product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MGMT Antibody (MT 23.2) - BSA Free
catalog :
NB100-168
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MT 23.2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 19
Reference |
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Lylo V, Matsevich L, Kotsarenko E, Babenko L, Korneliuk A, Sukhorada E, et al. [Induction of repair enzyme O6-methylguanine-DNA methyltransferase gene expression under the influence of cytokine EMAP II in human cells in vitro]. Tsitol Genet. 2011;45:53-60 pubmed
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Cai S, Xu Y, Cooper R, Ferkowicz M, Hartwell J, Pollok K, et al. Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents. Cancer Res. 2005;65:3319-27 pubmed
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Zuo C, Ai L, Ratliff P, Suen J, Hanna E, Brent T, et al. O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2004;13:967-75 pubmed
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Roth T, Xu Y, Luo M, Kelley M. Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection. Cancer Gene Ther. 2003;10:603-10 pubmed
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Liu L, Spiro T, Qin X, Majka S, Haaga J, Schupp J, et al. Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine. Clin Cancer Res. 2001;7:2318-24 pubmed
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product information
master code :
NB100-168
SKU :
NB100-168
product name :
MGMT Antibody (MT 23.2) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The MGMT Antibody (MT 23.2) - BSA Free from Novus is a mouse monoclonal antibody to MGMT. This antibody reacts with human,mouse,mouse (negative). The MGMT Antibody (MT 23.2) - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Immunohistochemistry,Flow (Intracellular),Simple Western,CyTOF-ready,Immunocytochemistry/ Immunofluorescence.
target :
MGMT
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
MT 23.2
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human MGMT (O6-methylguanine-DNA methyltransferase) purified from E. coli [UniProt# P16455]
isotype :
IgG2b
purity :
Protein G purified
species :
Human,Mouse,Mouse (Negative)
theoretical molecular weight :
24 kDa
gene symbol :
MGMT
accessionNumbers :
P16455
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Immunohistochemistry,Flow (Intracellular),Simple Western,CyTOF-ready,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
6-O-methylguanine-DNA methyltransferase, EC 2.1.1.63, methylated-DNA--protein-cysteine methyltransferase, methylguanine-DNA methyltransferase, O-6-methylguanine-DNA methyltransferase, O6-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information

Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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