product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
OCIL/CLEC2d Antibody (4C7) - Azide and BSA Free
catalog :
H00029121-M01
quantity :
0.1 mg
price :
519 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C7
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Reference
de Vicente J, Lequerica Fern xe1 ndez P, Rodrigo J, Rodr xed guez Santamarta T, Blanco Lorenzo V, Prieto Fern xe1 ndez L, et al. Lectin-like Transcript-1 (LLT1) Expression in Oral Squamous Cell Carcinomas: Prognostic Significance and Relationship with the Tumor Immune Microenvironment. Int J Mol Sci. 2024;25: pubmed publisher
Sánchez Canteli M, Hermida Prado F, Sordo Bahamonde C, Montoro Jim xe9 nez I, Pozo Agundo E, Allonca E, et al. Lectin-Like Transcript 1 (LLT1) Checkpoint: A Novel Independent Prognostic Factor in HPV-Negative Oropharyngeal Squamous Cell Carcinoma. Biomedicines. 2020;8: pubmed publisher
Williams K, Eaton H, Jones L, Rengan S, Burshtyn D. Vaccinia virus Western Reserve induces rapid surface expression of a host molecule detected by the antibody 4C7 that is distinct from CLEC2D. Microbiol Immunol. 2016;60:754-769 pubmed publisher
Chalan P, Bijzet J, Huitema M, Kroesen B, Brouwer E, Boots A. Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis. PLoS ONE. 2015;10:e0132436 pubmed publisher
Satkunanathan S, Kumar N, Bajorek M, Purbhoo M, Culley F. Respiratory syncytial virus infection, TLR3 ligands, and proinflammatory cytokines induce CD161 ligand LLT1 expression on the respiratory epithelium. J Virol. 2014;88:2366-73 pubmed publisher
Germain C, Meier A, Jensen T, Knapnougel P, Poupon G, Lazzari A, et al. Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-? contributes to modulate immune responses. J Biol Chem. 2011;286:37964-75 pubmed publisher
Germain C, Bihl F, Zahn S, Poupon G, Dumaurier M, Rampanarivo H, et al. Characterization of alternatively spliced transcript variants of CLEC2D gene. J Biol Chem. 2010;285:36207-15 pubmed publisher
Rosen D, Cao W, Avery D, Tangye S, Liu Y, Houchins J, et al. Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. J Immunol. 2008;180:6508-17 pubmed
Roth P, Mittelbronn M, Wick W, Meyermann R, Tatagiba M, Weller M. Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1. Cancer Res. 2007;67:3540-4 pubmed
product information
master code :
H00029121-M01
SKU :
H00029121-M01
product name :
OCIL/CLEC2d Antibody (4C7) - Azide and BSA Free
unit size :
0.1 mg
description :
The OCIL/CLEC2d Antibody (4C7) - Azide and BSA Free from Novus is a mouse monoclonal antibody to OCIL/CLEC2d. This antibody reacts with human. The OCIL/CLEC2d Antibody (4C7) - Azide and BSA Free has been validated for the following applications: Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Western Blot.
target :
OCIL/CLEC2d
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
4C7
conjugate :
Unconjugated
host :
Mouse
immunogen :
MHDSNNVEKDITPSELPANPGCVHSKEHSIKATLIWRLF
FLIMFLTIIVCGMVAALSAIRANCHQEPSVCLQAACPES
WIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQ
ELNFLLRYKGPSDHWIGLSREQGQPWKWINGTEWTRQ
CLEC2D (AAH19883, 1 a.a. ~ 154 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human
specificity :
CLEC2D - C-type lectin superfamily 2, member D
gene symbol :
CLEC2D
accessionNumbers :
AAH19883
applications :
Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Western Blot
USD :
519 USD
alt names :
CLAXLLT-1, C-type lectin domain family 2 member D, C-type lectin domain family 2, member D, C-type lectin related f, Lectin-like NK cell receptor, Lectin-like transcript 1, LLT1Osteoclast inhibitory lectin, OCILmember D
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.