product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GART Antibody (4D6-1D5) - Azide and BSA Free
catalog :
H00002618-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4D6-1D5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
citations: 9
Reference
Doigneaux C, Pedley A, Mistry I, Papayova M, Benkovic S, Tavassoli A. Hypoxia drives the assembly of the multienzyme purinosome complex. J Biol Chem. 2020;295:9551-9566 pubmed publisher
Severi L, Losi L, Fonda S, Taddia L, Gozzi G, Marverti G, et al. Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer. Front Pharmacol. 2018;9:454 pubmed publisher
Pedley A, Benkovic S. Detecting Purinosome Metabolon Formation with Fluorescence Microscopy. Methods Mol Biol. 2018;1764:279-289 pubmed publisher
Baresova V, Krijt M, Skopova V, Souckova O, Kmoch S, Zikanova M. CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation. Mol Genet Metab. 2016;119:270-277 pubmed publisher
Genovese F, Gualandi A, Taddia L, Marverti G, Pirondi S, Marraccini C, et al. Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides. J Proteome Res. 2014;13:5250-61 pubmed publisher
Zhao A, Tsechansky M, Swaminathan J, Cook L, Ellington A, Marcotte E. Transiently transfected purine biosynthetic enzymes form stress bodies. PLoS ONE. 2013;8:e56203 pubmed publisher
Banerjee D, Ghosh D, Chatterjee A, Sinha S, Nandagopal K. No Evidence for Mutations that Deregulate GARS-AIRS-GART Protein Levels in Children with Down Syndrome. Indian J Clin Biochem. 2012;27:46-51 pubmed publisher
Noelker C, Schwake M, Balzer Geldsetzer M, Bacher M, Popp J, Schlegel J, et al. Differentially expressed gene profile in the 6-hydroxy-dopamine-induced cell culture model of Parkinson's disease. Neurosci Lett. 2012;507:10-5 pubmed publisher
Field M, Anguera M, Page R, Stover P. 5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887. Arch Biochem Biophys. 2009;481:145-50 pubmed publisher
product information
master code :
H00002618-M01
SKU :
H00002618-M01
product name :
GART Antibody (4D6-1D5) - Azide and BSA Free
unit size :
0.1 mg
description :
The GART Antibody (4D6-1D5) - Azide and BSA Free from Novus is a mouse monoclonal antibody to GART. This antibody reacts with human,mouse. The GART Antibody (4D6-1D5) - Azide and BSA Free has been validated for the following applications: Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin.
target :
GART
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
4D6-1D5
conjugate :
Unconjugated
host :
Mouse
immunogen :
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGT
ACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPL
AAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRH
GIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGK
GVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG
EEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMG
AYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGIL
YAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEV
IQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKG
VEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVT
AIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFL
QQPR
GART (AAH38958.1, 1 a.a. ~ 433 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Mouse
specificity :
GART - phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
gene symbol :
GART
accessionNumbers :
AAH38958
applications :
Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin
USD :
529 USD
alt names :
AIRS, EC 6.3.3.1, EC 6.3.4.13, GARS, GARTF, MGC47764, PGFTEC 2.1.2.210PAIS, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamidesynthetase, phosphoribosylaminoimidazole synthetase, trifunctional purine biosynthetic protein adenosine-3
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.