product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CTNS Antibody (5G6) - Azide and BSA Free
catalog :
H00001497-M09
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5G6
reactivity :
human, mouse, rat
application :
western blot, ELISA
more info or order :
citations: 3
Reference
Brasell E, Chu L, El Kares R, Seo J, Loesch R, Iglesias D, et al. The aminoglycoside geneticin permits translational readthrough of the CTNS W138X nonsense mutation in fibroblasts from patients with nephropathic cystinosis. Pediatr Nephrol. 2019;34:873-881 pubmed publisher
McEvoy B, Sumayao R, Slattery C, McMorrow T, Newsholme P. Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels. J Physiol. 2015;593:5167-82 pubmed publisher
Bellomo F, Corallini S, Pastore A, Palma A, Laurenzi C, Emma F, et al. Modulation of CTNS gene expression by intracellular thiols. Free Radic Biol Med. 2010;48:865-72 pubmed publisher
product information
master code :
H00001497-M09
SKU :
H00001497-M09
product name :
CTNS Antibody (5G6) - Azide and BSA Free
unit size :
0.1 mg
description :
The CTNS Antibody (5G6) - Azide and BSA Free from Novus is a mouse monoclonal antibody to CTNS. This antibody reacts with human,mouse,rat. The CTNS Antibody (5G6) - Azide and BSA Free has been validated for the following applications: ELISA,Western Blot.
target :
CTNS
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
5G6
conjugate :
Unconjugated
host :
Mouse
immunogen :
MIRNWLTIFILFPLKLVEKCESSVSLTVPPVVKLENGSS
TNVSLTLRPPLNATLVITFEITFRSKNITILELPDEVVV
PPGVTNSSFQVTSQNVGQLTVY
CTNS (NP_004928, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG2a Kappa
purity :
IgG purified
species :
Human,Mouse,Rat
specificity :
CTNS - cystinosis, nephropathic
gene symbol :
CTNS
accessionNumbers :
NP_004928
applications :
ELISA,Western Blot
USD :
499 USD
alt names :
CTNS-LSB, cystinosin, cystinosis, nephropathic, PQLC4
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.