DDX21 Antibody - BSA Free | Novus Biologicals NB100-1718 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DDX21 Antibody - BSA Free

catalog :

NB100-1718

quantity :

0.1 ml (also 0.025 ml)

price :

419 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 11

Reference
Daigh L, Saha D, Rosenthal D, Ferrick K, Meyer T. Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence. Nat Commun. 2024;15:9181 pubmed publisher
Aryan F, Detr xe9 s D, Luo C, Kim S, Shah A, Bartusel M, et al. Nucleolus activity-dependent recruitment and biomolecular condensation by pH sensing. Mol Cell. 2023;83:4413-4423.e10 pubmed publisher
Gritti I, Basso V, Rinchai D, Corigliano F, Pivetti S, Gaviraghi M, et al. Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism. EMBO J. 2022;41:e108040 pubmed publisher
Karyka E, Berrueta Ramirez N, Webster C, Marchi P, Graves E, Godena V, et al. SMN-deficient cells exhibit increased ribosomal DNA damage. Life Sci Alliance. 2022;5: pubmed publisher
Li J, Wang D, Fang P, Pang Y, Zhou Y, Fang L, et al. DEAD-Box RNA Helicase 21 (DDX21) Positively Regulates the Replication of Porcine Reproductive and Respiratory Syndrome Virus via Multiple Mechanisms. Viruses. 2022;14: pubmed publisher
Freibaum B, Messing J, Yang P, Kim H, Taylor J. High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate. J Cell Biol. 2021;220: pubmed publisher
Wang X, Wu Z, Qin W, Sun T, Lu S, Li Y, et al. Long non-coding RNA ZFAS1 promotes colorectal cancer tumorigenesis and development through DDX21-POLR1B regulatory axis. Aging (Albany NY). 2020;12:22656-22687 pubmed publisher
Santoriello C, Sporrij A, Yang S, Flynn R, Henriques T, Dorjsuren B, et al. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nat Cell Biol. 2020;22:372-379 pubmed publisher
Shao Z, Flynn R, Crowe J, Zhu Y, Liang J, Jiang W, et al. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature. 2020;579:291-296 pubmed publisher
Calo E, Gu B, Bowen M, Aryan F, Zalc A, Liang J, et al. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. 2018;554:112-117 pubmed publisher
Song C, Hotz Wagenblatt A, Voit R, Grummt I. SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability. Genes Dev. 2017;31:1370-1381 pubmed publisher

product information

master code :

NB100-1718

SKU :

NB100-1718

product name :

DDX21 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The DDX21 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to DDX21. This antibody reacts with human,mouse,porcine,zebrafish,fish - danio rerio (zebrafish). The DDX21 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Chemotaxis,IF/IHC,Knockdown Validated,Chromatin Immunoprecipitation,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP).

target :

DDX21

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue 725 and the C-terminus (residue 783) of human DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 21 using the numbering given in entry NP_004719.2 (GeneID 9188).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Porcine,Zebrafish,Fish - Danio rerio (Zebrafish)

theoretical molecular weight :

87 kDa

gene symbol :

DDX21

accessionNumbers :

Q9NR30

applications :

Immunocytochemistry/ Immunofluorescence,Chemotaxis,IF/IHC,Western Blot,Knockdown Validated,Chromatin Immunoprecipitation,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP)

USD :

419 USD

alt names :

DEAD (Asp-Glu-Ala-Asp) box polypeptide 21, DEAD box protein 21, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21, DKFZp686F21172, EC 3.6.1, EC 3.6.4.13, Gu protein, GUA, gu-alpha, GURDB, nucleolar RNA helicase 2, Nucleolar RNA helicase Gu, Nucleolar RNA helicase II, RH II/Gu, RH-II/GU, RH-II/GuA, RNA helicase II/Gu alpha

storage :

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage