This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
AG-2/AGR2 Antibody (1C3)
catalog :
H00010551-M03
quantity :
0.1 mg
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1C3
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 12
Reference
Sommerova L, Ondrousková E, Vojtesek B, Hrstka R. Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition. BMC Cancer. 2017;17:546 pubmed publisher
Procházková I, Lenco J, Fucikova A, Dresler J, Čápková L, Hrstka R, et al. Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. Biochim Biophys Acta Proteins Proteom. 2017;1865:488-498 pubmed publisher
Ahmad R, Nicora C, Shukla A, Smith R, Qian W, Liu A. An efficient method for native protein purification in the selected range from prostate cancer tissue digests. Chin Clin Oncol. 2016;5:78 pubmed publisher
Dong A, Wodziak D, Lowe A. Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem. 2015;290:8016-27 pubmed publisher
Riener M, Thiesler T, Hellerbrand C, Amann T, Cathomas G, Fritzsche F, et al. Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas. Eur J Cancer. 2014;50:1722-1730 pubmed publisher
Gray T, Murray E, Nowicki M, Remnant L, Scherl A, Muller P, et al. Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein. Protein Sci. 2013;22:1266-78 pubmed publisher
Darb Esfahani S, Fritzsche F, Kristiansen G, Weichert W, Sehouli J, Braicu I, et al. Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma. Virchows Arch. 2012;461:109-16 pubmed publisher
Wayner E, Quek S, Ahmad R, Ho M, Loprieno M, Zhou Y, et al. Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine. Prostate. 2012;72:1023-34 pubmed publisher
Lepreux S, Bioulac Sage P, Chevet E. Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree. Liver Int. 2011;31:322-8 pubmed publisher
Maslon M, Hrstka R, Vojtesek B, Hupp T. A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin. J Mol Biol. 2010;404:418-38 pubmed publisher
Ambolet Camoit A, Bui L, Pierre S, Chevallier A, Marchand A, Coumoul X, et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2. Toxicol Sci. 2010;115:501-12 pubmed publisher
Zhao L, Lee B, Brown D, Molloy M, Marx G, Pavlakis N, et al. Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling. Cancer Res. 2009;69:7696-703 pubmed publisher
product information
brand :
Novus
master code :
H00010551-M03
SKU :
H00010551-M03
product name :
AG-2/AGR2 Antibody (1C3)
description :
The AG-2/AGR2 Antibody (1C3) from Novus Biologicals is a mouse monoclonal antibody to AG-2/AGR2. This antibody reacts with human. The AG-2/AGR2 Antibody (1C3) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA.
target :
AG-2/AGR2
category :
Primary Antibodies
unit size :
0.1 mg
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
1C3
conjugate :
Unconjugated
host :
Mouse
immunogen :
MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPK
LPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHL
DECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKH
LSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPAD
TALLLDNMKKALKLLKTEL
AGR2 (AAH15503.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2b Kappa
purity :
Protein A purified
species :
Human
specificity :
AGR2 - anterior gradient 2 homolog (Xenopus laevis)
gene symbol :
AGR2
catalog number base :
H00010551-M03
accessionNumbers :
AAH15503
applications :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA
2020 USD :
399
2021 USD :
399 USD
alt names :
AG-2, AG2member 17, anterior gradient 2 homolog (Xenopus laevis), anterior gradient homolog 2 (Xenopus laevis), GOB-4, hAG-2, HPC8, secreted cement gland homolog
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.