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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lysyl Oxidase Homolog 2/LOXL2 Antibody (5D2) - Azide and BSA Free
catalog :
H00004017-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5D2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
citations: 6
Reference
Umana Diaz C, Pichol Thievend C, Marchand M, Atlas Y, Salza R, Malbouyres M, et al. Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms. Matrix Biol. 2020;88:33-52 pubmed publisher
Schmelzer C, Heinz A, Troilo H, Lockhart Cairns M, Jowitt T, Marchand M, et al. Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin. FASEB J. 2019;33:5468-5481 pubmed publisher
Zhan X, Jiao J, Zhang H, Li C, Zhao J, Liao L, et al. A three-gene signature from protein-protein interaction network of LOXL2- and actin-related proteins for esophageal squamous cell carcinoma prognosis. Cancer Med. 2017;6:1707-1719 pubmed publisher
Li T, Xu L, Wu Z, Liao L, SHEN J, Xu X, et al. Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma. Hum Pathol. 2012;43:1068-76 pubmed publisher
Li T, Li D, Cheng L, Wu H, Gao Z, Liu Z, et al. Epithelial-mesenchymal transition induced by hepatitis C virus core protein in cholangiocarcinoma. Ann Surg Oncol. 2010;17:1937-44 pubmed publisher
Fujimoto E, Tajima S. Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes. J Dermatol Sci. 2009;55:91-8 pubmed publisher
product information
master code :
H00004017-M01
SKU :
H00004017-M01
product name :
Lysyl Oxidase Homolog 2/LOXL2 Antibody (5D2) - Azide and BSA Free
unit size :
0.1 mg
description :
The Lysyl Oxidase Homolog 2/LOXL2 Antibody (5D2) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Lysyl Oxidase Homolog 2/LOXL2. This antibody reacts with human,mouse. The Lysyl Oxidase Homolog 2/LOXL2 Antibody (5D2) - Azide and BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Sandwich ELISA,Immunocytochemistry/ Immunofluorescence.
target :
Lysyl Oxidase Homolog 2/LOXL2
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
5D2
conjugate :
Unconjugated
host :
Mouse
immunogen :
NFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVV
INPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSF
SEETEKKFEHFSGLLNNQLSP
LOXL2 (NP_002309, 675 a.a. ~ 773 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2b Kappa
purity :
IgG purified
species :
Human,Mouse
specificity :
LOXL2 - lysyl oxidase-like 2
gene symbol :
LOXL2
accessionNumbers :
NP_002309
applications :
ELISA,Immunohistochemistry,Western Blot,Sandwich ELISA,Immunocytochemistry/ Immunofluorescence
USD :
529 USD
alt names :
EC 1.4.3, EC 1.4.3.-, LOR2, lysyl oxidase homolog 2, lysyl oxidase related 2, lysyl oxidase-like 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, WS9-14
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.