HMGB1/HMG-1 Antibody (1D5) - Azide and BSA Free | Novus Biologicals H00003146-M02 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

HMGB1/HMG-1 Antibody (1D5) - Azide and BSA Free

catalog :

H00003146-M02

quantity :

0.1 mg

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D5

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Tonner H, Hunn S, Auler N, Schmelter C, Beutgen V, von Pein H, et al. A Monoclonal Anti-HMGB1 Antibody Attenuates Neurodegeneration in an Experimental Animal Model of Glaucoma. Int J Mol Sci. 2022;23: pubmed publisher
Hubert P, Roncarati P, Demoulin S, Pilard C, Ancion M, Reynders C, et al. Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy. J Immunother Cancer. 2021;9: pubmed publisher
Demoulin S, Herfs M, Somja J, Roncarati P, Delvenne P, Hubert P. HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells. Int J Cancer. 2015;137:345-58 pubmed publisher
Ko H, Hsu W, Hsieh C, Lien T, Lee T, Kou Y. High expression of high-mobility group box 1 in the blood and lungs is associated with the development of chronic obstructive pulmonary disease in smokers. Respirology. 2014;19:253-261 pubmed publisher
Hirano H, Yoshioka T, Yunoue S, Fujio S, Yonezawa H, Niiro T, et al. TLR4, IL-6, IL-18, MyD88 and HMGB1 are highly expressed in intracranial inflammatory lesions and the IgG4/IgG ratio correlates with TLR4 and IL-6. Neuropathology. 2012;32:628-37 pubmed publisher
Kijanka G, Hector S, Kay E, Murray F, Cummins R, Murphy D, et al. Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer. Gut. 2010;59:69-78 pubmed publisher
Krüger B, Krick S, Dhillon N, Lerner S, Ames S, Bromberg J, et al. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A. 2009;106:3390-5 pubmed publisher

product information

master code :

H00003146-M02

SKU :

H00003146-M02

product name :

HMGB1/HMG-1 Antibody (1D5) - Azide and BSA Free

unit size :

0.1 mg

description :

The HMGB1/HMG-1 Antibody (1D5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to HMGB1/HMG-1. This antibody reacts with human,rat. The HMGB1/HMG-1 Antibody (1D5) - Azide and BSA Free has been validated for the following applications: Microarray,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Sandwich ELISA,Sandwich ELISA Capture,Immunocytochemistry/ Immunofluorescence.

target :

HMGB1/HMG-1

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

1D5

conjugate :

Unconjugated

host :

Mouse

immunogen :

MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFS
EFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTY
IPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEH
PGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYE
KDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEE
DEEEEEDEEDEDEEEDDDDE
HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG2a Kappa

purity :

IgG purified

species :

Human,Rat

specificity :

HMGB1 - high-mobility group box 1

gene symbol :

HMGB1

accessionNumbers :

AAH03378

applications :

Microarray,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Sandwich ELISA,Sandwich ELISA Capture,Immunocytochemistry/ Immunofluorescence

USD :

499 USD

alt names :

Amphoterin, high mobility group box 1, High mobility group protein 1, high mobility group protein B1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydrate binding protein

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage