AIP/ARA9 Antibody (35-2) | Novus Biologicals NB100-127 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

AIP/ARA9 Antibody (35-2)

catalog :

NB100-127

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

35-2

reactivity :

primate, human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 35

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 3c	Chen J, Haller C, Jernigan F, Koerner S, Wong D, Wang Y, et al. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv. 2020;6:eaay8230 pubmed publisher
immunohistochemistry; human; 1:1600; loading ...; fig 2f	De Sousa S, Manavis J, Feng J, Wang P, Schreiber A, Scott H, et al. A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease. BMC Endocr Disord. 2020;20:18 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 3a	Ozkaya H, Comunoglu N, Sayitoglu M, Keskin F, Firtina S, Khodzhaev K, et al. Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues. Pituitary. 2018;21:335-346 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500; fig 2	Rotondi S, Modarelli A, Oliva M, Rostomyan L, Sanità P, Ventura L, et al. Expression of Peroxisome Proliferator-Activated Receptor alpha (PPARÎ±) in somatotropinomas: Relationship with Aryl hydrocarbon receptor Interacting Protein (AIP) and in vitro effects of fenofibrate in GH3 cells. Mol Cell Endocrinol. 2016;426:61-72 pubmed publisher
immunohistochemistry - paraffin section; human	Beckers A, Lodish M, Trivellin G, Rostomyan L, Lee M, Faucz F, et al. X-linked acrogigantism syndrome: clinical profile and therapeutic responses. Endocr Relat Cancer. 2015;22:353-67 pubmed publisher
immunohistochemistry - paraffin section; human western blot; human immunohistochemistry - paraffin section; rat western blot; rat	DÃ©nes J, Kasuki L, Trivellin G, Colli L, Takiya C, Stiles C, et al. Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas. PLoS ONE. 2015;10:e0117107 pubmed publisher
immunohistochemistry - paraffin section; human	Mian C, Ceccato F, Barollo S, Watutantrige Fernando S, Albiger N, Regazzo D, et al. AHR over-expression in papillary thyroid carcinoma: clinical and molecular assessments in a series of Italian acromegalic patients with a long-term follow-up. PLoS ONE. 2014;9:e101560 pubmed publisher
immunohistochemistry; human	Jaffrain Rea M, Rotondi S, Turchi A, Occhi G, Barlier A, Peverelli E, et al. Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations. Endocr Relat Cancer. 2013;20:753-66 pubmed publisher
immunocytochemistry; rat western blot; rat	Formosa R, Xuereb Anastasi A, Vassallo J. Aip regulates cAMP signalling and GH secretion in GH3 cells. Endocr Relat Cancer. 2013;20:495-505 pubmed publisher
western blot; human	Kasai S, Ishigaki T, Takumi R, Kamimura T, Kikuchi H. Beta-catenin signaling induces CYP1A1 expression by disrupting adherens junctions in Caco-2 human colon carcinoma cells. Biochim Biophys Acta. 2013;1830:2509-16 pubmed
western blot; human western blot; rat	Trivellin G, Butz H, Delhove J, Igreja S, Chahal H, Zivkovic V, et al. MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro. Am J Physiol Endocrinol Metab. 2012;303:E708-19 pubmed publisher
immunohistochemistry; rat western blot; rat immunohistochemistry; human western blot; human	Chahal H, Trivellin G, Leontiou C, Alband N, Fowkes R, Tahir A, et al. Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway. J Clin Endocrinol Metab. 2012;97:E1411-20 pubmed publisher
chromatin immunoprecipitation; human immunoprecipitation; human western blot; human	Cai W, Kramarova T, Berg P, Korbonits M, Pongratz I. The immunophilin-like protein XAP2 is a negative regulator of estrogen signaling through interaction with estrogen receptor ?. PLoS ONE. 2011;6:e25201 pubmed publisher
western blot; mouse	Kang B, Xia F, Pop R, Dohi T, Socolovsky M, Altieri D. Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein. J Biol Chem. 2011;286:16758-67 pubmed publisher
western blot; human	Schülke J, Wochnik G, Lang Rollin I, Gassen N, Knapp R, Berning B, et al. Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors. PLoS ONE. 2010;5:e11717 pubmed publisher
immunohistochemistry - paraffin section; human immunohistochemistry; human	Toledo R, Mendonca B, Fragoso M, Soares I, Almeida M, Moraes M, et al. Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis. Clinics (Sao Paulo). 2010;65:407-15 pubmed publisher
western blot; human western blot; mouse western blot; rat	Heliövaara E, Raitila A, Launonen V, Paetau A, Arola J, Lehtonen H, et al. The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas. Am J Pathol. 2009;175:2501-7 pubmed publisher
immunohistochemistry - paraffin section; human immunohistochemistry; human	Jaffrain Rea M, Angelini M, Gargano D, Tichomirowa M, Daly A, Vanbellinghen J, et al. Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications. Endocr Relat Cancer. 2009;16:1029-43 pubmed publisher
western blot; mouse	Pollenz R, Wilson S, Dougherty E. Role of endogenous XAP2 protein on the localization and nucleocytoplasmic shuttling of the endogenous mouse Ahb-1 receptor in the presence and absence of ligand. Mol Pharmacol. 2006;70:1369-79 pubmed
immunoprecipitation; primate western blot; primate	Petrulis J, Hord N, Perdew G. Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2. J Biol Chem. 2000;275:37448-53 pubmed
	Lee H, Jung Y, Choi G, Kim J, Chae C, Lim J, et al. Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis. Cell Death Differ. 2020;: pubmed publisher
	Hage C, Sabini E, Alsharhan H, Fahrner J, Beckers A, Daly A, et al. Acromegaly in the setting of Tatton-Brown-Rahman Syndrome. Pituitary. 2020;23:167-170 pubmed publisher
	Sun D, Stopka Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkamper A, et al. Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation. Cell Rep. 2019;27:1461-1471.e4 pubmed publisher
	Daly A, Cano D, Venegas Moreno E, Petrossians P, Dios E, Castermans E, et al. AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. Endocr Connect. 2019;8:338-348 pubmed publisher
	Yamamoto R, Robert Shima K, Igawa H, Kaikoi Y, Sasagawa Y, Hayashi Y, et al. Impact of preoperative pasireotide therapy on invasive octreotide-resistant acromegaly. Endocr J. 2018;65:1061-1067 pubmed publisher
	HernÃ¡ndez RamÃrez L, Morgan R, Barry S, D Acquisto F, Prodromou C, Korbonits M. Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland. Oncotarget. 2018;9:9177-9198 pubmed publisher
	Kasuki L, Wildemberg L, Gadelha M. MANAGEMENT OF ENDOCRINE DISEASE: Personalized medicine in the treatment of acromegaly. Eur J Endocrinol. 2018;178:R89-R100 pubmed publisher
	De Sousa S, McCabe M, Wu K, Roscioli T, Gayevskiy V, Brook K, et al. Germline variants in familial pituitary tumour syndrome genes are common in young patients and families with additional endocrine tumours. Eur J Endocrinol. 2017;176:635-644 pubmed publisher
	Ritvonen E, Pitkänen E, Karppinen A, Vehkavaara S, Demir H, Paetau A, et al. Impact of AIP and inhibitory G protein alpha 2 proteins on clinical features of sporadic GH-secreting pituitary adenomas. Eur J Endocrinol. 2017;176:243-252 pubmed publisher
	Fukuda T, Tanaka T, Hamaguchi Y, Kawanami T, Nomiyama T, Yanase T. Augmented Growth Hormone Secretion and Stat3 Phosphorylation in an Aryl Hydrocarbon Receptor Interacting Protein (AIP)-Disrupted Somatotroph Cell Line. PLoS ONE. 2016;11:e0164131 pubmed publisher
	Iacovazzo D, Carlsen E, Lugli F, Chiloiro S, Piacentini S, Bianchi A, et al. Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study. Eur J Endocrinol. 2016;174:241-50 pubmed publisher
	Kasuki L, Neto L, Takiya C, Gadelha M. Growth of an aggressive tumor during pregnancy in an acromegalic patient. Endocr J. 2012;59:313-9 pubmed
	Kasuki Jomori de Pinho L, Vieira Neto L, Armondi Wildemberg L, Gasparetto E, Marcondes J, de Almeida Nunes B, et al. Low aryl hydrocarbon receptor-interacting protein expression is a better marker of invasiveness in somatotropinomas than Ki-67 and p53. Neuroendocrinology. 2011;94:39-48 pubmed publisher
	Sethi N, Yan Y, Quek D, Schupbach T, Kang Y. Rabconnectin-3 is a functional regulator of mammalian Notch signaling. J Biol Chem. 2010;285:34757-64 pubmed publisher
	Hollingshead B, Petrulis J, Perdew G. The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function. J Biol Chem. 2004;279:45652-61 pubmed

product information

master code :

NB100-127

SKU :

NB100-127

product name :

AIP/ARA9 Antibody (35-2)

unit size :

0.1 ml (also 0.025 ml)

description :

The AIP/ARA9 Antibody (35-2) - BSA Free from Novus is a mouse monoclonal antibody to AIP/ARA9. This antibody reacts with human,mouse,primate,rat. The AIP/ARA9 Antibody (35-2) - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry,Chemotaxis,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Simple Western,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing.

target :

AIP/ARA9

category :

Primary Antibodies

buffer :

Tissue culture supernatant

clonality :

Monoclonal

clone :

35-2

conjugate :

Unconjugated

host :

Mouse

immunogen :

Bacterially expressed human AIP/ARA9 [UniProt# O00170]

isotype :

IgG1

purity :

Tissue culture supernatant

species :

Human,Mouse,Primate,Rat

theoretical molecular weight :

37 kDa

gene symbol :

AIP

Antibody validation :

Biological Validation

accessionNumbers :

O00170

applications :

Immunohistochemistry,Western Blot,Chemotaxis,IF/IHC,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Simple Western,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing

USD :

409 USD

alt names :

ARA9, FKBP16, FKBP37, SMTPHN, XAP2, XAP-2

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage