LASS2 Antibody (1A6) | Novus Biologicals H00029956-M01A product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

LASS2 Antibody (1A6)

catalog :

H00029956-M01A

quantity :

0.2 ml

price :

529 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A6

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Mart xed n Leal A, Blanco R, Casas J, S xe1 ez M, Rodr xed guez Bovolenta E, de Rojas I, et al. CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesis. EMBO J. 2020;39:e104749 pubmed publisher
Couttas T, Kain N, Suchowerska A, Quek L, Turner N, Fath T, et al. Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease. Neurobiol Aging. 2016;43:89-100 pubmed publisher
Novgorodov S, Riley C, Keffler J, Yu J, Kindy M, Macklin W, et al. SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY. J Biol Chem. 2016;291:1957-73 pubmed publisher
Separovic D, Breen P, Joseph N, Bielawski J, Pierce J, Van Buren E, et al. siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy. Anticancer Res. 2012;32:2479-2485 pubmed
Separovic D, Breen P, Joseph N, Bielawski J, Pierce J, Van Buren E, et al. Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells. Anticancer Res. 2012;32:753-60 pubmed
Mullen T, Spassieva S, Jenkins R, Kitatani K, Bielawski J, Hannun Y, et al. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism. J Lipid Res. 2011;52:68-77 pubmed publisher
Siskind L, Mullen T, Romero Rosales K, Clarke C, Hernandez Corbacho M, Edinger A, et al. The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis. J Biol Chem. 2010;285:11818-26 pubmed publisher

product information

master code :

H00029956-M01A

SKU :

H00029956-M01A

product name :

LASS2 Antibody (1A6)

unit size :

0.2 ml

description :

The LASS2 Antibody (1A6) from Novus is a mouse monoclonal antibody to LASS2. This antibody reacts with human,mouse. The LASS2 Antibody (1A6) has been validated for the following applications: IF/IHC,Western Blot,ELISA,Immunohistochemistry.

target :

LASS2

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

1A6

conjugate :

Unconjugated

host :

Mouse

immunogen :

MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDL
YITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRA
PPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERW
FRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVD
KPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLF
SIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTL
IMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFI
ITRLVILPFWILHCTLVYPLELYPAFFGYYFFNSMMGVL
QLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEG
EEAAAGGGAKSRPLANGHPILNNNHRKND
LASS2 (AAH01357, 1 a.a. ~ 380 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgM Kappa

purity :

Unpurified

species :

Human,Mouse

specificity :

LASS2 - LAG1 longevity assurance homolog 2 (S

gene symbol :

CERS2

accessionNumbers :

AAH01357

applications :

IF/IHC,Western Blot,ELISA,Immunohistochemistry

USD :

529 USD

alt names :

ceramide synthase 2, CerS2, LAG1 homolog, ceramide synthase 2, LAG1 longevity assurance 2, LAG1 longevity assurance homolog 2, LAG1 longevity assurance homolog 2 (S. cerevisiae), S. cerevisiae) homolog 2, SP260MGC987, TMSG1, Tumor metastasis-suppressor gene 1 protein

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage