product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
OGG1 Antibody - BSA Free
catalog :
NB100-106
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
more info or order :
citations: 51
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4a
Wang S, Lai K, Li C, Chiang C, Yu G, Sakamoto N, et al. The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities. PLoS ONE. 2017;12:e0164281 pubmed publisher
Pan L, Wang K, Hao W, Xue Y, Zheng X, Basu R, et al. 8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus. PLoS Pathog. 2024;20:e1012616 pubmed publisher
Debsharma S, Pramanik S, Bindu S, Mazumder S, Das T, Pal U, et al. NSAID targets SIRT3 to trigger mitochondrial dysfunction and gastric cancer cell death. iScience. 2024;27:109384 pubmed publisher
Gao S, Chen L, Lin Z, Xu Z, Wang Y, Ling H, et al. 8-Oxoguanine DNA glycosylase protects cells from senescence via the p53-p21 pathway. Acta Biochim Biophys Sin (Shanghai). 2024;56:184-198 pubmed publisher
Song C, Xu Z, Liang Q, Mu Y, Liu M, Wu Z, et al. OGG1 promoted lung fibrosis by activating fibroblasts via interacting with Snail1. Int Immunopharmacol. 2024;126:111148 pubmed publisher
Kim H, Yang J, Herath K, Jeon Y, Son Y, Kwon D, et al. Oral Administration of Sargassum horneri Suppresses Particulate Matter-Induced Oxidative DNA Damage in Alveolar Macrophages of Allergic Airway Inflammation: Relevance to PM-Mediated M1/M2 AM Polarization. Mol Nutr Food Res. 2023;67:e2300462 pubmed publisher
Xue Y, Li C, Deng S, Chen X, Han J, Zheng X, et al. 8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276. J Biol Chem. 2023;299:105308 pubmed publisher
Focken J, Scheurer J, J xe4 ger A, Sch xfc rch C, K xe4 mereit S, Riel S, et al. Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes. Cell Rep. 2023;42:113148 pubmed publisher
Murakami A, Takeda D, Hirota J, Saito I, Amano Iga R, Yatagai N, et al. Relationship of Mitochondrial-Related Protein Expression with the Differentiation, Metastasis, and Poor Prognosis of Oral Squamous Cell Carcinoma. Cancers (Basel). 2023;15: pubmed publisher
Zhao F, Zhu J, Zhang M, Luo Y, Li Y, Shi L, et al. OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy. Cell Prolif. 2023;:e13418 pubmed publisher
Latino D, Chieffi Baccari G, Di Fiore M, Cioffi F, Venditti M, Giacco A, et al. Autophagy and mitochondrial damage in the testis of high-fat diet fed rats. Gen Comp Endocrinol. 2022;328:114104 pubmed publisher
Xu X, Qiao D, Pan L, Boldogh I, Zhao Y, Brasier A. RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection. Cells. 2022;11: pubmed publisher
Zheng X, Wang K, Pan L, Hao W, Xue Y, Bacsi A, et al. Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions. J Innate Immun. 2022;14:593-614 pubmed publisher
Szulc M, Kujawski R, Baraniak J, Kania Dobrowolska M, Kami x144 ska E, Gryszczy x144 ska A, et al. Differential Influence of Pueraria lobata Root Extract and Its Main Isoflavones on Ghrelin Levels in Alcohol-Treated Rats. Pharmaceuticals (Basel). 2021;15: pubmed publisher
Suliman H, Ma Q, Zhang Z, Ren J, Morris B, Crowley S, et al. Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury. Front Physiol. 2021;12:683098 pubmed publisher
Jung J, Nam J, Ryu K, Son I, Shin J, Baek W, et al. Salivary Immunoglobulin Gamma-3 Chain C Is a Promising Noninvasive Biomarker for Systemic Lupus Erythematosus. Int J Mol Sci. 2021;22: pubmed publisher
van der Slikke E, Star B, van Meurs M, Henning R, Moser J, Bouma H. Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI. Crit Care. 2021;25:36 pubmed publisher
Vitry G, Paulin R, Grobs Y, Lampron M, Shimauchi T, Lemay S, et al. Oxidized DNA Precursors Cleanup by NUDT1 Contributes to Vascular Remodeling in PAH. Am J Respir Crit Care Med. 2020;: pubmed publisher
Yang L, Liu G, Li X, Xia Z, Wang Y, Lin W, et al. Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis. Cell Death Dis. 2020;11:827 pubmed publisher
Yang L, Liu G, Fu L, Zhong W, Li X, Pan Q. DNA repair enzyme OGG1 promotes alveolar progenitor cell renewal and relieves PM2.5-induced lung injury and fibrosis. Ecotoxicol Environ Saf. 2020;205:111283 pubmed publisher
Pan G, Deshpande M, Pang H, Stemmer P, Carruthers N, Shearn C, et al. 4-Hydroxy-2-nonenal attenuates 8-oxoguanine DNA glycosylase 1 activity. J Cell Biochem. 2020;: pubmed publisher
Xie X, Chen Y, Liu J, Zhang W, Zhang X, Zha L, et al. High glucose induced endothelial cell reactive oxygen species via OGG1/PKC/NADPH oxidase pathway. Life Sci. 2020;256:117886 pubmed publisher
Pao P, Patnaik D, Watson L, Gao F, Pan L, Wang J, et al. HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. Nat Commun. 2020;11:2484 pubmed publisher
Kim S, Cheresh P, Jablonski R, Rachek L, Yeldandi A, Piseaux Aillon R, et al. Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis. Am J Physiol Lung Cell Mol Physiol. 2020;318:L1084-L1096 pubmed publisher
Sabnam S, Rizwan H, Pal S, Pal A. CEES-induced ROS accumulation regulates mitochondrial complications and inflammatory response in keratinocytes. Chem Biol Interact. 2020;321:109031 pubmed publisher
Zheng J, Akbari M, Schirmer C, Reynaert M, Loyens A, Lefebvre B, et al. Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy. Acta Neuropathol Commun. 2020;8:25 pubmed publisher
Hu M, Lou Y, Liu S, Mao Y, Le F, Wang L, et al. Altered expression of DNA damage repair genes in the brain tissue of mice conceived by in vitro fertilization. Mol Hum Reprod. 2020;26:141-153 pubmed publisher
Rizwan H, Pal S, Sabnam S, Pal A. High glucose augments ROS generation regulates mitochondrial dysfunction and apoptosis via stress signalling cascades in keratinocytes. Life Sci. 2020;241:117148 pubmed publisher
Zhan Y, Raza M, Yuan L, Zhu M. Critical Role of Oxidatively Damaged DNA in Selective Noradrenergic Vulnerability. Neuroscience. 2019;422:184-201 pubmed publisher
Wang J, Nagy N, Masucci M. The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization. Oncogene. 2020;39:603-616 pubmed publisher
Fouquerel E, Barnes R, Uttam S, Watkins S, Bruchez M, Opresko P. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019;: pubmed publisher
Aiken C, Tarry Adkins J, Spiroski A, Nuzzo A, Ashmore T, Rolfo A, et al. Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats. FASEB J. 2019;33:7758-7766 pubmed publisher
Aiken C, Tarry Adkins J, Spiroski A, Nuzzo A, Ashmore T, Rolfo A, et al. Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats. J Physiol. 2019;597:2391-2401 pubmed publisher
Iida R, Ueki M, Yasuda T. Knockout of Mpv17-Like Protein (M-LPH) Gene in Human Hepatoma Cells Results in Impairment of mtDNA Integrity through Reduction of TFAM, OGG1, and LIG3 at the Protein Levels. Oxid Med Cell Longev. 2018;2018:6956414 pubmed publisher
Lorenzo Y, Haug Berg K, Ringvold A, Petrovski G, Moe M, Collins A, et al. Levels of oxidative DNA damage are low in ex vivo engineered human limbal epithelial tissue. Acta Ophthalmol. 2018;96:834-840 pubmed publisher
Kumagae Y, Hirahashi M, Takizawa K, Yamamoto H, Gushima M, Esaki M, et al. Overexpression of MTH1 and OGG1 proteins in ulcerative colitis-associated carcinogenesis. Oncol Lett. 2018;16:1765-1776 pubmed publisher
Kleme M, Sane A, Garofalo C, Seidman E, Brochiero E, Berthiaume Y, et al. CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells. Nutrients. 2018;10: pubmed publisher
Sarja H, Anttila T, Mustonen C, Honkanen H, Herajärvi J, Haapanen H, et al. Diazoxide Attenuates Ischemic Myocardial Injury in a Porcine Model. Heart Surg Forum. 2017;20:E153-E161 pubmed publisher
Rivera Barahona A, Alonso Barroso E, Perez B, Murphy M, Richard E, Desviat L. Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia. Mol Genet Metab. 2017;122:43-50 pubmed publisher
Pillai V, Kanwal A, Fang Y, Sharp W, Samant S, Arbiser J, et al. Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice. Oncotarget. 2017;8:34082-34098 pubmed publisher
Yang J, Chen W, Chen Y, Kuo C, Chen S. Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1. Theranostics. 2016;6:2015-2027 pubmed
Nikitaki Z, Nikolov V, Mavragani I, Mladenov E, Mangelis A, Laskaratou D, et al. Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET). Free Radic Res. 2016;50:S64-S78 pubmed
Tarry Adkins J, Fernandez Twinn D, Chen J, Hargreaves I, Neergheen V, Aiken C, et al. Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats. Dis Model Mech. 2016;9:1221-1229 pubmed
Martin L, Wong M. Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration. Mech Ageing Dev. 2017;161:149-162 pubmed publisher
Chaisiriwong L, Wanitphakdeedecha R, Sitthinamsuwan P, Sampattavanich S, Chatsiricharoenkul S, Manuskiatti W, et al. A Case-Control Study of Involvement of Oxidative DNA Damage and Alteration of Antioxidant Defense System in Patients with Basal Cell Carcinoma: Modulation by Tumor Removal. Oxid Med Cell Longev. 2016;2016:5934024 pubmed publisher
Moreli J, Santos J, Lorenzon Ojea A, Correa Silva S, Fortunato R, Rocha C, et al. Hyperglycemia Differentially Affects Maternal and Fetal DNA Integrity and DNA Damage Response. Int J Biol Sci. 2016;12:466-77 pubmed publisher
Kohno Y, Yamamoto H, Hirahashi M, Kumagae Y, Nakamura M, Oki E, et al. Reduced MUTYH, MTH1, and OGG1 expression and TP53 mutation in diffuse-type adenocarcinoma of gastric cardia. Hum Pathol. 2016;52:145-52 pubmed publisher
Leon J, Sakumi K, Castillo E, Sheng Z, Oka S, Nakabeppu Y. 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions. Sci Rep. 2016;6:22086 pubmed publisher
Liśkiewicz A, Kasprowska D, Wojakowska A, Polański K, Lewin Kowalik J, Kotulska K, et al. Long-term High Fat Ketogenic Diet Promotes Renal Tumor Growth in a Rat Model of Tuberous Sclerosis. Sci Rep. 2016;6:21807 pubmed publisher
Zijno A, de Angelis I, De Berardis B, Andreoli C, Russo M, Pietraforte D, et al. Different mechanisms are involved in oxidative DNA damage and genotoxicity induction by ZnO and TiO2 nanoparticles in human colon carcinoma cells. Toxicol In Vitro. 2015;29:1503-12 pubmed publisher
Fridlich R, Annamalai D, Roy R, Bernheim G, Powell S. BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-strand breaks during DNA replication. DNA Repair (Amst). 2015;30:11-20 pubmed publisher
product information
master code :
NB100-106
SKU :
NB100-106
product name :
OGG1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The OGG1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to OGG1. This antibody reacts with human,mouse,porcine,primate,rabbit,rat. The OGG1 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,Proximity Ligation Assay,Flow Cytometry,Flow (Intracellular).
target :
OGG1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A peptide derived from human Ogg1 (within amino acids 1-100). [UniProt# O15527]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Primate,Rabbit,Rat
theoretical molecular weight :
39 kDa
gene symbol :
OGG1
accessionNumbers :
O15527
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,Proximity Ligation Assay,Flow Cytometry,Flow (Intracellular)
USD :
469 USD
alt names :
8-hydroxyguanine DNA glycosylase, 8-oxoguanine DNA glycosylase, AP lyase, DNA-apurinic or apyrimidinic site lyase, HOGG1, MMH, MUTMOGH1HMMH, N-glycosylase/DNA lyase
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.