DRP1 Antibody (3B5) - Azide and BSA Free | Novus Biologicals H00010059-M01 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DRP1 Antibody (3B5) - Azide and BSA Free

catalog :

H00010059-M01

quantity :

0.1 mg

price :

529 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B5

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Aimaretti E, Chimienti G, Rubeo C, Di Lorenzo R, Trisolini L, Dal Bello F, et al. Different Effects of High-Fat/High-Sucrose and High-Fructose Diets on Advanced Glycation End-Product Accumulation and on Mitochondrial Involvement in Heart and Skeletal Muscle in Mice. Nutrients. 2023;15: pubmed publisher
Wang X, Myakala K, Libby A, Krawczyk E, Panov J, Jones B, et al. Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney. Am J Pathol. 2023;193:1969-1987 pubmed publisher
Jaroslawska J, Gospodarska E, Korytko A. Increasing energy expenditure through exercise and low ambient temperature offers oxidative protection to the hypothalamus after high-fat feeding to mice. J Neuroendocrinol. 2022;34:e13095 pubmed publisher
Tsushima K, Bugger H, Wende A, Soto J, Jenson G, Tor A, et al. Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission. Circ Res. 2018;122:58-73 pubmed publisher
Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, et al. Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. Exp Gerontol. 2017;98:99-109 pubmed publisher
Cormio A, Musicco C, Gasparre G, Cormio G, Pesce V, Sardanelli A, et al. Increase in proteins involved in mitochondrial fission, mitophagy, proteolysis and antioxidant response in type I endometrial cancer as an adaptive response to respiratory complex I deficiency. Biochem Biophys Res Commun. 2017;491:85-90 pubmed publisher
Kim B, McLean L, Philip S, Feldman E. Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons. Endocrinology. 2011;152:3638-47 pubmed publisher
Vincent A, Edwards J, McLean L, Hong Y, Cerri F, Lopez I, et al. Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy. Acta Neuropathol. 2010;120:477-89 pubmed publisher
Edwards J, Quattrini A, Lentz S, Figueroa Romero C, Cerri F, Backus C, et al. Diabetes regulates mitochondrial biogenesis and fission in mouse neurons. Diabetologia. 2010;53:160-9 pubmed publisher
Figueroa Romero C, INIGUEZ LLUHI J, Stadler J, Chang C, Arnoult D, Keller P, et al. SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB J. 2009;23:3917-27 pubmed publisher

product information

master code :

H00010059-M01

SKU :

H00010059-M01

product name :

DRP1 Antibody (3B5) - Azide and BSA Free

unit size :

0.1 mg

description :

The DRP1 Antibody (3B5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to DRP1. This antibody reacts with human,mouse,rat. The DRP1 Antibody (3B5) - Azide and BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.

target :

DRP1

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

3B5

conjugate :

Unconjugated

host :

Mouse

immunogen :

MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKS
SVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKT
TGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETER
ISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVG
DQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSE
ALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRV
IPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKY
PSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLA
AQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGT
AKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTI
DILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSL
RCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVV
TCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGL
MNNNIEEQRRNRLARELPSAVSRDKLIQDSRRETKNVAS
GGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIP
IMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERL
IKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQ
LYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIA
EIRETHLW
DNM1L (AAH24590.1, 1 a.a. ~ 710 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2b Kappa

purity :

IgG purified

species :

Human,Mouse,Rat

specificity :

DNM1L - dynamin 1-like

gene symbol :

DNM1L

accessionNumbers :

AAH24590

applications :

ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence

USD :

529 USD

alt names :

DLP1, DRP1Dnm1p/Vps1p-like protein, DVLPEC 3.6.5.5, Dymple, DYMPLEDYNIV-11, dynamin 1-like, Dynamin family member proline-rich carboxyl-terminal domain less, dynamin-1-like protein, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, FLJ41912, HDYNIV, VPS1

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage