Rheb Antibody (2C11) | Novus Biologicals H00006009-M01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Rheb Antibody (2C11)

catalog :

H00006009-M01

quantity :

0.1 mg

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C11

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

citations: 6

Reference
Deng L, Chen L, Zhao L, Xu Y, Peng X, Wang X, et al. Ubiquitination of Rheb governs growth factor-induced mTORC1 activation. Cell Res. 2019;29:136-150 pubmed publisher
Hoxhaj G, Hughes Hallett J, Timson R, Ilagan E, Yuan M, Asara J, et al. The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels. Cell Rep. 2017;21:1331-1346 pubmed publisher
Tian Q, Gromov P, Clement J, Wang Y, Riemann M, Weih F, et al. RHEB1 insufficiency in aged male mice is associated with stress-induced seizures. GeroScience. 2017;39:557-570 pubmed publisher
Jacobs B, McNally R, Kim K, Blanco R, Privett R, You J, et al. Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling. J Biol Chem. 2017;292:6987-6997 pubmed publisher
Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
Menon S, Dibble C, Talbott G, Hoxhaj G, Valvezan A, Takahashi H, et al. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome. Cell. 2014;156:771-85 pubmed publisher

product information

brand :

Novus

master code :

H00006009-M01

SKU :

H00006009-M01

product name :

Rheb Antibody (2C11)

description :

The Rheb Antibody (2C11) from Novus Biologicals is a mouse monoclonal antibody to Rheb. This antibody reacts with human, mouse, rat. The Rheb Antibody (2C11) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Sandwich ELISA.

target :

Rheb

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

2C11

conjugate :

Unconjugated

host :

Mouse

immunogen :

MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTI
ENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDI
NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLV
GNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTA
VDVFRRIILEAEKMDGAASQGKSSCSVM
RHEB (AAH16155, 1 a.a. ~ 184 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG1 Kappa

purity :

IgG purified

species :

Human, Mouse, Rat

specificity :

RHEB - Ras homolog enriched in brain (2C11)

gene symbol :

RHEB

catalog number base :

H00006009-M01

accessionNumbers :

AAH16155

applications :

Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Sandwich ELISA

2020 USD :

399

2021 USD :

399 USD

alt names :

GTP-binding protein Rheb, MGC111559, Ras homolog enriched in brainRHEB2Ras homolog enriched in brain 2

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.