| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; fig 3
- western blot knockout validation; mouse; fig 3
| Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 6b
| Shao R, Zhang Z, Xu Z, Ouyang H, Wang L, Ouyang H, et al. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair. Bone Res. 2021;9:30 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 5a, 7a
- immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5e
| Turgu B, Zhang F, El Naggar A, Negri G, Kogler M, Tortola L, et al. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021;40:1988-2001 pubmed publisher |
- immunohistochemistry; mouse; 1:200; loading ...; fig 8e
| Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 5a
| Dmitrieva N, Walts A, Nguyen D, Grubb A, Zhang X, Wang X, et al. Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome. J Clin Invest. 2020;130:4167-4181 pubmed publisher |
- western blot; mouse; loading ...; fig 4b
| Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Rep. 2018;25:3194-3203.e4 pubmed publisher |
- western blot; human; 1:500; fig s4e
| Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher |
- chromatin immunoprecipitation; mouse; loading ...; fig 3a
| Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 4f
| Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed publisher |
- immunohistochemistry - paraffin section; dogs; 1:500; fig 5
| Spitzbarth I, Lempp C, Kegler K, Ulrich R, Kalkuhl A, Deschl U, et al. Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis. Brain Behav. 2016;6:e00472 pubmed publisher |
- chromatin immunoprecipitation; mouse
| Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher |
- immunoprecipitation; human; 1:200; loading ...; fig 2f
- western blot; human; 1:1000; loading ...; fig 2f
| Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed publisher |
- western blot; human; fig 1
| de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed publisher |
- western blot; rat
- western blot; mouse; 1:600
| Hung Y, Chang S, Huang C, Yin J, Hwang C, Yang L, et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol Neurobiol. 2016;53:793-809 pubmed publisher |
| Singh A, Cheng D, Swaminathan J, Yang Y, Zheng Y, Gordon N, et al. REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. Sci Rep. 2024;14:13596 pubmed publisher |
| Liu X, Tang J, Wang Z, Zhu C, Deng H, Sun X, et al. Oxygen enhances antiviral innate immunity through maintenance of EGLN1-catalyzed proline hydroxylation of IRF3. Nat Commun. 2024;15:3533 pubmed publisher |
| Verhaar N, Grages A, Sauer F, Geiger T, Reineking W, Hewicker Trautwein M, et al. Measuring tissue oxygen saturation in the orad intestinal segment during equine colic surgery may aid in predicting the occurrence of postoperative ileus. Am J Vet Res. 2024;85: pubmed publisher |
| Murphy D, Osteicochea D, Atkins A, Sannes C, McClarnon Z, Adjei I. Optimizing Oxygen-Production Kinetics of Manganese Dioxide Nanoparticles Improves Hypoxia Reversal and Survival in Mice with Bone Metastases. Mol Pharm. 2024;21:1125-1136 pubmed publisher |
| M xfc cke M, El Bali N, Schwarzkopf K, Uschner F, Kraus N, Eberle L, et al. The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure. Int J Mol Sci. 2024;25: pubmed publisher |
| Liao Q, Deng H, Wang Z, Yu G, Zhu C, Jia S, et al. Deletion of prolyl hydroxylase domain-containing enzyme 3 (phd3) in zebrafish facilitates hypoxia tolerance. J Biol Chem. 2023;299:105420 pubmed publisher |
| Wang T, Dong Y, Huang Z, Zhang G, Zhao Y, Yao H, et al. Antioxidants stimulate BACH1-dependent tumor angiogenesis. J Clin Invest. 2023;133: pubmed publisher |
| Chen R, Wang H, Zheng C, Zhang X, Li L, Wang S, et al. Polo-like kinase 1 promotes pulmonary hypertension. Respir Res. 2023;24:204 pubmed publisher |
| Liao Q, Zhu C, Sun X, Wang Z, Chen X, Deng H, et al. Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance. J Biol Chem. 2023;:105074 pubmed publisher |
| Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, et al. Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection. Microbiol Spectr. 2023;11:e0455422 pubmed publisher |
| Schw xf6 rer S, Cimino F, Ros M, Tsanov K, Ng C, Lowe S, et al. Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell-Derived Cytokines. Cancer Res. 2023;83:1596-1610 pubmed publisher |
| Verhaar N, de Buhr N, von K xf6 ckritz Blickwede M, D xfc mmer K, Hewicker Trautwein M, Pfarrer C, et al. Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia. Front Vet Sci. 2023;10:1110019 pubmed publisher |
| Kishimoto H, Nakano T, Torisu K, Tokumoto M, Uchida Y, Yamada S, et al. Indoxyl sulfate induces left ventricular hypertrophy via the AhR-FGF23-FGFR4 signaling pathway. Front Cardiovasc Med. 2023;10:990422 pubmed publisher |
| Lee E, Lee E, Kong E, Chon H, Llaiqui Condori M, Park C, et al. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone. Exp Mol Med. 2023;55:470-484 pubmed publisher |
| Barone F, Urb xe9 S, Clague M. Segregation of pathways leading to pexophagy. Life Sci Alliance. 2023;6: pubmed publisher |
| de Oliveira Freitas Machado C, Schafranek M, Br xfc ggemann M, Hern xe1 ndez Ca xf1 xe1 s M, Keller M, Di Liddo A, et al. Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia. Nucleic Acids Res. 2023;51:870-890 pubmed publisher |
| E G, Sun B, Liu B, Xu G, He S, Wang Y, et al. Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2. Brain Res Bull. 2023;192:36-46 pubmed publisher |
| Do T, Lau J, Sun C, Liu S, Kha K, Lim S, et al. Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras. Sci Adv. 2022;8:eabq2216 pubmed publisher |
| La Salvia A, Carletti R, Verrico M, Feola T, Puliani G, Bassi M, et al. Angioside: The role of Angiogenesis and Hypoxia in Lung Neuroendocrine Tumours According to Primary Tumour Location in Left or Right Parenchyma. J Clin Med. 2022;11: pubmed publisher |
| Yang W, Wu W, Zhao Y, Li Y, Zhang C, Zhang J, et al. Caveolin-1 suppresses hippocampal neuron apoptosis via the regulation of HIF1α in hypoxia in naked mole-rats. Cell Biol Int. 2022;46:2060-2074 pubmed publisher |
| Tikhonova M, Maslov N, Bashirzade A, Nehoroshev E, Babchenko V, Chizhova N, et al. A Novel Laser-Based Zebrafish Model for Studying Traumatic Brain Injury and Its Molecular Targets. Pharmaceutics. 2022;14: pubmed publisher |
| Li X, Wang L, Qin X, Chen X, Li L, Huang Z, et al. Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models. Cell Death Discov. 2022;8:323 pubmed publisher |
| Suresh M, Yalamanchili G, Rao T, Aktay S, Kralovich A, Shah Y, et al. Hypoxia-inducible factor (HIF)-1α-induced regulation of lung injury in pulmonary aspiration is mediated through NF-kB. FASEB Bioadv. 2022;4:309-328 pubmed publisher |
| Vianello C, Cocetta V, Catanzaro D, Dorn G, De Milito A, Rizzolio F, et al. Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy. Cell Death Dis. 2022;13:398 pubmed publisher |
| Cristancho A, Gadra E, Samba I, Zhao C, Ouyang M, Magnitsky S, et al. Deficits in Seizure Threshold and Other Behaviors in Adult Mice without Gross Neuroanatomic Injury after Late Gestation Transient Prenatal Hypoxia. Dev Neurosci. 2022;44:246-265 pubmed publisher |
| Fuentes Fayos A, P xe9 rez G xf3 mez J, G Garc xed a M, Jim xe9 nez Vacas J, Blanco Acevedo C, S xe1 nchez S xe1 nchez R, et al. SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances. J Exp Clin Cancer Res. 2022;41:39 pubmed publisher |
| Clees A, Stolp V, Häupl B, Fuhrmann D, Wempe F, Seibert M, et al. Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene. Cells. 2022;11: pubmed publisher |
| Moberg M, Apr xf3 W, Horwath O, van Hall G, Blackwood S, Katz A. Acute normobaric hypoxia blunts contraction-mediated mTORC1- and JNK-signaling in human skeletal muscle. Acta Physiol (Oxf). 2022;234:e13771 pubmed publisher |
| Lefort S, El Naggar A, Tan S, Colborne S, Negri G, Pellacani D, et al. De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer. Cell Death Differ. 2021;: pubmed publisher |
| Li W, Duan A, Xing Y, Xu L, Yang J. Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules. Front Cell Dev Biol. 2021;9:690079 pubmed publisher |
| Siddiqui F, Vukic V, Salminen T, Abankwa D. Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity. Biomolecules. 2021;11: pubmed publisher |
| Wang R, Henen M, Lee J, V xf6 geli B, Colgan S. Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor. Gut Microbes. 2021;13:1938380 pubmed publisher |
| Lopez Ramirez M, Lai C, Soliman S, Hale P, Pham A, Estrada E, et al. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021;131: pubmed publisher |
| Siddiqui F, Parkkola H, Vukic V, Oetken Lindholm C, Jaiswal A, Kiriazis A, et al. Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling. Cancers (Basel). 2021;13: pubmed publisher |
| McCann K, Yadav M, Alishahedani M, Freeman A, Myles I. Differential responses to folic acid in an established keloid fibroblast cell line are mediated by JAK1/2 and STAT3. PLoS ONE. 2021;16:e0248011 pubmed publisher |
| Andrysik Z, Bender H, Galbraith M, Espinosa J. Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. Nat Commun. 2021;12:1375 pubmed publisher |
| Perrin Cocon L, Vidalain P, Jacquemin C, Aublin Gex A, Olmstead K, Panthu B, et al. A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity. Commun Biol. 2021;4:217 pubmed publisher |
| Schaff D, Singh S, Kim K, Sutcliffe M, Park K, Janes K. Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments. Cancer Res. 2021;: pubmed publisher |
| Honda T, Hirakawa Y, Mizukami K, Yoshihara T, Tanaka T, Tobita S, et al. A distinctive distribution of hypoxia-inducible factor-1α in cultured renal tubular cells with hypoperfusion simulated by coverslip placement. Physiol Rep. 2021;9:e14689 pubmed publisher |
| Cheng Y, Chiang H, Cheng S, Chang H, Li Y, Shieh S. Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation. Cell Death Dis. 2020;11:1046 pubmed publisher |
| Carrasco Pozo C, Tan K, Avery V. Hemin Prevents Increased Glycolysis in Macrophages upon Activation: Protection by Microbiota-Derived Metabolites of Polyphenols. Antioxidants (Basel). 2020;9: pubmed publisher |
| Turhan A, Pereira M, Schuler G, Bleul U, Kowalewski M. Hypoxia-inducible factor (HIF1alpha) inhibition modulates cumulus cell function and affects bovine oocyte maturation in vitro. Biol Reprod. 2020;: pubmed publisher |
| Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen M, et al. Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2. Sci Adv. 2020;6: pubmed publisher |
| Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher |
| Dowdell A, Cartwright I, Goldberg M, Kostelecky R, Ross T, Welch N, et al. The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis. Mol Biol Cell. 2020;31:2249-2258 pubmed publisher |
| Cohrs G, Drucks B, Synowitz M, Held Feindt J, Knerlich Lukoschus F. Expression Patterns of Hypoxia-Inducible Factors, Proinflammatory, and Neuroprotective Cytokines in Neuroepithelial Tissues of Lumbar Spinal Lipomas-A Pilot Study. World Neurosurg. 2020;141:e633-e644 pubmed publisher |
| James N, Emerson J, Borgstadt A, Beffa L, Oliver M, Hovanesian V, et al. The biomarker HE4 (WFDC2) promotes a pro-angiogenic and immunosuppressive tumor microenvironment via regulation of STAT3 target genes. Sci Rep. 2020;10:8558 pubmed publisher |
| Ménégaut L, Thomas C, Jalil A, Julla J, Magnani C, Ceroi A, et al. Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages. Cell Rep. 2020;31:107665 pubmed publisher |
| Peng W, de Bruijn H, ten Hagen T, van Dam G, Roodenburg J, Berg K, et al. Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model. Photochem Photobiol. 2020;96:708-717 pubmed publisher |
| Liu L, Zhang L, Zhao J, Guo X, Luo Y, Hu W, et al. Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes. Oxid Med Cell Longev. 2020;2020:6431517 pubmed publisher |
| Okada K, Mori D, Makii Y, Nakamoto H, Murahashi Y, Yano F, et al. Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling. Sci Rep. 2020;10:5425 pubmed publisher |
| Lucia K, Wu Y, Garcia J, Barlier A, Buchfelder M, Saeger W, et al. Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription. Oncogene. 2020;39:3367-3380 pubmed publisher |
| Sorkin M, Huber A, HWANG C, Carson W, Menon R, Li J, et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020;11:722 pubmed publisher |
| Wierenga A, Cunningham A, Erdem A, Lopera N, Brouwers Vos A, Pruis M, et al. HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells. Cancer Metab. 2019;7:11 pubmed publisher |
| Andrade F, Nguyen N, Warri A, Hilakivi Clarke L. Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy. Sci Rep. 2019;9:20271 pubmed publisher |
| Chao A, Chen C, Wu M, Hou B, Yang D. Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron. Biochim Biophys Acta Mol Cell Res. 2020;1867:118628 pubmed publisher |
| Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, et al. Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis. Biomed Pharmacother. 2020;123:109783 pubmed publisher |
| Han H, Jain A, Truica M, Izquierdo Ferrer J, Anker J, Lysy B, et al. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019;36:483-497.e15 pubmed publisher |
| Carrasco Pozo C, Tan K, Rodriguez T, Avery V. The Molecular Effects of Sulforaphane and Capsaicin on Metabolism upon Androgen and Tip60 Activation of Androgen Receptor. Int J Mol Sci. 2019;20: pubmed publisher |
| Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, et al. Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. Cell Rep. 2019;29:89-103.e7 pubmed publisher |
| Zhao L, Liu Z, Yang F, Zhang Y, Xue Y, Miao H, et al. Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α. Sci Rep. 2019;9:11861 pubmed publisher |
| Oyama Y, Bartman C, Bonney S, Lee J, Walker L, Han J, et al. Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Rep. 2019;28:1471-1484.e11 pubmed publisher |
| Mallikarjuna P, Raviprakash T, Aripaka K, Ljungberg B, Landström M. Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma. Cell Cycle. 2019;18:2141-2156 pubmed publisher |
| Masterson J, Biette K, Hammer J, Nguyen N, Capocelli K, Saeedi B, et al. Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis. J Clin Invest. 2019;129:3224-3235 pubmed publisher |
| Abe H, Takeda N, Isagawa T, Semba H, Nishimura S, Morioka M, et al. Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M. Nat Commun. 2019;10:2824 pubmed publisher |
| Locri F, Dal Monte M, Aronsson M, Cammalleri M, De Rosa M, Pavone V, et al. UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis. J Mol Med (Berl). 2019;97:1273-1283 pubmed publisher |
| Kaushik D, Bhattacharya A, Mirzaei R, Rawji K, Ahn Y, Rho J, et al. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019;129:3277-3292 pubmed publisher |
| Yang Y, Li M, Xu G, Feng L, Zhang E, Chen J, et al. Nogo-B Receptor Directs Mitochondria-Associated Membranes to Regulate Vascular Smooth Muscle Cell Proliferation. Int J Mol Sci. 2019;20: pubmed publisher |
| Tumova S, Kerimi A, Williamson G. Long term treatment with quercetin in contrast to the sulfate and glucuronide conjugates affects HIF1α stability and Nrf2 signaling in endothelial cells and leads to changes in glucose metabolism. Free Radic Biol Med. 2019;137:158-168 pubmed publisher |
| Harms M, Li Q, Lee S, Zhang C, Kull B, Hallen S, et al. Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes. Cell Rep. 2019;27:213-225.e5 pubmed publisher |
| Fu H, Ding X, Zhang W, Kang Y. Profiling of nuclear copper-binding proteins under hypoxic condition. Biometals. 2019;32:329-341 pubmed publisher |
| Wu Z, Zhang W, Kang Y. Copper affects the binding of HIF-1α to the critical motifs of its target genes. Metallomics. 2019;11:429-438 pubmed publisher |
| Lambertini E, Penolazzi L, Angelozzi M, Bergamin L, Manferdini C, Vieceli Dalla Sega F, et al. Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation. Cell Physiol Biochem. 2018;51:2237-2249 pubmed publisher |
| Fuhrmann D, Wittig I, Brüne B. TMEM126B deficiency reduces mitochondrial SDH oxidation by LPS, attenuating HIF-1α stabilization and IL-1β expression. Redox Biol. 2019;20:204-216 pubmed publisher |
| Yang L, Chen M, Zhang J, Ren D, Hu B. Hypoxia Delays Oligodendrocyte Progenitor Cell Migration and Myelin Formation by Suppressing Bmp2b Signaling in Larval Zebrafish. Front Cell Neurosci. 2018;12:348 pubmed publisher |
| Cohrs G, Drucks B, Sürie J, Vokuhl C, Synowitz M, Held Feindt J, et al. Expression profiles of pro-inflammatory and pro-apoptotic mediators in secondary tethered cord syndrome after myelomeningocele repair surgery. Childs Nerv Syst. 2019;35:315-328 pubmed publisher |
| Stoyanoff T, Rodriguez J, Todaro J, Colavita J, Torres A, Aguirre M. Erythropoietin attenuates LPS-induced microvascular damage in a murine model of septic acute kidney injury. Biomed Pharmacother. 2018;107:1046-1055 pubmed publisher |
| Ronellenfitsch M, Zeiner P, Mittelbronn M, Urban H, Pietsch T, Reuter D, et al. Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma. Acta Neuropathol Commun. 2018;6:81 pubmed publisher |
| Zheng J, Zhang M, Weng H. Induction of the mitochondrial NDUFA4L2 protein by HIF-1a regulates heart regeneration by promoting the survival of cardiac stem cell. Biochem Biophys Res Commun. 2018;503:2226-2233 pubmed publisher |
| Peruzzotti Jametti L, Bernstock J, Vicario N, Costa A, Kwok C, Leonardi T, et al. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell. 2018;22:355-368.e13 pubmed publisher |
| Dopeso H, Jiao H, Cuesta A, Henze A, Jurida L, Kracht M, et al. PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα. Cancer Res. 2018;78:1805-1819 pubmed publisher |
| Eriksson J, Wanka C, Burger M, Urban H, Hartel I, von Renesse J, et al. Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma. J Neurochem. 2017;: pubmed publisher |
| McClendon J, Jansing N, Redente E, Gandjeva A, Ito Y, Colgan S, et al. Hypoxia-Inducible Factor 1? Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury. Am J Pathol. 2017;187:1772-1786 pubmed publisher |
| Li D, Du Y, Yuan X, Han X, Dong Z, Chen X, et al. Hepatic hypoxia-inducible factors inhibit PPAR? expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity. Free Radic Biol Med. 2017;110:102-116 pubmed publisher |
| Zhang X, Liu L, Liu J, Cheng Z, Wang Z, Shi C, et al. Endothelial cells co-cultured with renal carcinoma cells significantly reduce RECK expression under chemical hypoxia. Cell Biol Int. 2017;41:922-927 pubmed publisher |
| Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, et al. Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia. Physiol Rep. 2017;5: pubmed publisher |
| Hou F, Li W, Shi Q, Li H, Liu S, Zong S, et al. Yi Ai Fang, a traditional Chinese herbal formula, impacts the vasculogenic mimicry formation of human colorectal cancer through HIF-1? and epithelial mesenchymal transition. BMC Complement Altern Med. 2016;16:428 pubmed |
| Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, et al. 24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development. Proc Natl Acad Sci U S A. 2016;113:E6219-E6227 pubmed |
| Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, et al. Hypoxia-Inducible Factor-1? Activates the Transforming Growth Factor-?/SMAD3 Pathway in Kidney Tubular Epithelial Cells. Am J Nephrol. 2016;44:276-285 pubmed |
| Campillo N, Jorba I, Schaedel L, Casals B, Gozal D, Farre R, et al. A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea. Front Physiol. 2016;7:319 pubmed publisher |
| Sullivan A, Peet D, Whitelaw M. MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors. FEBS J. 2016;283:3488-502 pubmed publisher |
| Kowitzke B, Cohrs G, Leuschner I, Koch A, Synowitz M, Mehdorn H, et al. Cellular Profiles and Molecular Mediators of Lesion Cascades in the Placode in Human Open Spinal Neural Tube Defects. J Neuropathol Exp Neurol. 2016;75:827-42 pubmed publisher |
| Hoang N, Kadonosono T, Kuchimaru T, Kizaka Kondoh S. Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model. Cancer Sci. 2016;107:1151-8 pubmed publisher |
| Mammadzada P, Gudmundsson J, Kvanta A, André H. Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis. Acta Ophthalmol. 2016;94:805-814 pubmed publisher |
| Jang J, Ko M, Yun J, Kim M, Kim J, Park H, et al. Nitric Oxide Produced by Macrophages Inhibits Adipocyte Differentiation and Promotes Profibrogenic Responses in Preadipocytes to Induce Adipose Tissue Fibrosis. Diabetes. 2016;65:2516-28 pubmed publisher |
| Takahashi N, Davy P, Gardner L, Mathews J, Yamazaki Y, Allsopp R. Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle. PLoS ONE. 2016;11:e0154309 pubmed publisher |
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| Song M, Liu T, Shi C, Zhang X, Chen X. Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia. ACS Nano. 2016;10:633-647 pubmed publisher |
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