product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MTHFD2 Antibody (4G7-2G3) - Azide and BSA Free
catalog :
H00010797-M01
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G7-2G3
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 4
Reference
Wang Y, Hongu T, Nishimura T, Takeuchi Y, Takano H, Daikoku T, et al. Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy. Biochem Biophys Res Commun. 2023;674:183-189 pubmed publisher
Yao S, Peng L, Elakad O, Küffer S, Hinterthaner M, Danner B, et al. One carbon metabolism in human lung cancer. Transl Lung Cancer Res. 2021;10:2523-2538 pubmed publisher
Gustafsson Sheppard N, Jarl L, Mahadessian D, Strittmatter L, Schmidt A, Madhusudan N, et al. The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation. Sci Rep. 2015;5:15029 pubmed publisher
Nilsson R, Jain M, Madhusudhan N, Sheppard N, Strittmatter L, Kampf C, et al. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer. Nat Commun. 2014;5:3128 pubmed publisher
product information
brand :
Novus
catalog number base :
H00010797-M01
SKU :
H00010797-M01
product name :
MTHFD2 Antibody (4G7-2G3) - Azide and BSA Free
units size :
0.1 mg
description :
The MTHFD2 Antibody (4G7-2G3) - Azide and BSA Free from Novus is a mouse monoclonal antibody to MTHFD2. This antibody reacts with human. The MTHFD2 Antibody (4G7-2G3) - Azide and BSA Free has been validated for the following applications: IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin.
target :
MTHFD2
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
4G7-2G3
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
host :
Mouse
immunogen :
SLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEW
VASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINS
ETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEH
IDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATP
WGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTD
GAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAG
IPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVD
FEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLR
LEEREVLKSKELGVATN
MTHFD2 (AAH01548, 16 a.a. ~ 344 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2a Kappa
purity :
IgG purified
species :
Human
specificity :
CHMP2B - chromatin modifying protein 2B
gene symbol :
MTHFD2
top caption :
Western Blot: MTHFD2 Antibody (4G7-2G3) [H00010797-M01]
accessionNumbers :
AAH01548
applications :
IF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
499 USD
alt names :
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, methenyltetrahydrofolate cyclohydrolase, methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, mitochondrial, NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase, NMDMC
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.