NT5C2 Antibody (3C1) | Novus Biologicals H00022978-M02 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NT5C2 Antibody (3C1)

catalog :

H00022978-M02

quantity :

0.1 mg

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3C1

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 8

Reference
Raza M, Cadassou O, Dumontet C, Cros Perrial E, Jordheim L. CD73 and cN-II regulate the cellular response to chemotherapeutic and hypoxic stress in lung adenocarcinoma cells. Biochim Biophys Acta Gen Subj. 2021;1865:129842 pubmed publisher
Cadassou O, Raza M, Machon C, Gudefin L, Armanet C, Chettab K, et al. Enhanced migration of breast and lung cancer cells deficient for cN-II and CD73 via COX-2/PGE2/AKT axis regulation. Cell Oncol (Dordr). 2020;: pubmed publisher
Duarte R, Bachtel N, Cotel M, Lee S, Selvackadunco S, Watson I, et al. The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells. Biol Psychiatry. 2019;: pubmed publisher
Schneider C, Oellerich T, Baldauf H, Schwarz S, Thomas D, Flick R, et al. SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. Nat Med. 2017;23:250-255 pubmed publisher
Cividini F, Cros Perrial E, Pesi R, Machon C, Allegrini S, Camici M, et al. Cell proliferation and drug sensitivity of human glioblastoma cells are altered by the stable modulation of cytosolic 5'-nucleotidase II. Int J Biochem Cell Biol. 2015;65:222-9 pubmed publisher
Jordheim L, Puy J, Cros Perrial E, Peyrottes S, Lefebvre I, PÃ©rigaud C, et al. Determination of the enzymatic activity of cytosolic 5'-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models. Anal Bioanal Chem. 2015;407:5747-58 pubmed publisher
Cividini F, Tozzi M, Galli A, Pesi R, Camici M, Dumontet C, et al. Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf. PLoS ONE. 2015;10:e0121525 pubmed publisher
Kulkarni S, Karlsson H, Szekeres F, Chibalin A, Krook A, Zierath J. Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle. J Biol Chem. 2011;286:34567-74 pubmed publisher

product information

brand :

Novus

master code :

H00022978-M02

SKU :

H00022978-M02

product name :

NT5C2 Antibody (3C1)

unit size :

0.1 mg

seo description :

The NT5C2 Antibody (3C1) - Azide and BSA Free from Novus is a mouse monoclonal antibody to NT5C2. This antibody reacts with human. The NT5C2 Antibody (3C1) - Azide and BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.

target :

NT5C2

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

3C1

conjugate :

Unconjugated

dilution :

Western Blot 1:500, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

host :

Mouse

immunogen :

MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNR
SLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLV
SIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGN
LLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTL
FNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYR
SMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPL
LLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPG
SSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKL
KIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGD
HIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFE
ELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHD
MDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINL
LYYPFSYLFRAAHVLMPHESTVEHTHVDINEMESPLATR
NRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITH
CHDEDDDEEEEEEEE
NT5C2 (AAH01595, 1 a.a. ~ 561 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2a Kappa

purity :

IgG purified

species :

Human

specificity :

NT5C2 - 5 -nucleotidase, cytosolic II

gene symbol :

NT5C2

accessionNumbers :

AAH01595

applications :

ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence

USD :

499 USD

alt names :

5'-nucleotidase (purine), cytosolic type B, 5'-nucleotidase, cytosolic II, cN-II, Cytosolic 5'-nucleotidase II, EC 3.1.3, EC 3.1.3.5, GMP, NT5BIMP-specific 5'-NT, NT5CP, PNT5cytosolic purine 5'-nucleotidase, purine 5' nucleotidase

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage