product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
E6AP/UBE3A Antibody (2F6) - Azide and BSA Free
catalog :
H00007337-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2F6
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Novus Biologicals product webpage
citations: 4
Reference
Sen D, Drobna Z, Keung A. Evaluation of UBE3A antibodies in mice and human cerebral organoids. Sci Rep. 2021;11:6323 pubmed publisher
Li S, Hong X, Wei Z, Xie M, Li W, Liu G, et al. Ubiquitination of the HPV Oncoprotein E6 Is Critical for E6/E6AP-Mediated p53 Degradation. Front Microbiol. 2019;10:2483 pubmed publisher
Spangle J, Ghosh Choudhury N, Munger K. Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. J Virol. 2012;86:7466-72 pubmed publisher
Underbrink M, Howie H, Bedard K, Koop J, Galloway D. E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation. J Virol. 2008;82:10408-17 pubmed publisher
product information
master code :
H00007337-M01
SKU :
H00007337-M01
product name :
E6AP/UBE3A Antibody (2F6) - Azide and BSA Free
unit size :
0.1 mg
description :
The E6AP/UBE3A Antibody (2F6) - Azide and BSA Free from Novus is a mouse monoclonal antibody to E6AP/UBE3A. This antibody reacts with human,mouse,rat. The E6AP/UBE3A Antibody (2F6) - Azide and BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated.
target :
E6AP/UBE3A
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2F6
conjugate :
Unconjugated
host :
Mouse
immunogen :
ETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVY
YANVVGGEVDTNHNEEDDEEPIPESSELTLQELLGEERR
NKKGPRVDPLETELGVKTLDCR
UBE3A (AAH09271, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2a Kappa
purity :
IgG purified
species :
Human,Mouse,Rat
specificity :
UBE3A - ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
gene symbol :
UBE3A
Antibody validation :
Knockout/Knockdown
accessionNumbers :
AAH09271
applications :
Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated
USD :
529 USD
alt names :
ANCREPVE6AP, AS, CTCL tumor antigen se37-2, E6AP, E6-AP, E6AP ubiquitin-protein ligase, EC 6.3.2.-, FLJ26981, HPVE6A, human papilloma virus E6-associated protein, Human papillomavirus E6-associated protein, Oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54, ubiquitin protein ligase E3A, ubiquitin-protein ligase E3A
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.