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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNA Ligase I Antibody (10H5) - Azide and BSA Free
catalog :
NB100-119
quantity :
100 ul
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10H5
reactivity :
human, mouse, chicken
application :
western blot, immunocytochemistry, immunoprecipitation, radioimmunoassay, immunohistochemistry - paraffin section
more info or order :
citations: 24
Reference
Velez C, Williamson D, C xe1 novas M, Giai L, Rutland C, P xe9 rez W, et al. Changes in Immune Response during Pig Gestation with a Focus on Cytokines. Vet Sci. 2024;11: pubmed publisher
Xu Y, Zhu Y, Bawa F, Hu S, Pan X, Yin L, et al. Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice. Hepatol Commun. 2020;4:527-539 pubmed publisher
Biswas L, Zeng Z, Graham A, Shu X. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells. Exp Eye Res. 2020;191:107931 pubmed publisher
Konopko A, Kusio J, Litwinienko G. Antioxidant Activity of Metal Nanoparticles Coated with Tocopherol-Like Residues-The Importance of Studies in Homo- and Heterogeneous Systems. Antioxidants (Basel). 2019;9: pubmed publisher
Sharma B, Gupta V, Dahiya D, Kumar H, Vaiphei K, Agnihotri N. Clinical relevance of cholesterol homeostasis genes in colorectal cancer. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:1314-1327 pubmed publisher
Xu J, Xu Y, Xu Y, Yin L, Zhang Y. Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr -/- mice. Sci Rep. 2017;7:17845 pubmed publisher
Yang Y, Yang Q, Yang J, Ma Y, Ding G. Angiotensin II induces cholesterol accumulation and injury in podocytes. Sci Rep. 2017;7:10672 pubmed publisher
Wang M, Gao M, Liao J, Qi Y, Du X, Wang Y, et al. Adipose tissue deficiency results in severe hyperlipidemia and atherosclerosis in the low-density lipoprotein receptor knockout mice. Biochim Biophys Acta. 2016;1861:410-8 pubmed publisher
Eckert E, Fontaneto D, Coci M, Callieri C. Does a barcoding gap exist in prokaryotes? Evidences from species delimitation in cyanobacteria. Life (Basel). 2014;5:50-64 pubmed publisher
Miles S, Matsuki K, Minda J. Continuous executive function disruption interferes with application of an information integration categorization strategy. Atten Percept Psychophys. 2014;76:1318-34 pubmed publisher
Jaiswal A, Narayan S. Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity. Biochemistry. 2011;50:1901-9 pubmed publisher
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton J, et al. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010;9:109-19 pubmed publisher
Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Nucleic Acids Res. 2009;37:3431-41 pubmed publisher
Song W, Levin D, Varkey J, Post S, Bermudez V, Hurwitz J, et al. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007;282:22721-30 pubmed
Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007;213:475-83 pubmed
Rose J, Reeves K, Likhotvorik R, Hoyt D. Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. J Pharmacol Exp Ther. 2007;321:318-26 pubmed
Wang W, Lindsey Boltz L, Sancar A, Bambara R. Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. J Biol Chem. 2006;281:20865-72 pubmed
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
Warren M, Lord C, Masabanda J, Griffin D, Ashworth A. Phenotypic effects of heterozygosity for a BRCA2 mutation. Hum Mol Genet. 2003;12:2645-56 pubmed
Kao G, McKenna W, Guenther M, Muschel R, Lazar M, Yen T. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol. 2003;160:1017-27 pubmed
Tarsounas M, Davies D, West S. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene. 2003;22:1115-23 pubmed
French C, Masson J, Griffin C, O Regan P, West S, Thacker J. Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability. J Biol Chem. 2002;277:19322-30 pubmed publisher
Masson J, Tarsounas M, Stasiak A, Stasiak A, Shah R, McIlwraith M, et al. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev. 2001;15:3296-307 pubmed
Masson J, Davies A, Hajibagheri N, Van Dyck E, Benson F, Stasiak A, et al. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. EMBO J. 1999;18:6552-60 pubmed
product information
master code :
NB100-119
SKU :
NB100-119
product name :
DNA Ligase I Antibody (10H5) - Azide and BSA Free
unit size :
100 ul
description :
The DNA Ligase I Antibody (10H5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to DNA Ligase I. This antibody reacts with avian - chicken,bacteria,fish,hamster,human,mouse,rabbit. The DNA Ligase I Antibody (10H5) - Azide and BSA Free has been validated for the following applications: Bacteria,Immunoprecipitation,Western Blot,Mass Spectrometry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,In vitro assay,Radioimmunoassay.
target :
DNA Ligase I
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
10H5
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full-length recombinant human DNA Ligase I protein
isotype :
IgG1
purity :
Protein G purified
species :
Avian - Chicken,Bacteria,Fish,Hamster,Human,Mouse,Rabbit
specificity :
This is specific for DNA ligase 1
theoretical molecular weight :
125 kDa
gene symbol :
LIG1
applications :
Bacteria,Immunoprecipitation,Western Blot,Mass Spectrometry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,In vitro assay,Radioimmunoassay
USD :
449 USD
alt names :
DNA ligase 1, DNA ligase I, EC 6.5.1.1, ligase I, DNA, ATP-dependent, MGC117397, MGC130025, Polydeoxyribonucleotide synthase [ATP] 1, polydeoxyribonucleotide synthase ATP 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.