product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Islet-1 Antibody (2E7) - Azide and BSA Free
catalog :
H00003670-M05
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2.00E+07
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
citations: 8
Reference
Shi Q, Ni X, Lei M, Xia Q, Dong Y, Zhang Q, et al. Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer. Mol Med. 2021;27:47 pubmed publisher
Tian Y, Wang W, Lu Q, Chen P, Ma K, Jia Z, et al. Cross-talk of SFRP4, integrin ?1?1, and Notch1 inhibits cardiac differentiation of P19CL6 cells. Cell Signal. 2016;28:1806-15 pubmed publisher
Lizio M, Ishizu Y, Itoh M, Lassmann T, Hasegawa A, Kubosaki A, et al. Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line. Front Genet. 2015;6:331 pubmed publisher
Yang Z, Zhang Q, Lu Q, Jia Z, Chen P, Ma K, et al. ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex. Cell Cycle. 2015;14:3820-9 pubmed publisher
Zhang Q, Yang Z, Jia Z, Liu C, Guo C, Lu H, et al. ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Mol Cancer. 2014;13:181 pubmed publisher
Zhang Q, Yang Z, Wang W, Guo T, Jia Z, Ma K, et al. A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic ?-cells. Biochem Biophys Res Commun. 2014;449:295-300 pubmed publisher
Li B, Jia Z, Wang T, Wang W, Zhang C, Chen P, et al. Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells. J Cell Biochem. 2012;113:629-39 pubmed publisher
Guo T, Wang W, Zhang H, Liu Y, Chen P, Ma K, et al. ISL1 promotes pancreatic islet cell proliferation. PLoS ONE. 2011;6:e22387 pubmed publisher
product information
master code :
H00003670-M05
SKU :
H00003670-M05
product name :
Islet-1 Antibody (2E7) - Azide and BSA Free
unit size :
0.1 mg
description :
The Islet-1 Antibody (2E7) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Islet-1. This antibody reacts with human,mouse,rat. The Islet-1 Antibody (2E7) - Azide and BSA Free has been validated for the following applications: Chemotaxis,Immunoprecipitation,Western Blot,ELISA,Functional,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence.
target :
Islet-1
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2.00E+07
conjugate :
Unconjugated
host :
Mouse
immunogen :
YCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGA
GDPLSPLHPARPLQMAAEP
ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2a Kappa
purity :
IgG purified
species :
Human,Mouse,Rat
specificity :
ISL1 - ISL1 transcription factor, LIM/homeodomain, (islet-1)
gene symbol :
ISL1
accessionNumbers :
NP_002193
applications :
Chemotaxis,Immunoprecipitation,Western Blot,ELISA,Functional,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence
USD :
499 USD
alt names :
insulin gene enhancer protein ISL-1, ISL LIM homeobox 1, Isl-1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1), Islet-1, ISLET1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.