product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Importin alpha 5/KPNA1/SRP1 Antibody (2A4-1B5) - Azide and BSA Free
catalog :
H00003836-M01
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2A4-1B5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 6
Reference
Kim N, Yoshimaru T, Chen Y, Matsuo T, Komatsu M, Miyoshi Y, et al. BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells. PLoS ONE. 2015;10:e0127707 pubmed publisher
Moriyama T, Sangel P, Yamaguchi H, Obuse C, Miyamoto Y, Oka M, et al. Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box. Biochem Biophys Res Commun. 2015;462:201-7 pubmed publisher
Hall M, Griffin C, Simionescu A, Corbett A, Pavlath G. Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells. Dev Biol. 2011;357:248-58 pubmed publisher
Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, Yoneda Y. Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery. FEBS J. 2011;278:1561-72 pubmed publisher
Nishimura A, Zupunski V, Troakes C, Kathe C, Fratta P, Howell M, et al. Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration. Brain. 2010;133:1763-71 pubmed publisher
Theiss A, Jenkins A, Okoro N, Klapproth J, Merlin D, Sitaraman S. Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression. Mol Biol Cell. 2009;20:4412-23 pubmed publisher
product information
master code :
H00003836-M01
SKU :
H00003836-M01
product name :
Importin alpha 5/KPNA1/SRP1 Antibody (2A4-1B5) - Azide and BSA Free
unit size :
0.1 mg
description :
The Importin alpha 5/KPNA1/SRP1 Antibody (2A4-1B5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Importin alpha 5/KPNA1/SRP1. This antibody reacts with human,mouse,rat. The Importin alpha 5/KPNA1/SRP1 Antibody (2A4-1B5) - Azide and BSA Free has been validated for the following applications: Immunoprecipitation,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin.
target :
Importin alpha 5/KPNA1/SRP1
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2A4-1B5
conjugate :
Unconjugated
host :
Mouse
immunogen :
MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQK
REEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMA
PGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPP
IDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIAS
GNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGN
IAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVW
ALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLAD
ACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKV
VSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPK
ESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQ
TAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLC
DLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPY
CALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTE
DEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL
KPNA1 (AAH02374.1, 1 a.a. ~ 538 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Mouse,Rat
specificity :
KPNA1 - karyopherin alpha 1 (importin alpha 5)
gene symbol :
KPNA1
accessionNumbers :
AAH02374
applications :
Immunoprecipitation,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
499 USD
alt names :
importin subunit alpha-1, importin-alpha-S1, IPOA5, karyopherin alpha 1 (importin alpha 5), Karyopherin subunit alpha-1, NPI-1SRP1importin alpha 5, Nucleoprotein interactor 1, RCH2RAG cohort protein 2, recombination activating gene cohort 2, SRP1-beta
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.