Yin L, Shi X, et al. BHBA influences bovine hepatic lipid metabolism via AMPK signaling pathway. J Cell Biochem. 2015;116:1070-9 pubmed publisher
|
Bruns D, Brown R, Stenmark K, Buttrick P, Walker L. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015;308:L158-67 pubmed publisher
|
Su E, Xin H, Yin P, Dyson M, Coon J, Farrow K, et al. Impaired fetoplacental angiogenesis in growth-restricted fetuses with abnormal umbilical artery doppler velocimetry is mediated by aryl hydrocarbon receptor nuclear translocator (ARNT). J Clin Endocrinol Metab. 2015;100:E30-40 pubmed publisher
|
Niemi H, Honkonen K, Korpisalo P, Huusko J, Kansanen E, Merentie M, et al. HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery. Eur J Clin Invest. 2014;44:989-99 pubmed publisher
|
Motzer R, Hutson T, Hudes G, Figlin R, Martini J, English P, et al. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother Pharmacol. 2014;74:739-50 pubmed publisher
|
Xiao W, Shinohara M, Komori K, Sakai Y, Matsui H, Osada T. The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes. Biotechnol Prog. 2014;30:1401-10 pubmed publisher
|
Ramamoorthy P, Shi H. Ischemia induces different levels of hypoxia inducible factor-1? protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun. 2014;2:51 pubmed publisher
|
Obama T, Takayanagi T, Kobayashi T, Bourne A, Elliott K, Charbonneau M, et al. Vascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1?. Am J Hypertens. 2015;28:10-4 pubmed publisher
|
Sun W, Depping R, Jelkmann W. Interleukin-1? promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production. Cell Death Dis. 2014;5:e1020 pubmed publisher
|
Kaira K, Murakami H, Endo M, Ohde Y, Naito T, Kondo H, et al. Biological correlation of ¹?F-FDG uptake on PET in pulmonary neuroendocrine tumors. Anticancer Res. 2013;33:4219-28 pubmed
|
Chaux A, Albadine R, Schultz L, Hicks J, Carducci M, Argani P, et al. Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas. Hum Pathol. 2013;44:2323-30 pubmed publisher
|
Sceneay J, Liu M, Chen A, Wong C, Bowtell D, Möller A. The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo. PLoS ONE. 2013;8:e66388 pubmed publisher
|
Li C, Hashimi S, Cao S, Mellick A, Duan W, Good D, et al. The mechanisms of chansu in inducing efficient apoptosis in colon cancer cells. Evid Based Complement Alternat Med. 2013;2013:849054 pubmed publisher
|
Li J, Levick S, Dipette D, Janicki J, Supowit S. Alpha-calcitonin gene-related peptide is protective against pressure overload-induced heart failure. Regul Pept. 2013;185:20-8 pubmed publisher
|
Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB J. 2013;27:4059-75 pubmed publisher
|
Yang C, Lee H, Pal S, Jove V, Deng J, Zhang W, et al. B cells promote tumor progression via STAT3 regulated-angiogenesis. PLoS ONE. 2013;8:e64159 pubmed publisher
|
Toba H, Kondo K, Sadohara Y, Otsuka H, Morimoto M, Kajiura K, et al. 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1?, glucose transporter-1 and vascular endothelial growth factor in thymic e. Eur J Cardiothorac Surg. 2013;44:e105-12 pubmed publisher
|
Kar A, Macgibeny M, Gervasi N, Gioio A, Kaplan B. Intra-axonal synthesis of eukaryotic translation initiation factors regulates local protein synthesis and axon growth in rat sympathetic neurons. J Neurosci. 2013;33:7165-74 pubmed publisher
|
Lundgrin E, Park M, Sharp J, Tang W, Thomas J, Asosingh K, et al. Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year. Ann Am Thorac Soc. 2013;10:1-9 pubmed publisher
|
Aziz S, Sznol J, Adeniran A, Parisi F, Kluger Y, Camp R, et al. Expression of drug targets in primary and matched metastatic renal cell carcinoma tumors. BMC Clin Pathol. 2013;13:3 pubmed publisher
|
Reddy V, Padmavathi P, Kavitha G, Saradamma B, Varadacharyulu N. Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties. Mol Cell Biochem. 2013;375:39-47 pubmed publisher
|
Brenner R, Slayden O. Molecular and functional aspects of menstruation in the macaque. Rev Endocr Metab Disord. 2012;13:309-18 pubmed publisher
|
Ioannou M, Pyrpasopoulou A, Simos G, Paraskeva E, Nikolaidou C, Venizelos I, et al. Upregulation of VEGF expression is associated with accumulation of HIF-1? in the skin of naïve scleroderma patients. Mod Rheumatol. 2013;23:1245-8 pubmed publisher
|
Tirziu D, Jaba I, Yu P, Larrivee B, Coon B, Cristofaro B, et al. Endothelial nuclear factor-?B-dependent regulation of arteriogenesis and branching. Circulation. 2012;126:2589-600 pubmed publisher
|
Shinmei S, Sakamoto N, Goto K, Sentani K, Anami K, Hayashi T, et al. MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma. Int J Urol. 2013;20:468-77 pubmed publisher
|
Salem A, Howell A, Sartini M, Sotgia F, Lisanti M. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1?, autophagy and ketone body production. Cell Cycle. 2012;11:4167-73 pubmed publisher
|
Clarke D, Al Ahmad A, Lee B, Parham C, Auckland L, Fertala A, et al. Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin ?5?1 and ERK-dependent signaling pathways. PLoS ONE. 2012;7:e45257 pubmed publisher
|
Ding A, Kalaignanasundaram P, Ricardo S, Abdelkader A, Witting P, Broughton B, et al. Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease. Clin Exp Pharmacol Physiol. 2012;39:917-29 pubmed publisher
|
Gu H, Zheng X, Abu Seman N, Gu T, Botusan I, Sunkari V, et al. Impact of the hypoxia-inducible factor-1 ? (HIF1A) Pro582Ser polymorphism on diabetes nephropathy. Diabetes Care. 2013;36:415-21 pubmed publisher
|
Zhao Y, Xiong X, Jia L, Sun Y. Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death Dis. 2012;3:e386 pubmed publisher
|
Mhawech Fauceglia P, Wang D, Samrao D, Menesses T, Godoy H, Ough F, et al. The role of hypoxic-inducible factor (HIF1?) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients. BMJ Open. 2012;2: pubmed publisher
|
Chiavarina B, Martinez Outschoorn U, Whitaker Menezes D, Howell A, Tanowitz H, Pestell R, et al. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1? and HIF2? in tumor-associated fibroblasts and human breast cancer cells. Cell Cycle. 2012;11:3280-9 pubmed publisher
|
Mayer A, Schneider F, Vaupel P, Sommer C, Schmidberger H. Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma. Int J Oncol. 2012;41:1260-70 pubmed publisher
|
Kishimoto K, Yoshida S, Ibaragi S, Yoshioka N, Okui T, Hu G, et al. Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer. Oral Oncol. 2012;48:1120-7 pubmed publisher
|
Jiang W, Zhu Z, McGinley J, El Bayoumy K, Manni A, Thompson H. Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. Cancer Res. 2012;72:3795-806 pubmed publisher
|
Galzio R, Cristiano L, Fidoamore A, Cifone M, Benedetti E, Cinque B, et al. Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy. J Cell Biochem. 2012;113:3342-52 pubmed publisher
|
Weber D, Tille J, Combescure C, Egger J, Laouiti M, Hammad K, et al. The prognostic value of expression of HIF1?, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy. Radiat Oncol. 2012;7:66 pubmed publisher
|
Chaux A, Schultz L, Albadine R, Hicks J, Kim J, Allaf M, et al. Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas. Hum Pathol. 2012;43:2129-37 pubmed publisher
|
Jeong C, Yoon C, Jeong S, Hong S, Byun S, Kwak C, et al. The role of hypoxia-inducible factor-1? and -2? in androgen insensitive prostate cancer cells. Urol Oncol. 2013;31:1448-56 pubmed publisher
|
Kaira K, Serizawa M, Koh Y, Takahashi T, Hanaoka H, Oriuchi N, et al. Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma. Eur J Cancer. 2012;48:1244-54 pubmed publisher
|
Hölscher M, Schafer K, Krull S, Farhat K, Hesse A, Silter M, et al. Unfavourable consequences of chronic cardiac HIF-1α stabilization. Cardiovasc Res. 2012;94:77-86 pubmed publisher
|
Kaira K, Oriuchi N, Takahashi T, Nakagawa K, Ohde Y, Okumura T, et al. L-type amino acid transporter 1 (LAT1) expression in malignant pleural mesothelioma. Anticancer Res. 2011;31:4075-82 pubmed
|
Chu W, Wan L, Zhao D, Qu X, Cai F, Huo R, et al. Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1?-mediated TRPC signalling. J Cell Mol Med. 2012;16:2022-34 pubmed publisher
|
Kaira K, Nakagawa K, Ohde Y, Okumura T, Takahashi T, Murakami H, et al. Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer. Int J Surg Pathol. 2012;20:223-32 pubmed publisher
|
Kaira K, Abe M, Nakagawa K, Ohde Y, Okumura T, Takahashi T, et al. 18F-FDG uptake on PET in primary mediastinal non-thymic neoplasm: a clinicopathological study. Eur J Radiol. 2012;81:2423-9 pubmed publisher
|
Kaira K, Oriuchi N, Takahashi T, Nakagawa K, Ohde Y, Okumura T, et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Transl Res. 2011;3:468-78 pubmed
|
Kaira K, Okumura T, Nakagawa K, Ohde Y, Takahashi T, Murakami H, et al. MUC1 expression in pulmonary metastatic tumors: a comparison of primary lung cancer. Pathol Oncol Res. 2012;18:439-47 pubmed publisher
|
Kaira K, Ohde Y, Nakagawa K, Okumura T, Murakami H, Takahashi T, et al. Thymidylate synthase expression is closely associated with outcome in patients with pulmonary adenocarcinoma. Med Oncol. 2012;29:1663-72 pubmed publisher
|
Sreekumar P, Hinton D, Kannan R. Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World J Biol Chem. 2011;2:184-92 pubmed publisher
|
Schultz L, Chaux A, Albadine R, Hicks J, Kim J, De Marzo A, et al. Immunoexpression status and prognostic value of mTOR and hypoxia-induced pathway members in primary and metastatic clear cell renal cell carcinomas. Am J Surg Pathol. 2011;35:1549-56 pubmed publisher
|
Peurala E, Koivunen P, Bloigu R, Haapasaari K, Jukkola Vuorinen A. Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients. Breast Cancer Res Treat. 2012;133:179-88 pubmed publisher
|
Schneider C, Krischke G, Rascher W, Gassmann M, Trollmann R. Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation. Brain Dev. 2012;34:261-73 pubmed publisher
|
Kaira K, Ohde Y, Endo M, Nakagawa K, Okumura T, Takahashi T, et al. Expression of 4F2hc (CD98) in pulmonary neuroendocrine tumors. Oncol Rep. 2011;26:931-7 pubmed publisher
|
Monzon F, Alvarez K, Peterson L, Truong L, Amato R, Hernandez McClain J, et al. Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis. Mod Pathol. 2011;24:1470-9 pubmed publisher
|
Evenou F, Hamon M, Fujii T, Takeuchi S, Sakai Y. Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues. Biotechnol Prog. 2011;27:1146-53 pubmed publisher
|
Namas R, Metukuri M, Dhupar R, Velosa C, Jefferson B, Myer E, et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1? in mouse hepatocytes. Shock. 2011;36:196-202 pubmed publisher
|
Park H, Baek K, Lee H, Kwon A, Hwang H, Qadir A, et al. Hypoxia inducible factor-1? directly induces the expression of receptor activator of nuclear factor-?B ligand in periodontal ligament fibroblasts. Mol Cells. 2011;31:573-8 pubmed publisher
|
Weroha S, Oberg A, Ziegler K, Dakhilm S, Rowland K, Hartmann L, et al. Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma. Gynecol Oncol. 2011;122:116-20 pubmed publisher
|
Kaira K, Okumura T, Ohde Y, Takahashi T, Murakami H, Oriuchi N, et al. Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors. J Nucl Med. 2011;52:705-11 pubmed publisher
|
Huang L, Chuang I, Dong H, Yang R. Hypoxia-inducible factor 1? regulates the expression of the mitochondrial ATPase inhibitor protein (IF1) in rat liver. Shock. 2011;36:90-6 pubmed publisher
|
Hölscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, et al. Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J Biol Chem. 2011;286:11185-94 pubmed publisher
|
Gibbings S, Elkins N, Fitzgerald H, Tiao J, Weyman M, Shibao G, et al. Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}. J Biol Chem. 2011;286:961-75 pubmed publisher
|
Chiavarina B, Whitaker Menezes D, Migneco G, Martinez Outschoorn U, Pavlides S, Howell A, et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle. 2010;9:3534-51 pubmed
|
Martinez Outschoorn U, Trimmer C, Lin Z, Whitaker Menezes D, Chiavarina B, Zhou J, et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment. Cell Cycle. 2010;9:3515-33 pubmed
|
Tickoo S, Milowsky M, Dhar N, Dudas M, Gallagher D, Al Ahmadie H, et al. Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications. BJU Int. 2011;107:844-849 pubmed publisher
|
Monsef N, Soller M, Panagopoulos I, Abrahamsson P. HIF1alpha isoforms in benign and malignant prostate tissue and their correlation to neuroendocrine differentiation. BMC Cancer. 2010;10:385 pubmed publisher
|
Kaira K, Endo M, Abe M, Nakagawa K, Ohde Y, Okumura T, et al. Biologic correlates of ¹?F-FDG uptake on PET in pulmonary pleomorphic carcinoma. Lung Cancer. 2011;71:144-50 pubmed publisher
|
Kaira K, Endo M, Abe M, Nakagawa K, Ohde Y, Okumura T, et al. Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors. J Clin Oncol. 2010;28:3746-53 pubmed publisher
|
Ioannou M, Mylonis I, Kouvaras E, Papamichali R, Daponte A, Paraskeva E, et al. Validated analysis of HIF-1alpha expression in cancer cells using a controlled and comparative immunoassay. Oncol Rep. 2010;24:161-9 pubmed
|
Choudhury K, Yagle K, Swanson P, Krohn K, Rajendran J. A robust automated measure of average antibody staining in immunohistochemistry images. J Histochem Cytochem. 2010;58:95-107 pubmed publisher
|
Lee D, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal M, et al. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. J Biol Chem. 2009;284:29065-76 pubmed publisher
|
Evenou F, Fujii T, Sakai Y. Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane. Tissue Eng Part C Methods. 2010;16:311-8 pubmed publisher
|
Aubert S, Fauquette V, Hemon B, Lepoivre R, Briez N, Bernard D, et al. MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression. Cancer Res. 2009;69:5707-15 pubmed publisher
|
Rhoads R, Johnson R, Rathbone C, Liu X, Temm Grove C, Sheehan S, et al. Satellite cell-mediated angiogenesis in vitro coincides with a functional hypoxia-inducible factor pathway. Am J Physiol Cell Physiol. 2009;296:C1321-8 pubmed publisher
|
Gossl M, Versari D, Lerman L, Chade A, Beighley P, Erbel R, et al. Low vasa vasorum densities correlate with inflammation and subintimal thickening: potential role in location--determination of atherogenesis. Atherosclerosis. 2009;206:362-8 pubmed publisher
|
Hatipoglu O, Hirohata S, Cilek M, Ogawa H, Miyoshi T, Obika M, et al. ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells. J Biol Chem. 2009;284:16325-33 pubmed publisher
|
Virmani S, Rhee T, Ryu R, Sato K, Lewandowski R, Mulcahy M, et al. Comparison of hypoxia-inducible factor-1alpha expression before and after transcatheter arterial embolization in rabbit VX2 liver tumors. J Vasc Interv Radiol. 2008;19:1483-9 pubmed publisher
|
Stagg J, Sharkey J, Pommey S, Young R, Takeda K, Yagita H, et al. Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response. Proc Natl Acad Sci U S A. 2008;105:16254-9 pubmed publisher
|
Flynn J, Wang L, Gillespie D, Stoddard G, Reid J, Owens J, et al. Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme. Cancer. 2008;113:1032-42 pubmed publisher
|
Rosenberger C, Rosen S, Shina A, Frei U, Eckardt K, Flippin L, et al. Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney. Nephrol Dial Transplant. 2008;23:3472-8 pubmed publisher
|
Radek K, Kovacs E, Gallo R, DiPietro L. Acute ethanol exposure disrupts VEGF receptor cell signaling in endothelial cells. Am J Physiol Heart Circ Physiol. 2008;295:H174-84 pubmed publisher
|
Diensthuber M, Potinius M, Rodt T, Stan A, Welkoborsky H, Samii M, et al. Expression of bcl-2 is associated with microvessel density in olfactory neuroblastoma. J Neurooncol. 2008;89:131-9 pubmed publisher
|
López Avilés S, Lambea E, Moldón A, Grande M, Fajardo A, Rodríguez Gabriel M, et al. Activation of Srk1 by the mitogen-activated protein kinase Sty1/Spc1 precedes its dissociation from the kinase and signals its degradation. Mol Biol Cell. 2008;19:1670-9 pubmed publisher
|
Klatte T, Seligson D, Riggs S, Leppert J, Berkman M, Kleid M, et al. Hypoxia-inducible factor 1 alpha in clear cell renal cell carcinoma. Clin Cancer Res. 2007;13:7388-93 pubmed
|
Cabuk D, Basaran G, Celikel C, Dane F, Yumuk P, Iyikesici M, et al. Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival. Oncology. 2007;72:111-7 pubmed
|
Yamamoto Y, Ibusuki M, Okumura Y, Kawasoe T, Kai K, Iyama K, et al. Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer. Breast Cancer Res Treat. 2008;110:465-75 pubmed
|
Tracy K, Dibling B, Spike B, Knabb J, Schumacker P, Macleod K. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol. 2007;27:6229-42 pubmed
|
Monsef N, Helczynski L, Lundwall A, Påhlman S. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate. 2007;67:1219-29 pubmed
|
Anderson K, Tsui P, Guinan P, Rubenstein M. The proliferative response of hela cells to 2-deoxy-D-glucose under hypoxic or anoxic conditions: an analogue for studying some properties of in vivo solid cancers. Anticancer Res. 2006;26:4155-62 pubmed
|
Gagnon P, Simmons D, Bao J, Lei D, Ortmann A, Ohlemiller K. Temporal and genetic influences on protection against noise-induced hearing loss by hypoxic preconditioning in mice. Hear Res. 2007;226:79-91 pubmed
|
Ramanathan M, Pinhal Enfield G, Hao I, Leibovich S. Synergistic up-regulation of vascular endothelial growth factor (VEGF) expression in macrophages by adenosine A2A receptor agonists and endotoxin involves transcriptional regulation via the hypoxia response element in the VEGF promoter. Mol Biol Cell. 2007;18:14-23 pubmed
|
Khan Z, Michalopoulos G, Stolz D. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am J Pathol. 2006;169:1251-69 pubmed
|
Isaacs J, Pili R, Qian D, Dalrymple S, Garrison J, Kyprianou N, et al. Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. Prostate. 2006;66:1768-78 pubmed
|
An H, Maeng O, Kang K, Lee J, Kim Y, Paik S, et al. Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J Biol Chem. 2006;281:33939-48 pubmed
|
Laderoute K, Amin K, Calaoagan J, Knapp M, Le T, Orduna J, et al. 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol Cell Biol. 2006;26:5336-47 pubmed
|
Zheng X, Ruas J, Cao R, Salomons F, Cao Y, Poellinger L, et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol Cell Biol. 2006;26:4628-41 pubmed
|
Kim C, Vocke C, Torres Cabala C, Yang Y, Schmidt L, Walther M, et al. Expression of hypoxia inducible factor-1alpha and 2alpha in genetically distinct early renal cortical tumors. J Urol. 2006;175:1908-14 pubmed
|
Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung A, et al. Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia. Cancer Res. 2006;66:3639-48 pubmed
|
Michelsen J, Thiesson H, Walter S, Ottosen P, Skøtt O, Jensen B. Tissue expression and plasma levels of adrenomedullin in renal cancer patients. Clin Sci (Lond). 2006;111:61-70 pubmed
|
Lu H, Dalgard C, Mohyeldin A, McFate T, Tait A, Verma A. Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J Biol Chem. 2005;280:41928-39 pubmed
|
Murphy B, Sato B, Dalton T, Laderoute K. The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress. Biochem Biophys Res Commun. 2005;337:860-7 pubmed
|
Isaacs J, Jung Y, Mole D, Lee S, Torres Cabala C, Chung Y, et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell. 2005;8:143-53 pubmed
|
Gross J, Fuchs J, Machulik A, Jahnke V, Kietzmann T, Bockmühl U. Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures. Int J Oncol. 2005;27:807-14 pubmed
|
Brown N, Streeter E, Jones A, Harris A, Bicknell R. Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma. Br J Cancer. 2005;92:1696-701 pubmed
|
Li Y, Zhou B, Deng J, Pan Y, Hay N, Hung M. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res. 2005;65:3257-63 pubmed
|
Luyendyk J, Maddox J, Green C, Ganey P, Roth R. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. Hepatology. 2004;40:1342-51 pubmed
|
Caron A, Desrosiers R, Beliveau R. Kidney ischemia-reperfusion regulates expression and distribution of tubulin subunits, beta-actin and rho GTPases in proximal tubules. Arch Biochem Biophys. 2004;431:31-46 pubmed
|
TEZEL G, Wax M. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch Ophthalmol. 2004;122:1348-56 pubmed
|
Cangul H. Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. BMC Genet. 2004;5:27 pubmed
|
Nordal R, Nagy A, Pintilie M, Wong C. Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin Cancer Res. 2004;10:3342-53 pubmed
|
Reichner J, Albina J. Determination of the role of hypoxia-inducible factor 1 in wound healing. Methods Enzymol. 2004;381:527-38 pubmed
|
Bernaudin M, Sharp F. Methods to detect hypoxia-induced ischemic tolerance in the brain. Methods Enzymol. 2004;381:399-416 pubmed
|
Uchida T, Rossignol F, Matthay M, Mounier R, Couette S, Clottes E, et al. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem. 2004;279:14871-8 pubmed
|
de Candia P, Solit D, Giri D, Brogi E, Siegel P, Olshen A, et al. Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors. Proc Natl Acad Sci U S A. 2003;100:12337-42 pubmed
|
Burke B, Giannoudis A, Corke K, Gill D, Wells M, Ziegler Heitbrock L, et al. Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am J Pathol. 2003;163:1233-43 pubmed
|
Seagroves T, Hadsell D, McManaman J, Palmer C, Liao D, McNulty W, et al. HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland. Development. 2003;130:1713-24 pubmed
|
Mandriota S, Turner K, Davies D, Murray P, Morgan N, Sowter H, et al. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 2002;1:459-68 pubmed
|
Fujii T, Otsuki T, Moriya T, Sakaguchi H, Kurebayashi J, Yata K, et al. Effect of hypoxia on human seminoma cells. Int J Oncol. 2002;20:955-62 pubmed
|
Tang T, Arbiser J, Brandt S. Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells. J Biol Chem. 2002;277:18365-72 pubmed
|
Albina J, Mastrofrancesco B, Vessella J, Louis C, Henry W, Reichner J. HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am J Physiol Cell Physiol. 2001;281:C1971-7 pubmed
|
Duyndam M, Hulscher T, Fontijn D, Pinedo H, Boven E. Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. J Biol Chem. 2001;276:48066-76 pubmed
|
Tacchini L, Dansi P, Matteucci E, Desiderio M. Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells. Carcinogenesis. 2001;22:1363-71 pubmed
|
Zhong H, De Marzo A, Laughner E, Lim M, Hilton D, Zagzag D, et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999;59:5830-5 pubmed
|