Sphingosine Kinase 1/SPHK1 Antibody (1D6) - Azide and BSA Free | Novus Biologicals H00008877-M01 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Sphingosine Kinase 1/SPHK1 Antibody (1D6) - Azide and BSA Free

catalog :

H00008877-M01

quantity :

0.1 mg

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D6

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 12

Reference
Fraunhoffer N, Abuelafia A, Bigonnet M, Gayet O, Roques J, Nicolle R, et al. Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction. NPJ Precis Oncol. 2022;6:57 pubmed publisher
Kim M, Park J, Lee E, Kim S, Shin S, Ahn J, et al. C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation. Oncol Rep. 2018;40:2977-2987 pubmed publisher
Zhang H, Wang Q, Zhao Q, Di W. MiR-124 inhibits the migration and invasion of ovarian cancer cells by targeting SphK1. J Ovarian Res. 2013;6:84 pubmed publisher
Bohm A, Flößer A, Ermler S, Fender A, Lüth A, Kleuser B, et al. Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells. Cardiovasc Res. 2013;99:505-13 pubmed publisher
Sheu J, Lee C, Hua C, Li C, Lai M, Lee S, et al. LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling. Oncogene. 2014;33:1375-84 pubmed publisher
Schröder M, Richter C, Juan M, Maltusch K, Giegold O, Quintini G, et al. The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen. Mol Immunol. 2011;48:1139-48 pubmed publisher
Asher V, Warren A, Shaw R, Sowter H, Bali A, Khan R. The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. Cancer Cell Int. 2011;11:6 pubmed publisher
Ali Rahmani F, Hengst J, Connor J, Schengrund C. Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells. Neurochem Res. 2011;36:1687-96 pubmed publisher
Schenten V, Melchior C, Steinckwich N, Tschirhart E, Bréchard S. Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9. J Leukoc Biol. 2011;89:587-96 pubmed publisher
Sinha U, Schorn V, Hochstim C, Chinn S, Zhu S, Masood R. Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition. Head Neck. 2011;33:178-88 pubmed publisher
Wang S, Zhang Z, Lin X, Xu D, Feng Y, Ding K. A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. Glycobiology. 2010;20:473-84 pubmed publisher
Billich A, Urtz N, Reuschel R, Baumruker T. Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells. Int J Biochem Cell Biol. 2009;41:1547-55 pubmed publisher

product information

master code :

H00008877-M01

SKU :

H00008877-M01

product name :

Sphingosine Kinase 1/SPHK1 Antibody (1D6) - Azide and BSA Free

unit size :

0.1 mg

description :

The Sphingosine Kinase 1/SPHK1 Antibody (1D6) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Sphingosine Kinase 1/SPHK1. This antibody reacts with human. The Sphingosine Kinase 1/SPHK1 Antibody (1D6) - Azide and BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence.

target :

Sphingosine Kinase 1/SPHK1

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

1D6

conjugate :

Unconjugated

host :

Mouse

immunogen :

MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQ
PLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVM
SGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALA
ASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLH
TASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLG
TFLLLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPV
DAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMF
AAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHM
EYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQ
GQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL
SPHK1 (AAH08040, 1 a.a. ~ 384 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2a Kappa

purity :

IgG purified

species :

Human

specificity :

SPHK1 (1D6)

gene symbol :

SPHK1

accessionNumbers :

AAH08040

applications :

Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence

USD :

499 USD

alt names :

EC 2.7.1.91, sphingosine kinase 1, SPHKSK 1, SPK, SPK 1

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage