Notch-3 Antibody (1G5) | Novus Biologicals H00004854-M01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Notch-3 Antibody (1G5)

catalog :

H00004854-M01

quantity :

0.1 mg

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G5

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 9

Reference
Nagatoshi A, Ueda M, Ueda A, Tasaki M, Inoue Y, Ma Y, et al. Serum amyloid P component: A novel potential player in vessel degeneration in CADASIL. J Neurol Sci. 2017;379:69-76 pubmed publisher
Zhang X, Wang Y, Zhu J, Liu X, You H, Gong M, et al. N-acetylcysteine negatively regulates Notch3 and its malignant signaling. Oncotarget. 2016;7:30855-66 pubmed publisher
Meng H, Zhang X, Lee S, Wang M. Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling. PLoS ONE. 2013;8:e75808 pubmed publisher
Dong H, Blaivas M, Wang M. Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Brain Res. 2012;1456:64-71 pubmed publisher
Tada M, Itoh S, Ishii Watabe A, Suzuki T, Kawasaki N. Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome. FEBS J. 2012;279:2096-107 pubmed publisher
Lee S, Meng H, Elmadhoun O, Blaivas M, Wang M. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication. Arch Neurol. 2011;68:1584-6 pubmed publisher
Watanabe Hosomi A, Watanabe Y, Tanaka M, Nakagawa M, Mizuno T. Transendocytosis is impaired in CADASIL-mutant NOTCH3. Exp Neurol. 2012;233:303-11 pubmed publisher
Meng H, Zhang X, Hankenson K, Wang M. Thrombospondin 2 potentiates notch3/jagged1 signaling. J Biol Chem. 2009;284:7866-74 pubmed publisher
Park J, Shih I, Wang T. Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Res. 2008;68:8852-60 pubmed publisher

product information

brand :

Novus

master code :

H00004854-M01

SKU :

H00004854-M01

product name :

Notch-3 Antibody (1G5)

description :

The Notch-3 Antibody (1G5) from Novus Biologicals is a mouse monoclonal antibody to Notch-3. This antibody reacts with human. The Notch-3 Antibody (1G5) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Sandwich ELISA.

target :

Notch-3

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

1G5

conjugate :

Unconjugated

host :

Mouse

immunogen :

SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSG
PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCL
SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR
NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2a Kappa

purity :

IgG purified

species :

Human

specificity :

NOTCH3 - Notch homolog 3 (Drosophila)

gene symbol :

NOTCH3

catalog number base :

H00004854-M01

accessionNumbers :

NP_000426

applications :

Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Sandwich ELISA

2020 USD :

399

2021 USD :

399 USD

alt names :

CADASIL, CASILneurogenic locus notch homolog protein 3, Notch (Drosophila) homolog 3, notch 3Notch homolog 3 (Drosophila), Notch homolog 3

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.