| Reference |
|---|
Conway J, Gillani R, Crowdis J, Reardon B, Park J, Han S, et al. Somatic structural variants drive distinct modes of oncogenesis in melanoma. J Clin Invest. 2024;134: pubmed publisher |
Wong H, Luperchio A, Riley S, Salamango D. Inhibition of ATM-directed antiviral responses by HIV-1 Vif. PLoS Pathog. 2023;19:e1011634 pubmed publisher |
Park S, Kwon M, Ju E, Shin S, Park J, Ko E, et al. Targeting phosphomevalonate kinase enhances radiosensitivity via ubiquitination of the replication protein A1 in lung cancer cells. Cancer Sci. 2023;114:3583-3594 pubmed publisher |
Boichuk S, Bikinieva F, Valeeva E, Dunaev P, Vasileva M, Kopnin P, et al. Establishment and Characterization of Multi-Drug Resistant p53-Negative Osteosarcoma SaOS-2 Subline. Diagnostics (Basel). 2023;13: pubmed publisher |
Nechay M, Wang D, Kleiner R. Inhibition of nucleolar transcription by oxaliplatin involves ATM/ATR kinase signaling. Cell Chem Biol. 2023;30:906-919.e4 pubmed publisher |
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, et al. The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response. Cell Rep. 2022;41:111819 pubmed publisher |
Mann A, Ramirez Otero M, De Antoni A, Hanthi Y, Sannino V, Baldi G, et al. POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps. Mol Cell. 2022;82:4218-4231.e8 pubmed publisher |
Ferrari S, Jacob A, Cesana D, Laugel M, Beretta S, Varesi A, et al. Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells. Cell Stem Cell. 2022;29:1428-1444.e9 pubmed publisher |
Berthault N, Bergam P, Pereira F, Girard P, Dutreix M. Inhibition of DNA Repair by Inappropriate Activation of ATM, PARP, and DNA-PK with the Drug Agonist AsiDNA. Cells. 2022;11: pubmed publisher |
Park D, Gharghabi M, Reczek C, Plow R, Yungvirt C, Aldaz C, et al. Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice. Int J Mol Sci. 2022;23: pubmed publisher |
Fitieh A, Locke A, Mashayekhi F, Khaliqdina F, Sharma A, Ismail I. BMI-1 regulates DNA end resection and homologous recombination repair. Cell Rep. 2022;38:110536 pubmed publisher |
Park D, Gharghabi M, Schrock M, Plow R, Druck T, Yungvirt C, et al. Interaction of Wwox with Brca1 and associated complex proteins prevents premature resection at double-strand breaks and aberrant homologous recombination. DNA Repair (Amst). 2022;110:103264 pubmed publisher |
Scott W, Dhanji E, Dyakov B, Dreseris E, Asa J, Grange L, et al. ATRX proximal protein associations boast roles beyond histone deposition. PLoS Genet. 2021;17:e1009909 pubmed publisher |
Bakr A, Hey J, Sigismondo G, Liu C, Sadik A, Goyal A, et al. ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition. Nucleic Acids Res. 2021;49:11666-11689 pubmed publisher |
Herok M, Wawrzynow B, Maluszek M, Olszewski M, Zylicz A, Zylicz M. Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance. Cancers (Basel). 2021;13: pubmed publisher |
Isobe S, Hiraga S, Nagao K, Sasanuma H, Donaldson A, Obuse C. Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action. Cell Rep. 2021;36:109383 pubmed publisher |
Na J, Newman J, Then C, Syed J, Vendrell I, Torrecilla I, et al. SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells. Cell Death Dis. 2021;12:165 pubmed publisher |
Sharma S, Anand R, Zhang X, Francia S, Michelini F, Galbiati A, et al. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends. Cell Rep. 2021;34:108565 pubmed publisher |
Chansel Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, et al. A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans. Cell Rep. 2020;33:108559 pubmed publisher |
Herrmann C, Dybas J, Liddle J, Price A, Hayer K, Lauman R, et al. Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing. Nat Microbiol. 2020;5:1217-1231 pubmed publisher |
Howard S, Ceppi I, Anand R, Geiger R, Cejka P. The internal region of CtIP negatively regulates DNA end resection. Nucleic Acids Res. 2020;48:5485-5498 pubmed publisher |
Ragamin A, Yigit G, Bousset K, Beleggia F, Verheijen F, de Wit M, et al. Human RAD50 deficiency: Confirmation of a distinctive phenotype. Am J Med Genet A. 2020;182:1378-1386 pubmed publisher |
Qi F, Meng Q, Hayashi I, Kobayashi J. FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. J Radiat Res. 2020;61:368-375 pubmed publisher |
Mooser C, Symeonidou I, Leimbacher P, Ribeiro A, Shorrocks A, Jungmichel S, et al. Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation. Nat Commun. 2020;11:123 pubmed publisher |
Völkening L, Vatselia A, Asgedom G, Bastians H, Lavin M, Schindler D, et al. RAD50 regulates mitotic progression independent of DNA repair functions. FASEB J. 2020;34:2812-2820 pubmed publisher |
Yoshimura Y. Increased error-free DNA repair gene expression through reprogramming in human iPS cells. Regen Ther. 2019;11:101-105 pubmed publisher |
Korsholm L, Gál Z, Lin L, Quevedo O, Ahmad D, Dulina E, et al. Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair. Nucleic Acids Res. 2019;47:8019-8035 pubmed publisher |
Leimbacher P, Jones S, Shorrocks A, De Marco Zompit M, Day M, Blaauwendraad J, et al. MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis. Mol Cell. 2019;74:571-583.e8 pubmed publisher |
Qin B, Yu J, Nowsheen S, Wang M, Tu X, Liu T, et al. UFL1 promotes histone H4 ufmylation and ATM activation. Nat Commun. 2019;10:1242 pubmed publisher |
Erickson K, Garcea R. Viral replication centers and the DNA damage response in JC virus-infected cells. Virology. 2019;528:198-206 pubmed publisher |
Anand R, Jasrotia A, Bundschuh D, Howard S, Ranjha L, Stucki M, et al. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation. EMBO J. 2019;38: pubmed publisher |
Suh K, Ryu H, Lee K, Kim H, Min A, Kim T, et al. Prognostic effects of abnormal DNA damage response protein expression in breast cancer. Breast Cancer Res Treat. 2019;175:117-127 pubmed publisher |
Lamarche B, Orazio N, Goben B, Meisenhelder J, You Z, Weitzman M, et al. Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays. DNA Repair (Amst). 2019;74:80-90 pubmed publisher |
Gao Y, Kardos J, Yang Y, Tamir T, Mutter Rottmayer E, Weissman B, et al. The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells. Sci Rep. 2018;8:15304 pubmed publisher |
Gustafsson N, Färnegårdh K, Bonagas N, Ninou A, Groth P, Wiita E, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018;9:3872 pubmed publisher |
Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed publisher |
Pancholi N, Weitzman M. Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex. Virology. 2018;518:221-231 pubmed publisher |
Lee K, Im J, Shibata E, Dutta A. ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks. Mol Cell. 2017;68:61-75.e5 pubmed publisher |
Moyal L, Goldfeiz N, Gorovitz B, Rephaeli A, Tal E, Tarasenko N, et al. AN-7, a butyric acid prodrug, sensitizes cutaneous T-cell lymphoma cell lines to doxorubicin via inhibition of DNA double strand breaks repair. Invest New Drugs. 2018;36:1-9 pubmed publisher |
Ward T, McHugh P, Durant S. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS ONE. 2017;12:e0179278 pubmed publisher |
Burke R, Marcus J, Orth J. Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells. Oncotarget. 2017;8:39460-39475 pubmed publisher |
Mariggiò G, Koch S, Zhang G, Weidner Glunde M, Rückert J, Kati S, et al. Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. PLoS Pathog. 2017;13:e1006335 pubmed publisher |
Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang Akiyama Q. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein. J Radiat Res. 2017;58:487-494 pubmed publisher |
Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017;7:44662 pubmed publisher |
Campos León K, Wijendra K, Siddiqa A, Pentland I, Feeney K, Knapman A, et al. Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication. J Virol. 2017;91: pubmed publisher |
