product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DNAJB6 Antibody (2C11-C1) - Azide and BSA Free
catalog :
H00010049-M01
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2C11-C1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 9
Reference
Folke J, Arkan S, Martinsson I, Aznar S, Gouras G, Brudek T, et al. DNAJB6b is Downregulated in Synucleinopathies. J Parkinsons Dis. 2021;11:1791-1803 pubmed publisher
Qian F, Guo Y, Zu J, Zhang J, Zheng Y, Abdoulaye I, et al. A novel recessive mutation affecting DNAJB6a causes myofibrillar myopathy. Acta Neuropathol Commun. 2021;9:23 pubmed publisher
Palmio J, Jonson P, Inoue M, Sarparanta J, Bengoechea R, Savarese M, et al. Mutations in the J domain of DNAJB6 cause dominant distal myopathy. Neuromuscul Disord. 2020;30:38-46 pubmed publisher
Hong Y, Hong Y, Choi Y, Yeo S, Jin S, Lee S, et al. The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss. Oxid Med Cell Longev. 2017;2017:7982389 pubmed publisher
Ding Y, Long P, Bos J, Shih Y, Ma X, Sundsbak R, et al. A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene. JCI Insight. 2016;1: pubmed
Bengoechea R, Pittman S, Tuck E, True H, Weihl C. Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D. Hum Mol Genet. 2015;24:6588-602 pubmed publisher
Stein K, Bengoechea R, Harms M, Weihl C, True H. Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers. J Biol Chem. 2014;289:21120-30 pubmed
Blandin G, Marchand S, Charton K, Daniele N, Gicquel E, Boucheteil J, et al. A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. Skelet Muscle. 2013;3:3 pubmed publisher
de Bock C, Lin Z, Mekkawy A, Byrne J, Wang Y. Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion. Int J Oncol. 2010;36:1155-63 pubmed
product information
master code :
H00010049-M01
SKU :
H00010049-M01
product name :
DNAJB6 Antibody (2C11-C1) - Azide and BSA Free
unit size :
0.1 mg
description :
The DNAJB6 Antibody (2C11-C1) - Azide and BSA Free from Novus is a mouse monoclonal antibody to DNAJB6. This antibody reacts with human. The DNAJB6 Antibody (2C11-C1) - Azide and BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Frozen,ELISA,Immunohistochemistry,ICC/IF (Negative).
target :
DNAJB6
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2C11-C1
conjugate :
Unconjugated
host :
Mouse
immunogen :
MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENK
EEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGG
GGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFED
PFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSS
FDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSISTST
KMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGKEQ
LLRLDNK
DNAJB6 (AAH00177, 1 a.a. ~ 241 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human
specificity :
DNAJB6 - DnaJ (Hsp40) homolog, subfamily B, member 6
gene symbol :
DNAJB6
accessionNumbers :
AAH00177
applications :
IF/IHC,Western Blot,Immunohistochemistry-Frozen,ELISA,Immunohistochemistry,ICC/IF (Negative)
USD :
499 USD
alt names :
DJ4, DKFZp566D0824, DnaJ, DnaJ (Hsp40) homolog, subfamily B, member 6, dnaJ homolog subfamily B member 6, DnaJ-like 2 protein, FLJ42837, Heat shock protein J2, HHDJ1, HSJ2, HSJ-2, MGC1152, MRJMGC117297, MSJ1, MSJ-1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.