TC21/R-Ras2 Antibody (2D3-4B8) | Novus Biologicals H00022800-M01-100ug product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TC21/R-Ras2 Antibody (2D3-4B8)

catalog :

H00022800-M01-100ug

quantity :

100 ug

price :

529 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D3-4B8

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 5

Reference
Hortal A, Oeste C, Cifuentes C, Alcoceba M, Fernández Pisonero I, Clavain L, et al. Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia. Mol Cancer. 2022;21:35 pubmed publisher
Lazar S, Wurtzel J, Chen X, Ma P, Goldfinger L. High-efficiency unassisted transfection of platelets with naked double-stranded miRNAs modulates signal-activated translation and platelet function. Platelets. 2021;32:794-806 pubmed publisher
Janapati S, Wurtzel J, Dangelmaier C, Manne B, Bhavanasi D, Kostyak J, et al. TC21/RRas2 regulates glycoprotein VI-FcRγ-mediated platelet activation and thrombus stability. J Thromb Haemost. 2018;: pubmed publisher
Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed publisher
Patmore D, Welch S, Fulkerson P, Wu J, Choi K, Eaves D, et al. In vivo regulation of TGF-? by R-Ras2 revealed through loss of the RasGAP protein NF1. Cancer Res. 2012;72:5317-27 pubmed publisher

product information

brand :

Novus

master code :

H00022800-M01

SKU :

H00022800-M01-100ug

product name :

TC21/R-Ras2 Antibody (2D3-4B8)

unit size :

100 ug

seo description :

The TC21/R-Ras2 Antibody (2D3-4B8) - Azide and BSA Free from Novus is a mouse monoclonal antibody to TC21/R-Ras2. This antibody reacts with human,mouse,rat. The TC21/R-Ras2 Antibody (2D3-4B8) - Azide and BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.

target :

TC21/R-Ras2

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

2D3-4B8

conjugate :

Unconjugated

dilution :

Western Blot 1:500, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/ Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Knockdown Validated

host :

Mouse

immunogen :

MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYF
VTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAM
REQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDR
DEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEA
SAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKD
KKGCHCVIF
RRAS2 (AAH13106, 1 a.a. ~ 204 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG1 Kappa

purity :

IgG purified

species :

Human,Mouse,Rat

specificity :

RRAS2 - related RAS viral (r-ras) oncogene homolog 2

gene symbol :

RRAS2

accessionNumbers :

AAH13106

applications :

ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence

USD :

529 USD

alt names :

ras-related protein R-Ras2, related RAS viral (r-ras) oncogene homolog 2, TC21Ras-like protein TC21, Teratocarcinoma oncogene

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage