product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNA Ligase I Antibody (10H5) - Azide and BSA Free
catalog :
NB100-119
quantity :
100 ul
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10H5
reactivity :
human, mouse, chicken
application :
western blot, immunocytochemistry, immunoprecipitation, radioimmunoassay, immunohistochemistry - paraffin section
more info or order :
citations: 24
Reference |
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Song W, Levin D, Varkey J, Post S, Bermudez V, Hurwitz J, et al. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007;282:22721-30 pubmed
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Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007;213:475-83 pubmed
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Rose J, Reeves K, Likhotvorik R, Hoyt D. Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. J Pharmacol Exp Ther. 2007;321:318-26 pubmed
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Wang W, Lindsey Boltz L, Sancar A, Bambara R. Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. J Biol Chem. 2006;281:20865-72 pubmed
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Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
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Warren M, Lord C, Masabanda J, Griffin D, Ashworth A. Phenotypic effects of heterozygosity for a BRCA2 mutation. Hum Mol Genet. 2003;12:2645-56 pubmed
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Kao G, McKenna W, Guenther M, Muschel R, Lazar M, Yen T. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol. 2003;160:1017-27 pubmed
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Tarsounas M, Davies D, West S. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene. 2003;22:1115-23 pubmed
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Masson J, Tarsounas M, Stasiak A, Stasiak A, Shah R, McIlwraith M, et al. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev. 2001;15:3296-307 pubmed
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Masson J, Davies A, Hajibagheri N, Van Dyck E, Benson F, Stasiak A, et al. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. EMBO J. 1999;18:6552-60 pubmed
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product information
master code :
NB100-119
SKU :
NB100-119
product name :
DNA Ligase I Antibody (10H5) - Azide and BSA Free
unit size :
100 ul
description :
The DNA Ligase I Antibody (10H5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to DNA Ligase I. This antibody reacts with avian - chicken,bacteria,fish,hamster,human,mouse,rabbit. The DNA Ligase I Antibody (10H5) - Azide and BSA Free has been validated for the following applications: Bacteria,Immunoprecipitation,Western Blot,Mass Spectrometry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,In vitro assay,Radioimmunoassay.
target :
DNA Ligase I
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
10H5
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full-length recombinant human DNA Ligase I protein
isotype :
IgG1
purity :
Protein G purified
species :
Avian - Chicken,Bacteria,Fish,Hamster,Human,Mouse,Rabbit
specificity :
This is specific for DNA ligase 1
theoretical molecular weight :
125 kDa
gene symbol :
LIG1
applications :
Bacteria,Immunoprecipitation,Western Blot,Mass Spectrometry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,In vitro assay,Radioimmunoassay
USD :
449 USD
alt names :
DNA ligase 1, DNA ligase I, EC 6.5.1.1, ligase I, DNA, ATP-dependent, MGC117397, MGC130025, Polydeoxyribonucleotide synthase [ATP] 1, polydeoxyribonucleotide synthase ATP 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information

Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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