product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
IDH2 Antibody (5F11) - Azide and BSA Free
catalog :
H00003418-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5F11
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Reference
x160 pa x10d kov xe1 J, Gotvaldov xe1 K, Dvo x159 xe1 k A, Urban x10d okov xe1 A, Posp xed x161 ilov xe1 K, V x11b tvi x10d ka D, et al. Biochemical Background in Mitochondria Affects 2HG Production by IDH2 and ADHFE1 in Breast Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
Smolkova K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubalek M, et al. SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. Sci Rep. 2020;10:8677 pubmed publisher
Ferreira J, Campos J, Qvit N, Qi X, Bozi L, Bechara L, et al. A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nat Commun. 2019;10:329 pubmed publisher
Gambichler T, Mamali K, Patsinakidis N, Moritz R, Mucke M, Skrygan M, et al. Decreased expression of ten-eleven translocation 2 protein is associated with progressive disease and death in patients with mycosis fungoides. Br J Dermatol. 2016;174:652-3 pubmed publisher
Gambichler T, Terras S, Kreuter A, Skrygan M. Altered global methylation and hydroxymethylation status in vulvar lichen sclerosus: further support for epigenetic mechanisms. Br J Dermatol. 2014;170:687-93 pubmed publisher
Rettberg J, Hamilton R, Mao Z, To J, Zhao L, Appt S, et al. The effect of dietary soy isoflavones before and after ovariectomy on hippocampal protein markers of mitochondrial bioenergetics and antioxidant activity in female monkeys. Brain Res. 2011;1379:23-33 pubmed publisher
product information
master code :
H00003418-M01
SKU :
H00003418-M01
product name :
IDH2 Antibody (5F11) - Azide and BSA Free
unit size :
0.1 mg
description :
The IDH2 Antibody (5F11) - Azide and BSA Free from Novus is a mouse monoclonal antibody to IDH2. This antibody reacts with human,rat. The IDH2 Antibody (5F11) - Azide and BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin.
target :
IDH2
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
5F11
conjugate :
Unconjugated
host :
Mouse
immunogen :
HYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLI
RFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHF
LNTTDFLDTIKSNLDRALGR
IDH2 (NP_002159, 354 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Rat
specificity :
IDH2 - isocitrate dehydrogenase 2 (NADP+), mitochondrial
gene symbol :
IDH2
accessionNumbers :
NP_002159
applications :
ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
529 USD
alt names :
D2HGA2, EC 1.1.1.42, ICD-M, IDH, IDHM, IDP, IDPM, isocitrate dehydrogenase [NADP], mitochondrial, isocitrate dehydrogenase 2 (NADP+), mitochondrial, mNADP-IDH, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.