This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) - BSA Free
catalog :
NB100-115
quantity :
0.1 mg (also 0.025 mg)
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3C5.1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Chui G, Linn S. Further characterization of HeLa DNA polymerase epsilon. J Biol Chem. 1995;270:7799-808 pubmed
Gaspar J, Mendes N, Correa da Silva F, Lima Junior J, Gaspar R, Ropelle E, et al. Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity. Brain Behav Immun. 2018;73:550-561 pubmed publisher
Asahara H, Li Y, Fuss J, Haines D, Vlatkovic N, Boyd M, et al. Stimulation of human DNA polymerase epsilon by MDM2. Nucleic Acids Res. 2003;31:2451-9 pubmed
Liu W, Linn S. Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. Nucleic Acids Res. 2000;28:4180-8 pubmed
Vlatkovic N, Guerrera S, Li Y, Linn S, Haines D, Boyd M. MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon. Nucleic Acids Res. 2000;28:3581-6 pubmed
Li Y, Pursell Z, Linn S. Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem. 2000;275:23247-52 pubmed
Kramata P, Downey K, Paborsky L. Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro. J Biol Chem. 1998;273:21966-71 pubmed
Islas L, Fairley C, Morgan W. DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination. Nucleic Acids Res. 1998;26:3729-38 pubmed
Li Y, Asahara H, Patel V, Zhou S, Linn S. Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon. J Biol Chem. 1997;272:32337-44 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB100-115
SKU :
NB100-115
product name :
DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) - BSA Free
Description :
The DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) - BSA Free from Novus is a mouse monoclonal antibody to DNA Polymerase epsilon catalytic subunit A. This antibody reacts with human, mouse, mustelid, primate, drosophila (negative). The DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) - BSA Free has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin.
target :
DNA Polymerase epsilon catalytic subunit A
category :
Primary Antibodies
unit size :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
3C5.1
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human DNA Polymerase epsilon purified from HeLa cells.
isotype :
IgG2a
purity :
Immunogen affinity purified
species :
Human, Mouse, Mustelid, Primate, Drosophila (Negative)
specificity :
This is specific to the human DNA pol epsilon and does not recognize DNA pol alpha, beta or delta
theoretical molecular weight :
220 kDa
gene symbol :
POLE
applications :
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
DKFZp434F222, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, EC 2.7.7, EC 2.7.7.7, POLE1FLJ21434, polymerase (DNA directed), epsilon
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.