product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal Tankyrase 1 Antibody
catalog :
NB100-186R
quantity :
0.1 ml
price :
319.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
DyLight 550
reactivity :
human
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB100-186R
Product Name :
Rabbit Polyclonal Tankyrase 1 Antibody
List Price :
319.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
EC 2.4.2.30, PARP-5a, PARP5APARPL, pART5, Poly [ADP-ribose] polymerase 5A, Tankyrase I, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, tankyrase-1, TIN1TANK1, TINF1TNKS-1, TNKS1TRF1-interacting ankyrin-related ADP-ribose polymerase
Background :
The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
DyLight 550
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide made to a region of human Tankyrase within residues 250-350 [UniProt# O95271]. The actual peptide sequence is proprietary.
Localization :
Cytoplasmic. A minor proportion is also found at nuclear pore complexes and around the pericentriolar matrix of mitotic centromeres. During interphase, a small fraction of Tankyrase is found in the nucleus, associated with TRF1.
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human
Storage :
Store at 4C in the dark.
Swissprot Human :
O95271
Uses :
This Tankyrase antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where it recognizes an endogenous band at ~150 kDa in whole cell extract and a band at ~180 kDa in baculovirus-derived his-tagged protein.
Research Area :
Apoptosis, Chromatin Research, DNA Repair
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.