product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SHIP2/INPPL1 Antibody (3E6) - Azide and BSA Free
catalog :
H00003636-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3.00E+06
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
citations: 11
Reference
Ando K, K xfc xe7 xfc kali F, Doeraene E, Nagaraj S, Antonelli E, Thazin Htut M, et al. Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer's disease pathology progression. Acta Neuropathol. 2024;147:94 pubmed publisher
Antoine M, Vandenbroere I, Ghosh S, Erneux C, Pirson I. IRSp53 is a novel interactor of SHIP2: A role of the actin binding protein Mena in their cellular localization in breast cancer cells. Cell Signal. 2020;73:109692 pubmed publisher
Ramos A, Ghosh S, Suhel T, Chevalier C, Obeng E, Fafilek B, et al. Phosphoinositide 5-phosphatases SKIP and SHIP2 in ruffles, the endoplasmic reticulum and the nucleus: An update. Adv Biol Regul. 2020;75:100660 pubmed publisher
Ramos A, Ghosh S, Dedobbeleer M, Robe P, Rogister B, Erneux C. Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma. FEBS J. 2019;286:1120-1135 pubmed publisher
Ramos A, Ghosh S, Erneux C. The impact of phosphoinositide 5-phosphatases on phosphoinositides in cell function and human disease. J Lipid Res. 2019;60:276-286 pubmed publisher
Chan Wah Hak L, Khan S, Di Meglio I, Law A, Lucken Ardjomande Häsler S, Quintaneiro L, et al. FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis. Nat Cell Biol. 2018;20:1023-1031 pubmed publisher
Edimo W, Ramos A, Ghosh S, Vanderwinden J, Erneux C. The SHIP2 interactor Myo1c is required for cell migration in 1321 N1 glioblastoma cells. Biochem Biophys Res Commun. 2016;476:508-514 pubmed publisher
Elong Edimo W, Ghosh S, Derua R, Janssens V, Waelkens E, Vanderwinden J, et al. SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells. J Cell Sci. 2016;129:1101-14 pubmed publisher
Deneubourg L, Elong Edimo W, Moreau C, Vanderwinden J, Erneux C. Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines. Cell Signal. 2014;26:1193-203 pubmed publisher
Elong Edimo W, Vanderwinden J, Erneux C. SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts. Adv Biol Regul. 2013;53:28-37 pubmed publisher
McNulty S, Powell K, Erneux C, Kalman D. The host phosphoinositide 5-phosphatase SHIP2 regulates dissemination of vaccinia virus. J Virol. 2011;85:7402-10 pubmed publisher
product information
master code :
H00003636-M01
SKU :
H00003636-M01
product name :
SHIP2/INPPL1 Antibody (3E6) - Azide and BSA Free
unit size :
0.1 mg
description :
The SHIP2/INPPL1 Antibody (3E6) - Azide and BSA Free from Novus is a mouse monoclonal antibody to SHIP2/INPPL1. This antibody reacts with human,monkey. The SHIP2/INPPL1 Antibody (3E6) - Azide and BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA.
target :
SHIP2/INPPL1
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
3.00E+06
conjugate :
Unconjugated
host :
Mouse
immunogen :
PSDYGRPLSFPPPRIRESIQEDLAEEAPCLQGGRASGLG
EAGMSAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDL
EEAGVQDPAHKRLLLDTLQLSK
INPPL1 (NP_001558, 1159 a.a. ~ 1258 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Monkey
specificity :
INPPL1 - inositol polyphosphate phosphatase-like 1
gene symbol :
INPPL1
accessionNumbers :
NP_001558
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA
USD :
529 USD
alt names :
EC 3.1.3, EC 3.1.3.n1, inositol polyphosphate phosphatase-like 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, phosphatidylinositol-34,5-trisphosphate 5-phosphatase 2, Protein 51C, SH2 domain-containing inositol phosphatase 2, SH2 domain-containing inositol-5'-phosphatase 2, SHIP-2, SHIP251C protein
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.