Dynein intermediate chain 2 Antibody (1C8) | Novus Biologicals H00064446-M01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Dynein intermediate chain 2 Antibody (1C8)

catalog :

H00064446-M01

quantity :

0.1 mg

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1C8

reactivity :

human, mouse, dogs

application :

western blot, ELISA, immunocytochemistry

citations: 12

Reference
Li Y, Sha Y, Wang X, Ding L, Liu W, Ji Z, et al. DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella. Clin Genet. 2019;95:590-600 pubmed publisher
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, et al. Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2019;11:383-394 pubmed publisher
Cho K, Noh S, Han S, Choi W, Kim H, Yu S, et al. ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms. PLoS Genet. 2018;14:e1007316 pubmed publisher
Miao C, Jiang Q, Li H, Zhang Q, Bai B, Bao Y, et al. Mutations in the Motile Cilia Gene DNAAF1 Are Associated with Neural Tube Defects in Humans. G3 (Bethesda). 2016;6:3307-3316 pubmed publisher
Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher
Diggle C, Moore D, Mali G, Zur Lage P, Ait Lounis A, Schmidts M, et al. HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. PLoS Genet. 2014;10:e1004577 pubmed publisher
Dong F, Shinohara K, Botilde Y, Nabeshima R, Asai Y, Fukumoto A, et al. Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014;204:203-13 pubmed publisher
Ben Khelifa M, Coutton C, Zouari R, Karaouzene T, Rendu J, Bidart M, et al. Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella. Am J Hum Genet. 2014;94:95-104 pubmed publisher
Tarkar A, Loges N, Slagle C, Francis R, Dougherty G, Tamayo J, et al. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013;45:995-1003 pubmed publisher
Astanina K, Jacob R. KIF5C, a kinesin motor involved in apical trafficking of MDCK cells. Cell Mol Life Sci. 2010;67:1331-42 pubmed publisher
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges N, Hagiwara H, et al. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008;456:611-6 pubmed publisher
Loges N, Olbrich H, Fenske L, Mussaffi H, Horvath J, Fliegauf M, et al. DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm. Am J Hum Genet. 2008;83:547-58 pubmed publisher

product information

brand :

Novus

master code :

H00064446-M01

SKU :

H00064446-M01

product name :

Dynein intermediate chain 2 Antibody (1C8)

description :

The Dynein intermediate chain 2 Antibody (1C8) from Novus Biologicals is a mouse monoclonal antibody to Dynein intermediate chain 2. This antibody reacts with human, mouse, canine, reptile. The Dynein intermediate chain 2 Antibody (1C8) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Functional, Sandwich ELISA.

target :

Dynein intermediate chain 2

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

1C8

conjugate :

Unconjugated

host :

Mouse

immunogen :

MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAE
QFVERNPVDTGIQCSISMSEHEANSERFEMETRGVNHVE
GGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIM
EHCIKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFR
DPQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMS
SDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLG
GCYNGQIACWDTRKGSLVAELSTIESSHRDPVYGTIWLQ
SKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKE
QLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKT
SAEKIVCTFPGHHGPIYALQRNPFYPKNFLTVGDWTARI
WSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMD
GTLDIWDFMFEQCDPTLSLKDNGCLIACGSQLGTTTLLE
VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRL
KEKGKAEGRDEEQTDEELAVDLEALVSKAEEEFFDIIFT
ELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGD
EEVEEDLA
DNAI2 (AAH39582, 1 a.a. ~ 593 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2a Kappa

purity :

IgG purified

species :

Human, Mouse, Canine, Reptile

specificity :

DNAI2 - dynein, axonemal, intermediate polypeptide 2

gene symbol :

DNAI2

catalog number base :

H00064446-M01

accessionNumbers :

AAH39582

applications :

Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Functional, Sandwich ELISA

2020 USD :

399

2021 USD :

399 USD

alt names :

Axonemal dynein intermediate chain 2, CILD9, dynein intermediate chain 2, axonemal, dynein, axonemal, intermediate chain 2, dynein, axonemal, intermediate polypeptide 2

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.