product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Blk Antibody (7A12) - Azide and BSA Free
catalog :
H00000640-M02
quantity :
0.1 mg
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7A12
reactivity :
human, mouse, rat
application :
western blot, ELISA, flow cytometry
more info or order :
citations: 4
Reference
Ni J, Li X, Tu X, Zhu H, Wang S, Hou Y, et al. Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells. Int Immunopharmacol. 2023;114:109487 pubmed publisher
Bernal QuirĂ³s M, Wu Y, Alarcon Riquelme M, Castillejo Lopez C. BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling. PLoS ONE. 2013;8:e59842 pubmed publisher
Simpfendorfer K, Olsson L, Manjarrez Orduno N, Khalili H, Simeone A, Katz M, et al. The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development. Hum Mol Genet. 2012;21:3918-25 pubmed publisher
Castillejo Lopez C, Delgado Vega A, Wojcik J, Kozyrev S, Thavathiru E, Wu Y, et al. Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. Ann Rheum Dis. 2012;71:136-42 pubmed publisher
product information
master code :
H00000640-M02
SKU :
H00000640-M02
product name :
Blk Antibody (7A12) - Azide and BSA Free
unit size :
0.1 mg
description :
The Blk Antibody (7A12) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Blk. This antibody reacts with human,mouse,rat. The Blk Antibody (7A12) - Azide and BSA Free has been validated for the following applications: Flow Cytometry,Western Blot,ELISA.
target :
Blk
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
7A12
conjugate :
Unconjugated
host :
Mouse
immunogen :
MGLVSSKKPDKEKPIKEKDKGQWSPLKVSAQDKDAPPLP
PLVVFNHLTPPPPDEHLDEDKHFVVALYDYTAMNDRDLQ
MLKGEKLQVLKG
BLK (AAH07371, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Mouse,Rat
specificity :
BLK - B lymphoid tyrosine kinase
gene symbol :
BLK
accessionNumbers :
AAH07371
applications :
Flow Cytometry,Western Blot,ELISA
USD :
499 USD
alt names :
B lymphocyte kinase, B lymphoid tyrosine kinase, BLK nonreceptor tyrosine kinase, EC 2.7.10.2, MGC10442, MODY11, p55-Blk, tyrosine-protein kinase Blk
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.