product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
BRMS1 Antibody (2D4-2G11) - Azide and BSA Free
catalog :
H00025855-M01
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D4-2G11
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 10
Reference
Ventura B, Quezada C, Maloney S, Fernandes B, Antecka E, Martins C, et al. Expression of the metastasis suppressor BRMS1 in uveal melanoma. Ecancermedicalscience. 2014;8:410 pubmed publisher
Liu Y, Mayo M, Nagji A, Hall E, Shock L, Xiao A, et al. BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300. Cancer Res. 2013;73:1308-17 pubmed publisher
Cui R, Liu N, He Q, Li W, Huang B, Sun Y, et al. Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival. BMC Cancer. 2012;12:376 pubmed publisher
Kim B, Nam H, Pyo K, Jang M, Kim I, Kim D, et al. Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex. Biochem Biophys Res Commun. 2011;415:720-6 pubmed publisher
Nagji A, Liu Y, Stelow E, Stukenborg G, Jones D. BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer. J Pathol. 2010;221:229-37 pubmed publisher
Smith P, Liu Y, Siefert S, Moskaluk C, Petroni G, Jones D. Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer. Cancer Lett. 2009;276:196-203 pubmed publisher
Rivera J, Megias D, Bravo J. Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1. J Proteome Res. 2007;6:4006-18 pubmed
Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2006;351:602-11 pubmed
Liu Y, Smith P, Jones D. Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. Mol Cell Biol. 2006;26:8683-96 pubmed
Hudelist G, Singer C, Pischinger K, Kaserer K, Manavi M, Kubista E, et al. Proteomic analysis in human breast cancer: identification of a characteristic protein expression profile of malignant breast epithelium. Proteomics. 2006;6:1989-2002 pubmed
product information
master code :
H00025855-M01
SKU :
H00025855-M01
product name :
BRMS1 Antibody (2D4-2G11) - Azide and BSA Free
unit size :
0.1 mg
description :
The BRMS1 Antibody (2D4-2G11) - Azide and BSA Free from Novus is a mouse monoclonal antibody to BRMS1. This antibody reacts with human. The BRMS1 Antibody (2D4-2G11) - Azide and BSA Free has been validated for the following applications: Western Blot,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Sandwich ELISA.
target :
BRMS1
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2D4-2G11
conjugate :
Unconjugated
host :
Mouse
immunogen :
MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQT
ESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKL
FRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQ
VAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTL
QGELQERIQRLEEDRQSLDLSSEWWDDKLHARGSSRSWD
SLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARA
AVSPQKRKSDGP
BRMS1 (AAH09834, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human
specificity :
BRMS1 - breast cancer metastasis suppressor 1
gene symbol :
BRMS1
accessionNumbers :
AAH09834
applications :
Western Blot,ELISA,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Sandwich ELISA
USD :
499 USD
alt names :
breast cancer metastasis suppressor 1, breast cancer metastasis-suppressor 1, DKFZP564A063
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.