DDX41 Antibody (2F4) | Novus Biologicals H00051428-M01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DDX41 Antibody (2F4)

catalog :

H00051428-M01

quantity :

0.1 mg

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F4

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

citations: 5

Reference
Yoneyama Hirozane M, Kondo M, Matsumoto S, Morikawa Oki A, Morishita D, Nakanishi A, et al. High-Throughput Screening to Identify Inhibitors of DEAD Box Helicase DDX41. SLAS Discov. 2017;22:1084-1092 pubmed publisher
Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, et al. Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. Sci Rep. 2016;6:34756 pubmed publisher
Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, et al. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. J Immunol. 2015;194:1545-54 pubmed publisher
Parvatiyar K, Zhang Z, Teles R, Ouyang S, Jiang Y, Iyer S, et al. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol. 2012;13:1155-61 pubmed publisher
Zhang Z, Yuan B, Bao M, Lu N, Kim T, Liu Y. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat Immunol. 2011;12:959-65 pubmed publisher

product information

brand :

Novus

master code :

H00051428-M01

SKU :

H00051428-M01

product name :

DDX41 Antibody (2F4)

description :

The DDX41 Antibody (2F4) from Novus Biologicals is a mouse monoclonal antibody to DDX41. This antibody reacts with human, mouse. The DDX41 Antibody (2F4) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Sandwich ELISA.

target :

DDX41

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

2F4

conjugate :

Unconjugated

host :

Mouse

immunogen :

TGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPP
VLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEA
MQTKQVSNIGRKDYLAHSSMDF
DDX41 (NP_057306, 523 a.a. ~ 622 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG1 Kappa

purity :

IgG purified

species :

Human, Mouse

specificity :

DDX41 - DEAD (Asp-Glu-Ala-Asp) box polypeptide 41

gene symbol :

DDX41

catalog number base :

H00051428-M01

accessionNumbers :

NP_057306

applications :

Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Sandwich ELISA

2020 USD :

399

2021 USD :

399 USD

alt names :

ABSDEAD-box protein abstrakt, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41, DEAD box protein 41, DEAD box protein abstrakt homolog, EC 3.6.1, EC 3.6.4.13,2900024F02Rik, MGC8828, probable ATP-dependent RNA helicase DDX41, putative RNA helicase

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.