product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal NTH1 Antibody
catalog :
NB100-108B
quantity :
0.2 ml
price :
469.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB100-108B
Product Name :
Rabbit Polyclonal NTH1 Antibody
List Price :
469.00 USD
Product Type :
Primary Antibodies
Package Size :
0.2 ml
AltNames :
EC 4.2.99.18, endonuclease III-like protein 1, nth endonuclease III-like 1 (E. coli), OCTS3NTH1nth (E.coli endonuclease III)-like 1
Background :
Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites. A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.
Buffer :
PBS
Clonality :
Polyclonal
Conjugate :
Biotin
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A peptide derived from human NTH1, conjugated to KLH. [UniProt# P78549]
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human, mouse and rat. Immunogen sequence has 93% identity with bovine proteins.
Storage :
Store at 4C in the dark.
Swissprot Human :
P78549
TMW :
37 kDa
Uses :
This NTH1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western Blot, where a single band is detected at 37 kDa representing NTH1.
Research Area :
Base Excision Repair, Cancer, Chromatin Research, Core ESC Like Genes, DNA Repair, Stem Cell Markers
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.