product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
POMC Antibody
catalog :
NB100-1533
quantity :
0.1 mg
price :
459 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Reference
Mun S, Lee C, Kim H, Kim J, Lee H, Yang J, et al. Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons. Cell Rep. 2023;42:112746 pubmed publisher
Wang Z, Khor S, Cai D. Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice. J Biol Chem. 2019;294:4946-4955 pubmed publisher
Mandal S, Briski K. Hindbrain dorsal vagal complex AMPK controls hypothalamic gluco-regulatory transmitter and counter-regulatory hormone responses to hypoglycemia. Brain Res Bull. 2019;144:171-179 pubmed publisher
Shakya M, Shrestha P, Briski K. Hindbrain 5'-Adenosine Monophosphate-activated Protein Kinase Mediates Short-term Food Deprivation Inhibition of the Gonadotropin-releasing Hormone-Luteinizing Hormone Axis: Role of Nitric Oxide. Neuroscience. 2018;383:46-59 pubmed publisher
Kim G, Shi G, Somlo D, Haataja L, Song S, Long Q, et al. Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity. J Clin Invest. 2018;128:1125-1140 pubmed publisher
Klasvogt S, Zuschratter W, Schmidt A, Kröber A, Vorwerk S, Wolter R, et al. Air-liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2. Cell Death Discov. 2017;3:17001 pubmed publisher
Trebak F, Dubuc I, Arabo A, Alaoui A, Boukhzar L, Maucotel J, et al. A potential role for the secretogranin II-derived peptide EM66 in the hypothalamic regulation of feeding behaviour. J Neuroendocrinol. 2017;29: pubmed publisher
product information
master code :
NB100-1533
SKU :
NB100-1533
product name :
POMC Antibody
unit size :
0.1 mg
description :
The POMC Antibody from Novus is a goat polyclonal antibody to POMC. This antibody reacts with human,mouse,ovine,porcine,rat,sheep. The POMC Antibody has been validated for the following applications: IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA.
target :
POMC
category :
Primary Antibodies
buffer :
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
clonality :
Polyclonal
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Goat
immunogen :
Peptide with sequence C-NAIIKNAYKKGE corresponding to C-Terminus according to NP_000930.1, NP_001030333.1.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Ovine,Porcine,Rat,Sheep
theoretical molecular weight :
29.4 kDa
gene symbol :
POMC
accessionNumbers :
P01189
applications :
IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA
USD :
459 USD
alt names :
ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte-stimulating hormone, alpha-MSH, beta-endorphin, beta-LPH, beta-melanocyte-stimulating hormone, beta-MSH, CLIP, corticotropin-like intermediary peptide, corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, LPH, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, MSH, NPP, POC, pro-ACTH-endorphin, proopiomelanocortin, pro-opiomelanocortin, proopiomelanocortin preproprotein
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.