KRAS Antibody (3B10-2F2) - Azide and BSA Free | Novus Biologicals H00003845-M01 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

KRAS Antibody (3B10-2F2) - Azide and BSA Free

catalog :

H00003845-M01

quantity :

0.1 mg

price :

519 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B10-2F2

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 18

Reference
Chapeau E, Sansregret L, Galli G, Ch xe8 ne P, Wartmann M, Mourikis T, et al. Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers. Nat Cancer. 2024;5:1102-1120 pubmed publisher
Amen A, Loughran R, Huang C, Lew R, Ravi A, Guan Y, et al. Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi. Cell Rep Methods. 2022;2:100239 pubmed publisher
Bill A, Espinola S, Guthy D, Haling J, Lanter M, Lu M, et al. EndoBind detects endogenous protein-protein interactions in real time. Commun Biol. 2021;4:1085 pubmed publisher
Lee S, Jeon Y, Kang J, Jang H, Lee H, Kim S. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer. Cancers (Basel). 2020;12: pubmed publisher
Yaqoob A, Li W, Liu V, Wang C, Mackedenski S, Tackaberry L, et al. Grifolin, neogrifolin and confluentin from the terricolous polypore Albatrellus flettii suppress KRAS expression in human colon cancer cells. PLoS ONE. 2020;15:e0231948 pubmed publisher
Sherekar M, Han S, Ghirlando R, Messing S, Drew M, Rabara D, et al. Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer. J Biol Chem. 2020;295:1105-1119 pubmed publisher
Cao S, Chung S, Kim S, Li Z, Manor D, Buck M. K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function. J Biol Chem. 2019;294:7068-7084 pubmed publisher
Ahmed T, Adamopoulos C, Karoulia Z, Wu X, Sachidanandam R, Aaronson S, et al. SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors. Cell Rep. 2019;26:65-78.e5 pubmed publisher
García Berrocoso T, Llombart V, Colàs Campàs L, Hainard A, Licker V, Penalba A, et al. Single Cell Immuno-Laser Microdissection Coupled to Label-Free Proteomics to Reveal the Proteotypes of Human Brain Cells After Ischemia. Mol Cell Proteomics. 2018;17:175-189 pubmed publisher
Kuracha M, Thomas P, Loggie B, Govindarajan V. Bilateral blockade of MEK- and PI3K-mediated pathways downstream of mutant KRAS as a treatment approach for peritoneal mucinous malignancies. PLoS ONE. 2017;12:e0179510 pubmed publisher
Forzati F, De Martino M, Esposito F, Sepe R, Pellecchia S, Malapelle U, et al. miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene. BMC Cancer. 2017;17:170 pubmed publisher
Madureira P, Bharadwaj A, Bydoun M, Garant K, O Connell P, Lee P, et al. Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10. Oncotarget. 2016;7:47720-47737 pubmed publisher
Ambrosini G, Khanin R, Carvajal R, Schwartz G. Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells. Mol Cancer Ther. 2014;13:2073-80 pubmed publisher
King S, Bray S, Galbraith S, Christie L, Fleming S. Evidence for aldosterone-dependent growth of renal cell carcinoma. Int J Exp Pathol. 2014;95:244-50 pubmed publisher
Subramani A, Alsidawi S, Jagannathan S, Sumita K, Sasaki A, Aronow B, et al. The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis. Sci Rep. 2013;3:2392 pubmed publisher
Valtorta E, Misale S, Sartore Bianchi A, Nagtegaal I, Paraf F, Lauricella C, et al. KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. Int J Cancer. 2013;133:1259-65 pubmed publisher
Hsu S, Lee W. Progesterone receptor activation of extranuclear signaling pathways in regulating p53 expression in vascular endothelial cells. Mol Endocrinol. 2011;25:421-32 pubmed publisher
Fuentes Calvo I, Blázquez Medela A, Santos E, Lopez Novoa J, Martinez Salgado C. Analysis of k-ras nuclear expression in fibroblasts and mesangial cells. PLoS ONE. 2010;5:e8703 pubmed publisher

product information

master code :

H00003845-M01

SKU :

H00003845-M01

product name :

KRAS Antibody (3B10-2F2) - Azide and BSA Free

unit size :

0.1 mg

description :

The KRAS Antibody (3B10-2F2) - Azide and BSA Free from Novus is a mouse monoclonal antibody to KRAS. This antibody reacts with human,mouse. The KRAS Antibody (3B10-2F2) - Azide and BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA.

target :

KRAS

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

3B10-2F2

conjugate :

Unconjugated

host :

Mouse

immunogen :

MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDS
YRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGF
LCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNK
CDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAF
YTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM
KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG1 Kappa

purity :

IgG purified

species :

Human,Mouse

specificity :

KRAS - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

gene symbol :

KRAS

accessionNumbers :

AAH13572

applications :

Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA

USD :

519 USD

alt names :

cellular c-Ki-ras2 proto-oncogene, c-Ki-ras, C-K-RAS, GTPase KRas, Ki-Ras, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, K-Ras 2, K-ras p21 protein, KRAS1, K-RAS2A, K-RAS2B, KRAS2NS3, K-RAS4A, K-RAS4B, NS, oncogene KRAS2, PR310 c-K-ras oncogene, RASK2c-Kirsten-ras protein, transforming protein p21, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage