product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Cystathionase Antibody (2E12-1C10) - Azide and BSA Free
catalog :
H00001491-M02
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2E12-1C10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 9
Reference
Gambari L, Lisignoli G, Gabusi E, Manferdini C, Paolella F, Piacentini A, et al. Distinctive expression pattern of cystathionine-?-synthase and cystathionine-?-lyase identifies mesenchymal stromal cells transition to mineralizing osteoblasts. J Cell Physiol. 2017;232:3574-3585 pubmed publisher
Grassi F, Tyagi A, Calvert J, Gambari L, Walker L, Yu M, et al. Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency. J Bone Miner Res. 2016;31:949-63 pubmed publisher
Jiang H, Hurt K, Breen K, Stabler S, Allen R, Orlicky D, et al. Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 2015;4:1154-62 pubmed publisher
Panza E, De Cicco P, Armogida C, Scognamiglio G, Gigantino V, Botti G, et al. Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression. Pigment Cell Melanoma Res. 2015;28:61-72 pubmed publisher
Qipshidze N, Metreveli N, Mishra P, Lominadze D, Tyagi S. Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis. Int J Biol Sci. 2012;8:430-41 pubmed publisher
Kundu S, Munjal C, Tyagi N, Sen U, Tyagi A, Tyagi S. Folic acid improves inner ear vascularization in hyperhomocysteinemic mice. Hear Res. 2012;284:42-51 pubmed publisher
Dickhout J, Carlisle R, Jerome D, Mohammed Ali Z, Jiang H, Yang G, et al. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012;287:7603-14 pubmed publisher
Maclean K, Sikora J, Kozich V, Jiang H, Greiner L, Kraus E, et al. A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab. 2010;101:153-62 pubmed publisher
d Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, et al. Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proc Natl Acad Sci U S A. 2009;106:4513-8 pubmed publisher
product information
master code :
H00001491-M02
SKU :
H00001491-M02
product name :
Cystathionase Antibody (2E12-1C10) - Azide and BSA Free
unit size :
0.1 mg
description :
The Cystathionase Antibody (2E12-1C10) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Cystathionase. This antibody reacts with human,mouse. The Cystathionase Antibody (2E12-1C10) - Azide and BSA Free has been validated for the following applications: Western Blot,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Sandwich ELISA,Immunocytochemistry/ Immunofluorescence.
target :
Cystathionase
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2E12-1C10
conjugate :
Unconjugated
host :
Mouse
immunogen :
MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVP
PISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAAL
DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGT
NRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWI
ETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF
QRPLALGADISMYSATKYMNGRSDVVMGLVSVNCESLHN
RLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG
MAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTG
MVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELP
AIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDL
DQALKAAHPPSGSHS
CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Mouse
specificity :
CTH - cystathionase (cystathionine gamma-lyase)
gene symbol :
CTH
accessionNumbers :
AAH15807
applications :
Western Blot,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Sandwich ELISA,Immunocytochemistry/ Immunofluorescence
USD :
529 USD
alt names :
cystathionase (cystathionine gamma-lyase), cystathionine gamma-lyase, cysteine desulfhydrase, EC 4.4.1, EC 4.4.1.1, gamma-cystathionase, homoserine deaminase, homoserine dehydratase, MGC9471
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.