RNA Polymerase II/POLR2A [p Ser2] Antibody | Novus Biologicals NB100-1805 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

RNA Polymerase II/POLR2A [p Ser2] Antibody

catalog :

NB100-1805

quantity :

0.1 ml

price :

499 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Zhang B, Li Y, Zhang J, Wang Y, Liang C, Lu T, et al. ADAR1 links R-loop homeostasis to ATR activation in replication stress response. Nucleic Acids Res. 2023;51:11668-11687 pubmed publisher
Igarashi T, Mazevet M, Yasuhara T, Yano K, Mochizuki A, Nishino M, et al. An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress. Nat Commun. 2023;14:4991 pubmed publisher
Sch xfc tz M, Wangen C, Sommerer M, K xf6 gler M, Eickhoff J, Degenhart C, et al. Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency. Virus Res. 2023;335:199200 pubmed publisher
Brown R, Su X, Fair S, Wu K, Verra L, Jong R, et al. The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions. PLoS Biol. 2022;20:e3001940 pubmed publisher
Matos D, Zhang J, Ouyang J, Nguyen H, Genois M, Zou L. ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop. Mol Cell. 2020;77:514-527.e4 pubmed publisher
Tong Z, Mejía A, Veeranki O, Verma A, Correa A, Dokey R, et al. Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma. Ther Adv Med Oncol. 2019;11:1758835919864850 pubmed publisher
Tong Z, Chatterjee D, Deng D, Veeranki O, Mejía A, Ajani J, et al. Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma. Oncotarget. 2017;8:28696-28710 pubmed publisher

product information

master code :

NB100-1805

SKU :

NB100-1805

product name :

RNA Polymerase II/POLR2A [p Ser2] Antibody

unit size :

0.1 ml

description :

The RNA Polymerase II/POLR2A [p Ser2] Antibody from Novus is a rabbit polyclonal antibody to RNA Polymerase II/POLR2A. This antibody reacts with human,mouse,yeast. The RNA Polymerase II/POLR2A [p Ser2] Antibody has been validated for the following applications: Western Blot,Proximity Ligation Assay,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Single Cell Western.

target :

RNA Polymerase II/POLR2A

category :

Primary Antibodies

buffer :

TBS and 0.1% BSA

clonality :

Polyclonal

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Immunogen for this antibody was a phosphorylated synthetic peptide, which represented a portion of human RNA Polymerase II (GeneID 5430) around serine 2 of the C-terminal repeat YSPTSPS.

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Yeast

specificity :

RNA Polymerase 2 Phosphospecific [Ser2]

gene symbol :

POLR2A

Antibody validation :

Biological Validation

accessionNumbers :

P24928

applications :

Western Blot,Proximity Ligation Assay,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Single Cell Western

USD :

499 USD

alt names :

DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kdsubunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, EC 2.7.7.48, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, POLR2, POLRA, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, RNA Pol 2, RNA Polymerase 2, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RNAPII, RPB1, RPBh1, RpIILS, RPO2, RPOL2

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage