| Reference |
|---|
Lee S, Lee S, Choi N, Kim J, Kweon J, Miller K, et al. PCAF promotes R-loop resolution via histone acetylation. Nucleic Acids Res. 2024;52:8643-8660 pubmed publisher |
Tang Z, Liang Z, Zhang B, Xu X, Li P, Li L, et al. MRE11 is essential for the long-term viability of undifferentiated spermatogonia. Cell Prolif. 2024;57:e13685 pubmed publisher |
Garc xed a Rodr xed guez N, Dom xed nguez Garc xed a I, Dom xed nguez P xe9 rez M, Huertas P. EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells. Nucleic Acids Res. 2024;52:6376-6391 pubmed publisher |
Ubieto Capella P, Xim xe9 nez Emb xfa n P, Gim xe9 nez Llorente D, Losada A, Mu xf1 oz J, M xe9 ndez J. A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation. Cell Rep. 2024;43:114024 pubmed publisher |
Rubio Contreras D, G xf3 mez Herreros F. TDP1 suppresses chromosomal translocations and cell death induced by abortive TOP1 activity during gene transcription. Nat Commun. 2023;14:6940 pubmed publisher |
Ip W, Tatham M, Krohne S, Gruhne J, Melling M, Meyer T, et al. Adenovirus E1B-55K controls SUMO-dependent degradation of antiviral cellular restriction factors. J Virol. 2023;97:e0079123 pubmed publisher |
Herrera L, Johnson R, McGlynn K, Gibbs Z, Davis A, Whitehurst A. The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks. J Biol Chem. 2023;299:105348 pubmed publisher |
Marone R, Landmann E, Devaux A, Lepore R, Seyres D, Zuin J, et al. Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy. J Exp Med. 2023;220: pubmed publisher |
Park S, Kim N, Kang N, Ryu E, Lee E, Ra J, et al. Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination. Nucleic Acids Res. 2023;51:10519-10535 pubmed publisher |
Deshpande R, Marin Gonzalez A, Barnes H, Woolley P, Ha T, Paull T. Genome-wide analysis of DNA-PK-bound MRN cleavage products supports a sequential model of DSB repair pathway choice. Nat Commun. 2023;14:5759 pubmed publisher |
Einig E, Jin C, Andrioletti V, Macek B, Popov N. RNAPII-dependent ATM signaling at collisions with replication forks. Nat Commun. 2023;14:5147 pubmed publisher |
Liu C, Wang L, Li Y, Guo M, Hu J, Wang T, et al. RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis. Nucleic Acids Res. 2023;51:7357-7375 pubmed publisher |
Sachsenweger J, Jansche R, Merk T, Heitmeir B, Deniz M, Faust U, et al. ABRAXAS1 orchestrates BRCA1 activities to counter genome destabilizing repair pathways-lessons from breast cancer patients. Cell Death Dis. 2023;14:328 pubmed publisher |
G xf6 ttig L, Wei xdf C, Stubbe M, Hanrieder L, Hofmann S, Grodziecki A, et al. Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression. MBio. 2023;14:e0347822 pubmed publisher |
Zou R, Liu Y, Gaido O, Konig M, Mog B, Shen L, et al. Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq. Nat Methods. 2023;20:706-713 pubmed publisher |
Pollina E, Gilliam D, Landau A, Lin C, Pajarillo N, Davis C, et al. A NPAS4-NuA4 complex couples synaptic activity to DNA repair. Nature. 2023;614:732-741 pubmed publisher |
Herrera L, McGlynn K, Gibbs Z, Davis A, Whitehurst A. The Cancer Testes Antigen, HORMAD1, is a Tumor-Specific Replication Fork Protection Factor. bioRxiv. 2023;: pubmed publisher |
Lazarchuk P, Nguyen V, Brunon S, Pavlova M, Sidorova J. Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells. Front Mol Biosci. 2022;9:1048726 pubmed publisher |
Jeong H, Wie M, Baek I, Sohn G, Um S, Lee S, et al. TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11. Cells. 2022;11: pubmed publisher |
Wang L, Liu C, Wei H, Ouyang Y, Dong M, Zhang R, et al. Testis electroporation coupled with autophagy inhibitor to treat non-obstructive azoospermia. Mol Ther Nucleic Acids. 2022;30:451-464 pubmed publisher |
Price A, Steinbock R, Lauman R, Charman M, Hayer K, Kumar N, et al. Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts. PLoS Pathog. 2022;18:e1010797 pubmed publisher |
Qi L, Chakravarthy R, Li M, Deng C, Li R, Hu Y. Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop. iScience. 2022;25:104944 pubmed publisher |
M xf6 ller L, Aird E, Schr xf6 der M, Kobel L, Kissling L, van de Venn L, et al. Recursive Editing improves homology-directed repair through retargeting of undesired outcomes. Nat Commun. 2022;13:4550 pubmed publisher |
Zhang H, Xiong Y, Su D, Wang C, Srivastava M, Tang M, et al. TDP1-independent pathways in the process and repair of TOP1-induced DNA damage. Nat Commun. 2022;13:4240 pubmed publisher |
Fowler F, Chen B, Zolnerowich N, Wu W, Pavani R, Paiano J, et al. DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells. elife. 2022;11: pubmed publisher |
Chakraborty S, Singh M, Pandita R, Singh V, Lo C, Leonard F, et al. Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks. iScience. 2022;25:104142 pubmed publisher |
Gnedina O, Morshneva A, Skvortsova E, Igotti M. HDAC Inhibitor Sodium Butyrate Attenuates the DNA Repair in Transformed but Not in Normal Fibroblasts. Int J Mol Sci. 2022;23: pubmed publisher |
Zhang C, Zhou B, Gu F, Liu H, Wu H, Yao F, et al. Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation. Mol Cell. 2022;82:1297-1312.e8 pubmed publisher |
Chen C, Bridge E. DNA-PK phosphorylation at Ser2056 during adenovirus E4 mutant infection is promoted by viral DNA replication and independent of the MRN complex. Virology. 2022;565:82-95 pubmed publisher |
Ding M, Qing X, Zhang G, Baade B xfc ttner C, Gruber R, Lu H, et al. The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons. Front Aging Neurosci. 2021;13:786199 pubmed publisher |
Mirzaei R, Gordon A, Zemp F, Kumar M, Sarkar S, Luchman H, et al. PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFκB pathway. Sci Adv. 2021;7:eabh2148 pubmed publisher |
Graziano S, Coll Bonfill N, Teodoro Castro B, Kuppa S, Jackson J, Shashkova E, et al. Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability. J Biol Chem. 2021;297:101301 pubmed publisher |
Paiano J, Zolnerowich N, Wu W, Pavani R, Wang C, Li H, et al. Role of 53BP1 in end protection and DNA synthesis at DNA breaks. Genes Dev. 2021;35:1356-1367 pubmed publisher |
Chen B, Wang Y, Tubbs A, Zong D, Fowler F, Zolnerowich N, et al. LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. elife. 2021;10: pubmed publisher |
Dybas J, Lum K, Kulej K, Reyes E, Lauman R, Charman M, et al. Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes. mSystems. 2021;:e0046821 pubmed publisher |
Kaul Z, Cheung C, Bhargava P, Sari A, Yu Y, Huifu H, et al. Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells. Sci Rep. 2021;11:17052 pubmed publisher |
Wang J, Liu R, Wang Y, Mo H, Niu Y, Xu Q, et al. Repression of the miR-627-5p by histone deacetylase 3 contributes to hypoxia-induced hepatocellular carcinoma progression. J Cancer. 2021;12:5320-5330 pubmed publisher |
Wu X, Wang B. Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage. Nat Commun. 2021;12:4373 pubmed publisher |
Chakraborty P, Hiom K. DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination. Nat Commun. 2021;12:4126 pubmed publisher |
Liu C, Liu H, Zhang H, Wang L, Li M, Cai F, et al. Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans. EMBO J. 2021;40:e106864 pubmed publisher |
Mukherjee J, Pandita A, Kamalakar C, Johannessen T, Ohba S, Tang Y, et al. A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells. Sci Transl Med. 2021;13: pubmed publisher |
Cabral J, Cushman C, Sodroski C, Knipe D. ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection. PLoS Pathog. 2021;17:e1009567 pubmed publisher |
Schep R, Brinkman E, Leemans C, Vergara X, van der Weide R, Morris B, et al. Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance. Mol Cell. 2021;81:2216-2230.e10 pubmed publisher |
Zou R, Liu Y, Wu B, Ha T. Cas9 deactivation with photocleavable guide RNAs. Mol Cell. 2021;81:1553-1565.e8 pubmed publisher |
Somyajit K, Spies J, Coscia F, Kirik U, Rask M, Lee J, et al. Homology-directed repair protects the replicating genome from metabolic assaults. Dev Cell. 2021;56:461-477.e7 pubmed publisher |
Mertens M, Knipe D. Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses. MBio. 2021;12: pubmed publisher |
Dar A, Sawada K, Dybas J, Moser E, Lewis E, Park E, et al. The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA. PLoS Biol. 2021;19:e3001041 pubmed publisher |
Whelan D, Lee W, Marks F, Kong Y, Yin Y, Rothenberg E. Super-resolution visualization of distinct stalled and broken replication fork structures. PLoS Genet. 2020;16:e1009256 pubmed publisher |
Zhou Z, Kirtay M, Schneble N, Yakoub G, Ding M, Rüdiger T, et al. NBS1 interacts with Notch signaling in neuronal homeostasis. Nucleic Acids Res. 2020;48:10924-10939 pubmed publisher |
Lan W, Santofimia Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, et al. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. JCI Insight. 2020;5: pubmed publisher |
Volcic M, Sparrer K, Koepke L, Hotter D, Sauter D, Stürzel C, et al. Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1. Nat Microbiol. 2020;5:1247-1261 pubmed publisher |
Herrmann C, Dybas J, Liddle J, Price A, Hayer K, Lauman R, et al. Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing. Nat Microbiol. 2020;5:1217-1231 pubmed publisher |
Rainey M, Quinlan A, Cazzaniga C, Mijic S, Martella O, Krietsch J, et al. CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO Rep. 2020;:e48920 pubmed publisher |
Hofmann S, Mai J, Masser S, Groitl P, Herrmann A, Sternsdorf T, et al. ATO (Arsenic Trioxide) Effects on Promyelocytic Leukemia Nuclear Bodies Reveals Antiviral Intervention Capacity. Adv Sci (Weinh). 2020;7:1902130 pubmed publisher |
Wienert B, Wyman S, Yeh C, Conklin B, Corn J. CRISPR off-target detection with DISCOVER-seq. Nat Protoc. 2020;15:1775-1799 pubmed publisher |
Nath S, Nagaraju G. FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks. PLoS Genet. 2020;16:e1008701 pubmed publisher |
Qi F, Meng Q, Hayashi I, Kobayashi J. FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. J Radiat Res. 2020;61:368-375 pubmed publisher |
Vancevska A, Ahmed W, Pfeiffer V, Feretzaki M, Boulton S, Lingner J. SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres. EMBO J. 2020;39:e102668 pubmed publisher |
Paiano J, Wu W, Yamada S, Sciascia N, Callen E, Paola Cotrim A, et al. ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis. Nat Commun. 2020;11:857 pubmed publisher |
Park S, Kang N, Song E, Wie M, Lee E, Hwang S, et al. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nat Commun. 2019;10:5718 pubmed publisher |
Pan X, Chen Y, Biju B, Ahmed N, Kong J, Goldenberg M, et al. FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. Sci Rep. 2019;9:19110 pubmed publisher |
Mladenov E, Staudt C, Soni A, Murmann Konda T, Siemann Loekes M, Iliakis G. Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52. Nucleic Acids Res. 2020;48:1905-1924 pubmed publisher |
Hanlon K, Meltzer J, Buzhdygan T, Cheng M, Sena Esteves M, Bennett R, et al. Selection of an Efficient AAV Vector for Robust CNS Transgene Expression. Mol Ther Methods Clin Dev. 2019;15:320-332 pubmed publisher |
Scherthan H, Lee J, Maus E, Schumann S, Muhtadi R, Chojowski R, et al. Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223. Cancers (Basel). 2019;11: pubmed publisher |
Fievet A, Bellanger D, Zahed L, Burglen L, Derrien A, Dubois d Enghien C, et al. DNA repair functional analyses of NBN hypomorphic variants associated with NBN-related infertility. Hum Mutat. 2020;41:608-618 pubmed publisher |
Porebski B, Wild S, Kummer S, Scaglione S, Gaillard P, Gari K. WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage. iScience. 2019;21:31-41 pubmed publisher |
Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, et al. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. Mol Cell. 2019;: pubmed publisher |
Yoshimura Y. Increased error-free DNA repair gene expression through reprogramming in human iPS cells. Regen Ther. 2019;11:101-105 pubmed publisher |
Velichko A, Petrova N, Luzhin A, Strelkova O, Ovsyannikova N, Kireev I, et al. Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription. Nucleic Acids Res. 2019;: pubmed publisher |
Afzal S, Garg S, Ishida Y, Terao K, Kaul S, Wadhwa R. Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin. Mar Drugs. 2019;17: pubmed publisher |
Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher |
Li C, Mahon C, Sweeney N, Verschueren E, Kantamani V, Li D, et al. PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis. Cell Rep. 2019;26:1333-1343.e7 pubmed publisher |
Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher |
Gustafsson N, Färnegårdh K, Bonagas N, Ninou A, Groth P, Wiita E, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018;9:3872 pubmed publisher |
Hung P, Johnson B, Chen B, Byrum A, Bredemeyer A, Yewdell W, et al. MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Mol Cell. 2018;71:332-342.e8 pubmed publisher |
Müncheberg S, Hay R, Ip W, Meyer T, Weis C, Brenke J, et al. E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression. J Virol. 2018;92: pubmed publisher |
Vadnais C, Chen R, Fraszczak J, Yu Z, Boulais J, Pinder J, et al. GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1. Nat Commun. 2018;9:1418 pubmed publisher |
Pancholi N, Weitzman M. Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex. Virology. 2018;518:221-231 pubmed publisher |
Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang Akiyama Q. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein. J Radiat Res. 2017;58:487-494 pubmed publisher |
Morales A, Carrero J, Hung P, Tubbs A, Andrews J, Edelson B, et al. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages. elife. 2017;6: pubmed publisher |
Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher |
Speiseder T, Hofmann Sieber H, Rodriguez E, Schellenberg A, Akyüz N, Dierlamm J, et al. Efficient Transformation of Primary Human Mesenchymal Stromal Cells by Adenovirus Early Region 1 Oncogenes. J Virol. 2017;91: pubmed publisher |
Cirilli M, Bereshchenko O, Ermakova O, Nerlov C. Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis. Biochim Biophys Acta Gen Subj. 2017;1861:467-476 pubmed publisher |
