product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ABCA1 Antibody (HJ1) - BSA Free
catalog :
NB100-2068
quantity :
0.1 ml (also 0.025 ml)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HJ1
reactivity :
human, mouse, rat, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:2000; loading ...; fig 4e, 8b
Guix F, Capitán A, Casadomé Perales Á, Palomares Perez I, López Del Castillo I, Miguel V, et al. Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup. Life Sci Alliance. 2021;4: pubmed publisher
  • flow cytometry; mouse
de Souza Pinto R, Castilho G, Paim B, Machado Lima A, Inada N, Nakandakare E, et al. Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin. Lipids. 2012;47:443-50 pubmed publisher
  • western blot; domestic rabbit
Lu Y, Su M, Huang H, Lin Li -, Yuan C. Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide. Neurosci Lett. 2010;484:6-11 pubmed publisher
  • western blot; mouse
Wahrle S, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, et al. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008;118:671-82 pubmed publisher
Wilfahrt D, Philips R, Lama J, Kizerwetter M, Shapiro M, McCue S, et al. Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation. elife. 2021;10: pubmed publisher
Valtierra Alvarado M, Lugo Villarino G, Dueñas Arteaga F, González Contreras B, Lugo Sánchez A, Castañeda Delgado J, et al. Impact of type 2 diabetes on the capacity of human macrophages infected with Mycobacterium tuberculosis to modulate monocyte differentiation through a bystander effect. Immunol Cell Biol. 2021;99:1026-1039 pubmed publisher
Sun R, Fang P, Jiang J, Huang C, Wang J, Guo Q, et al. Insulin Rescued MCP-1-Suppressed Cholesterol Efflux to Large HDL2 Particles via ABCA1, ABCG1, SR-BI and PI3K/Akt Activation in Adipocytes. Cardiovasc Drugs Ther. 2021;: pubmed publisher
Valtierra Alvarado M, Castañeda Delgado J, Ramírez Talavera S, Lugo Villarino G, Dueñas Arteaga F, Lugo Sánchez A, et al. Type 2 diabetes mellitus metabolic control correlates with the phenotype of human monocytes and monocyte-derived macrophages. J Diabetes Complications. 2020;34:107708 pubmed publisher
Khodja Y, Samuels M. Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis. Lipids Health Dis. 2020;19:144 pubmed publisher
Levy D, de Melo T, Oliveira B, Paz J, de Freitas F, Reichert C, et al. 7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line. Biochem Biophys Rep. 2019;19:100604 pubmed publisher
Zhou Y, Miles J, Tavori H, Lin M, Khoshbouei H, Borchelt D, et al. PMP22 regulates cholesterol trafficking and ABCA1-mediated cholesterol efflux. J Neurosci. 2019;: pubmed publisher
Doğan S, Cerutti R, Benincá C, Brea Calvo G, Jacobs H, Zeviani M, et al. Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy. Cell Metab. 2018;28:764-775.e5 pubmed publisher
Li X, Zhu Y, Zhang H, Ma G, Wu G, Xiang A, et al. MicroRNA-106a-5p Inhibited C2C12 Myogenesis via Targeting PIK3R1 and Modulating the PI3K/AKT Signaling. Genes (Basel). 2018;9: pubmed publisher
Jheng J, Chen Y, Ao U, Chan D, Huang J, Hung K, et al. The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation. J Cachexia Sarcopenia Muscle. 2018;9:570-584 pubmed publisher
Yang Y, Yang Q, Yang J, Ma Y, Ding G. Angiotensin II induces cholesterol accumulation and injury in podocytes. Sci Rep. 2017;7:10672 pubmed publisher
Waldemer Streyer R, Reyes Ordoñez A, Kim D, Zhang R, Singh N, Chen J. Cxcl14 depletion accelerates skeletal myogenesis by promoting cell cycle withdrawal. NPJ Regen Med. 2017;2: pubmed publisher
Millington G, Elliott K, Chang Y, Chang C, Dlugosz A, Brugmann S. Cilia-dependent GLI processing in neural crest cells is required for tongue development. Dev Biol. 2017;424:124-137 pubmed publisher
Chuang H, Hsiao K, Chang H, Wu C, Pan H. The homeobox transcription factor Irxl1 negatively regulates MyoD expression and myoblast differentiation. FEBS J. 2014;281:2990-3003 pubmed publisher
Majmundar A, Skuli N, Mesquita R, Kim M, Yodh A, Nguyen McCarty M, et al. O(2) regulates skeletal muscle progenitor differentiation through phosphatidylinositol 3-kinase/AKT signaling. Mol Cell Biol. 2012;32:36-49 pubmed publisher
Scotti E, Hong C, Yoshinaga Y, Tu Y, Hu Y, Zelcer N, et al. Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists. Mol Cell Biol. 2011;31:1885-93 pubmed publisher
Bernardi H, Gay S, Fedon Y, Vernus B, Bonnieu A, Bacou F. Wnt4 activates the canonical ?-catenin pathway and regulates negatively myostatin: functional implication in myogenesis. Am J Physiol Cell Physiol. 2011;300:C1122-38 pubmed publisher
Sun Y, Ge Y, Drnevich J, Zhao Y, Band M, Chen J. Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis. J Cell Biol. 2010;189:1157-69 pubmed publisher
Wang J, Zhang Z, Chou C, Liang Y, Gu Y, Ma H. Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. Am J Physiol Renal Physiol. 2009;296:F284-90 pubmed publisher
Sell H, Eckardt K, Taube A, Tews D, Gurgui M, van Echten Deckert G, et al. Skeletal muscle insulin resistance induced by adipocyte-conditioned medium: underlying mechanisms and reversibility. Am J Physiol Endocrinol Metab. 2008;294:E1070-7 pubmed publisher
product information
brand :
Novus
MasterCode :
NB100-2068
SKU :
NB100-2068
product name :
ABCA1 Antibody (HJ1) - BSA Free
Description :
The ABCA1 Antibody (HJ1) - BSA Free from NB100-2068 is a nb100-2068 antibody to . This antibody reacts with abc transporters, astrocyte markers, cancer, cardiovascular biology, cellular markers, cholesterol metabolism, diabetes research, glia markers, golgi apparatus markers, lipid and metabolism, neuroscience, signal transduction.
target :
ABCA1
category :
Primary Antibodies
unit size :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
HJ1
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
50 kDa N-terminal extracellular loop of mouse ABCA1 Antibody (HJ1) UniProt# P41233]
isotype :
IgG2b Kappa
purity :
Protein G purified
species :
Human, Mouse, Rat
theoretical molecular weight :
250 kDa
gene symbol :
ABCA1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Western-Blot-NB100-2068-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Western-Blot-NB100-2068-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Immunohistochemistry-NB100-2068-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Immunohistochemistry-NB100-2068-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Flow-Cytometry-NB100-2068-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ABCA1-Antibody-(HJ1)-Flow-Cytometry-NB100-2068-img0010.jpg
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready
USD :
429 USD
alt names :
ABC-1, ABC1ATP-binding cassette transporter A1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A (ABC1), member 1, CERP, Cholesterol efflux regulatory protein, EC 2.7.7.8, EC 2.8.1.8, EC 3.6.3, EC 3.6.3.41, FLJ14958, HDLDT1, membrane-bound, MGC164864, MGC165011, TGDATP-binding cassette sub-family A member 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.